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C-peptid
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Anmärkning: | The middle segment of proinsulin that is between the N-terminal B-chain and the C-terminal A-chain. It is a pancreatic peptide of about 31 residues, depending on the species. Upon proteolytic cleavage of proinsulin, equimolar INSULIN and C-peptide are released. C-peptide immunoassay has been used to assess pancreatic beta cell function in diabetic patients with circulating insulin antibodies or exogenous insulin. Half-life of C-peptide is 30 min, almost 8 times that of insulin.
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Annotation: | from proinsulin only: not for peptide fragments from other proteins ( = PEPTIDE FRAGMENTS)
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historyNote*: | 84(77); was see under PEPTIDES 1977-83
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publicMeSHNote*: | 84; was see under PEPTIDES 1977-83
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activeMeSHYear*: | 2007X |
dateCreated*: | 1976-04-16X |
dateEstablished*: | 1984-01-01X |
dateRevised*: | 2006-07-05X |
recordAuthorizer*: | sjnX |
recordMaintainer*: | lktX |
recordOriginator*: | RLSX |
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Termer och motsvarande begrepp: | C-peptidi (fi) XC-Peptide (en) Proinsulin C-Peptide (en, ersatt) Connecting Peptide (en, ersatt) C-Peptide, Proinsulin (en, ersatt) |
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