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GABA-modulatorer
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Anmärkning: | Substances that do not act as agonists or antagonists but do affect the GAMMA-AMINOBUTYRIC ACID receptor-ionophore complex. GABA-A receptors (RECEPTORS, GABA-A) appear to have at least three allosteric sites at which modulators act: a site at which BENZODIAZEPINES act by increasing the opening frequency of GAMMA-AMINOBUTYRIC ACID-activated chloride channels; a site at which BARBITURATES act to prolong the duration of channel opening; and a site at which some steroids may act. GENERAL ANESTHETICS probably act at least partly by potentiating GABAergic responses, but they are not included here.
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Annotation: | GEN or unspecified; prefer specifics
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historyNote*: | 95
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publicMeSHNote*: | 95
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activeMeSHYear*: | |
dateCreated*: | 1994-06-03X |
dateEstablished*: | 1995-01-01X |
dateRevised*: | 2005-06-30X |
recordAuthorizer*: | sjnX |
recordMaintainer*: | ssbX |
recordOriginator*: | RAZX |
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Termer och motsvarande begrepp: | GABA-muuntajat (fi) XGamma-aminovoihappomodulaattorit (fi, ersatt) Gamma-aminovoihappomuuntaja (fi, ersatt) Gamma-aminovoihappomuuntajat (fi, ersatt) Gamma-aminovoihappomodulaattori (fi, ersatt) GABA-muuntaja (fi, ersatt) GABA-modulaattori (fi, ersatt) GABA-modulaattorit (fi, ersatt) GABA Modulators (en) gamma-Aminobutyric Acid Modulators (en, ersatt) GABAergic Modulators (en, ersatt) |
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