Esitystapa käsitteiden/termien suhteille:
Näytä käsitteiden/termien suhteet:
Näytä käsitteiden/termien suhteet:
Fokaalinen adheesiokinaasi 1
Laajemmat termit: | ∟ ∟ ∟ ∟ ∟ Fokaalinen adheesiokinaasi 1 ∟ ∟ ∟ ∟ Fokaalinen adheesiokinaasi 1 ∟ ∟ ∟ ∟ ∟ Fokaalinen adheesiokinaasi 1 ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ Fokaalinen adheesiokinaasi 1 |
historyNote*: | 2006(1986)
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Huomautus: | A non-receptor protein tyrosine kinase that is localized to FOCAL ADHESIONS and is a central component of integrin-mediated SIGNAL TRANSDUCTION PATHWAYS. Focal adhesion kinase 1 interacts with PAXILLIN and undergoes PHOSPHORYLATION in response to adhesion of cell surface integrins to the EXTRACELLULAR MATRIX. Phosphorylated p125FAK protein binds to a variety of SH2 DOMAIN and SH3 DOMAIN containing proteins and helps regulate CELL ADHESION and CELL MIGRATION.
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publicMeSHNote*: | 2006; ENDOGENOUS SUBSTRATE PP120, FOCAL ADHESION-ASSOCIATED, PROTEIN-TYROSINE KINASE PP125FAK, & P125FAK PROTEIN were indexed under PROTEIN-TYROSINE KINASE 2001-2005, & under CELL ADHESION MOLECULES 1990-2000, & MEMBRANE GLYCOPROTEINS 1987-1992, MEMBRANE PROTEINS 1986-1987
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activeMeSHYear*: | 2006 2006A 2007 |
dateCreated*: | 2005-06-30 |
dateEstablished*: | 2006-01-01 |
dateRevised*: | 2005-07-18 |
recordAuthorizer*: | ags |
recordMaintainer*: | ags |
recordOriginator*: | DRC |
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URI: | |
Nimikkeet ja vastaavat käsitteet: | Focal Adhesion Kinase 1 (en) p125FAK Protein (en, korvattu) Focal Adhesion-Associated Protein-Tyrosine Kinase pp125FAK (en, korvattu) Endogenous Substrate pp120 (en, korvattu) |
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