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Det sätt begreppsrelationer visas:
Koleratoxin
Hierarki: | ∟ ∟ ∟ ∟ Koleratoxin 13 sidobegrepp∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ Koleratoxin 13 sidobegrepp∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ Koleratoxin 13 sidobegrepp∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ |
Bredare villkor: | |
Anmärkning: | Bacterial Proteins (1966-1977) | Bacterial Toxins (1977) | Enterotoxins (1966-1977) | Toxins (1966-1967)X |
Anmärkning: | An ENTEROTOXIN from VIBRIO CHOLERAE. It consists of two major protomers, the heavy (H) or A subunit and the B protomer which consists of 5 light (L) or B subunits. The catalytic A subunit is proteolytically cleaved into fragments A1 and A2. The A1 fragment is a MONO(ADP-RIBOSE) TRANSFERASE. The B protomer binds cholera toxin to intestinal epithelial cells, and facilitates the uptake of the A1 fragment. The A1 catalyzed transfer of ADP-RIBOSE to the alpha subunits of heterotrimeric G PROTEINS activates the production of CYCLIC AMP. Increased levels of cyclic AMP are thought to modulate release of fluid and electrolytes from intestinal crypt cells.
X |
Annotation: | /antag permitted but consider also ANTITOXINS
X |
historyNote*: | 78
X |
publicMeSHNote*: | 78
X |
activeMeSHYear*: | |
dateCreated*: | 1977-04-22X |
dateEstablished*: | 1978-01-01X |
dateRevised*: | 2005-06-30X |
recordAuthorizer*: | sjnX |
recordMaintainer*: | ssbX |
recordOriginator*: | SHX |
Typ: | |
Samordna villkor: | |
URI: | |
Termer och motsvarande begrepp: | Koleratoksiini (fi) XKoleramyrkky (fi, ersatt) Cholera Toxin (en) Choleragen (en, ersatt) Cholera Toxin Protomer B (en, ersatt) Cholera Toxin B Subunit (en, ersatt) Cholera Exotoxin (en, ersatt) Cholera Toxin A Subunit (en, ersatt) Cholera Enterotoxin CT (en, ersatt) |
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