Esitystapa käsitteiden/termien suhteille:
Näytä käsitteiden/termien suhteet:
Näytä käsitteiden/termien suhteet:
Amyloidibeetaproteiinin esiaste
Hierarkia: | ∟ ∟ ∟ ∟ ∟ Amyloidibeetaproteiinin esiaste 9 vieruskäsitettä∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ Amyloidibeetaproteiinin esiaste 9 vieruskäsitettä∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ Amyloidibeetaproteiinin esiaste 9 vieruskäsitettä∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ |
Laajemmat termit: | |
Annotaatio: | /drug eff /ultrastruct permitted; DF: ABPP
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historyNote*: | 92; was AMYLOID BETA PROTEIN PRECURSOR (NM) 1988-91; AMYLOID A4 PROTEIN PRECURSOR was NM 1987-94
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Huomautus: | |
Huomautus: | A precursor to the AMYLOID-BETA PROTEIN (beta/A4). Alterations in the expression of the amyloid beta-protein precursor (ABPP) gene, located on chromosome 21, plays a role in the development of the neuropathology common to both ALZHEIMER DISEASE and DOWN SYNDROME. ABPP is associated with the extensive extracellular matrix secreted by neuronal cells. Upon cleavage, this precursor produces three proteins of varying amino acid lengths: 695, 751, and 770. The beta/A4 (695 amino acids) or beta-amyloid protein is the principal component of the extracellular amyloid in senile plaques found in ALZHEIMER DISEASE; DOWN SYNDROME and, to a limited extent, in normal aging.
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onlineNote*: | use AMYLOID BETA-PROTEIN PRECURSOR (NM) to search AMYLOID BETA-PROTEIN PRECURSOR 1988-91 & AMYLOID A4 PROTEIN PRECURSOR 1987-94
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publicMeSHNote*: | 92; AMYLOID BETA-PROTEIN PRECURSOR was indexed under AMYLOID BETA-PROTEIN 1990-91 and AMYLOID & PROTEIN PRECURSORS 1988-91; AMYLOID A4 PROTEIN PRECURSOR was indexed under AMYLOID BETA-PROTEIN PRECURSOR 1993-94, AMYLOID BETA-PROTEIN 1991-92, PROTEIN PRECURSORS 1987-92, & AMYLOID 1987-90
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activeMeSHYear*: | |
dateCreated*: | 1991-07-12X |
dateEstablished*: | 1992-01-01X |
dateRevised*: | 2004-07-07X |
recordAuthorizer*: | sjnX |
recordMaintainer*: | nnsX |
recordOriginator*: | MXRX |
Tyyppi: | |
Vierustermit: | |
URI: | |
Nimikkeet ja vastaavat käsitteet: | Amyloidibeetaproteiinin prekursori (fi, korvattu) XAmyloid-betaproteinprekursor (sv) Amyloid beta-Protein Precursor (en) beta-Amyloid Protein Precursor (en, korvattu) Amyloid Protein Precursor (en, korvattu) Amyloid beta Precursor Protein (en, korvattu) Amyloid A4 Protein Precursor (en, korvattu) |
Jaa: |
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