Esitystapa käsitteiden/termien suhteille:
Näytä käsitteiden/termien suhteet:
Näytä käsitteiden/termien suhteet:
Poly(A):n sitojaproteiini II
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historyNote*: | 2003; for PAB II use POLY(A)-BINDING PROTEINS (NM) 1995-2002; for PABP2 GENE PRODUCT & PABP2 PROTEIN use POLY(A)-BINDING PROTEINS (NM) 1999-2002; for PABP2 use POLY(A)-BINDING PROTEINS (NM) 2000-2002
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Huomautus: | RNA-Binding Proteins (1995-2002)X |
Huomautus: | A poly(A) binding protein that is involved in promoting the extension of the poly A tails of MRNA. The protein requires a minimum of ten ADENOSINE nucleotides in order for binding to mRNA. Once bound it works in conjunction with CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR to stimulate the rate of poly A synthesis by POLY A POLYMERASE. Once poly-A tails reach around 250 nucleotides in length poly(A) binding protein II no longer stimulates POLYADENYLATION. Mutations within a GCG repeat region in the gene for poly(A) binding protein II have been shown to cause the disease MUSCULAR DYSTROPHY, OCULOPHARYNGEAL.
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publicMeSHNote*: | 2003; PAB II was indexed under RNA-BINDING PROTEINS 1995-2002; PABP2 GENE PRODUCT & PABP2 PROTEIN were indexed under RNA-BINDING PROTEINS 1999-2002; PABP2 was indexed under RNA-BINDING PROTEINS 2000-2002
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activeMeSHYear*: | |
dateCreated*: | 2002-07-03X |
dateEstablished*: | 2003-01-01X |
recordAuthorizer*: | sjnX |
recordMaintainer*: | jmpX |
recordOriginator*: | jmpX |
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URI: | |
Nimikkeet ja vastaavat käsitteet: | Poly(A)-bindande protein II (sv) XPoly(A)-Binding Protein II (en) Poly(A) Binding Protein II (en, korvattu) Poly(A) Binding Protein, Nuclear 1 (en, korvattu) Pabp2 Protein (en, korvattu) Pabp2 Gene Product (en, korvattu) PAB2 Poly(A) Binding Protein (en, korvattu) PABP2 (en, korvattu) PAB II (en, korvattu) |
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