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Anmärkning: | Immunoglobulin Isotypes/biosynthesis (1988-1993) | Immunoglobulins, Heavy-Chain/genetics (1980-1993)X |
Anmärkning: | Gene rearrangement of the B-lymphocyte which results in a substitution in the type of heavy-chain constant region that is expressed. This allows the effector response to change while the antigen binding specificity (variable region) remains the same. The majority of class switching occurs by a DNA recombination event but it also can take place at the level of RNA processing.
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historyNote*: | 94
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publicMeSHNote*: | 94
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activeMeSHYear*: | |
dateCreated*: | 1993-06-17X |
dateEstablished*: | 1994-01-01X |
dateRevised*: | 2002-07-03X |
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Termer och motsvarande begrepp: | Immunoglobuliiniluokan vaihtuminen (fi) XImmunoglobuliiniluokan vaihtaminen (fi, ersatt) Immunoglobulin Class Switching (en) Isotype Switching (en, ersatt) Class Switching (en, ersatt) |
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