Anmärkning: | Receptors, Immunologic (1989-1995) | Secretory Component (1992-1995) X |
Anmärkning: | Specialized Fc receptors (RECEPTORS, FC) for polymeric immunoglobulins, which mediate transcytosis of polymeric IMMUNOGLOBULIN A and IMMUNOGLOBULIN M into external secretions. They are found on the surfaces of epithelial cells and hepatocytes. After binding to IMMUNOGLOBULIN A, the receptor-ligand complex undergoes endocytosis, transport by vesicle, and secretion into the lumen by exocytosis. Before release, the part of the receptor (SECRETORY COMPONENT) that is bound to IMMUNOGLOBULIN A is proteolytically cleaved from its transmembrane tail. (From Rosen et al., The Dictionary of Immunology, 1989)
X |
Termer och motsvarande begrepp: | Polymeerinen immunoglobuliinireseptori (fi, ersatt) Receptors, Polymeric Immunoglobulin (en) Receptor, Polyimmunoglobulin (en, ersatt) Receptor, Polymeric Ig (en, ersatt) Polymeric Immunoglobulin Receptors (en, ersatt) Polymeric Immunoglobulin Receptor (en, ersatt) Polyimmunoglobulin Receptor (en, ersatt) Polymeric Ig Receptor (en, ersatt) Poly-Ig Receptor (en, ersatt)
X |