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Histokompatibilitetsantigener klass II
Hierarki: | ∟ ∟ ∟ ∟ ∟ Histokompatibilitetsantigener klass II 3 sidobegrepp1 underordnad begrepp∟ ∟ ∟ ∟ ∟ Histokompatibilitetsantigener klass II 3 sidobegrepp1 underordnad begreppX |
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Anmärkning: | Large, transmembrane, non-covalently linked glycoproteins (alpha and beta). Both chains can be polymorphic although there is more structural variation in the beta chains. The class II antigens in humans are called HLA-D ANTIGENS and are coded by a gene on chromosome 6. In mice, two genes named IA and IE on chromosome 17 code for the H-2 antigens. The antigens are found on B-lymphocytes, macrophages, epidermal cells, and sperm and are thought to mediate the competence of and cellular cooperation in the immune response. The term IA antigens used to refer only to the proteins encoded by the IA genes in the mouse, but is now used as a generic term for any class II histocompatibility antigen.
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Annotation: | human & animal; GEN: prefer specifics; see also HLA ANTIGENS & specifics for human; X ref IA ANTIGENS refers to any class II histocompatibility antigen
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historyNote*: | 89; was ANTIGENS, IMMUNE RESPONSE 1981-88; I-A-ANTIGEN was NM 1987-93
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onlineNote*: | use HISTOCOMPATIBILITY ANTIGENS CLASS II to search ANTIGENS, IMMUNE RESPONSE 1981-88 & I-A-ANTIGEN 1987-93
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publicMeSHNote*: | 89; was ANTIGENS, IMMUNE RESPONSE 1981-88; I-A-ANTIGEN was indexed under HISTOCOMPATIBILITY ANTIGENS CLASS II 1987-93
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activeMeSHYear*: | |
dateCreated*: | 1980-05-13X |
dateEstablished*: | 1981-01-01X |
dateRevised*: | 2005-06-30X |
recordAuthorizer*: | sjnX |
recordMaintainer*: | ssbX |
recordOriginator*: | SHX |
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Termer och motsvarande begrepp: | Kudossopeutuvuusantigeenit luokka II (fi) XHistokompatibiliteettiantigeeni luokka II (fi, ersatt) Kudossopeutuvuusantigeeni luokka II (fi, ersatt) Histokompatibiliteettiantigeenit luokka II (fi, ersatt) Histocompatibility Antigens Class II (en) Immune Response Antigens (en, ersatt) Ia-Like Antigens (en, ersatt) Immune-Response-Associated Antigens (en, ersatt) Ia Antigens (en, ersatt) IA Antigen (en, ersatt) Class II Antigens (en, ersatt) Class II Antigen (en, ersatt) Class II Histocompatibility Antigens (en, ersatt) Class II Major Histocompatibility Antigens (en, ersatt) I-A-Antigen (en, ersatt) I-A Antigen (en, ersatt) Antigens, Immune Response (en, ersatt) |
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