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Zalcitabin
Hierarki: | ∟ ∟ ∟ ∟ ∟ ∟ ∟ Zalcitabin 5 sidobegrepp1 underordnad begrepp∟ ∟ ∟ ∟ ∟ ∟ Zalcitabin 5 sidobegrepp1 underordnad begrepp∟ ∟ ∟ ∟ ∟ ∟ Zalcitabin 5 sidobegrepp1 underordnad begrepp∟ ∟ ∟ ∟ ∟ ∟ ∟ Zalcitabin 5 sidobegrepp1 underordnad begrepp∟ ∟ ∟ ∟ ∟ ∟ ∟ Zalcitabin 5 sidobegrepp1 underordnad begrepp∟ ∟ ∟ ∟ ∟ Zalcitabin 5 sidobegrepp1 underordnad begrepp∟ ∟ ∟ ∟ ∟ Zalcitabin 5 sidobegrepp1 underordnad begrepp∟ ∟ ∟ ∟ ∟ ∟ Zalcitabin 5 sidobegrepp1 underordnad begrepp∟ ∟ ∟ ∟ ∟ ∟ Zalcitabin 5 sidobegrepp1 underordnad begreppX |
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Anmärkning: | A dideoxynucleoside compound in which the 3'-hydroxy group on the sugar moiety has been replaced by a hydrogen. This modification prevents the formation of phosphodiester linkages which are needed for the completion of nucleic acid chains. The compound is a potent inhibitor of HIV replication at low concentrations, acting as a chain-terminator of viral DNA by binding to reverse transcriptase. Its principal toxic side effect is axonal degeneration resulting in peripheral neuropathy.
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historyNote*: | 94; was DIDEOXYCYTIDINE 1990-93
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onlineNote*: | use ZALCITABINE to search DIDEOXYCYTIDINE 1990-93
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publicMeSHNote*: | 94; was DIDEOXYCYTIDINE 1990-93
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activeMeSHYear*: | 2007X |
dateCreated*: | 1989-07-14X |
dateEstablished*: | 1990-01-01X |
dateRevised*: | 2006-07-05X |
recordAuthorizer*: | sjnX |
recordMaintainer*: | ssbX |
recordOriginator*: | AGSX |
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Termer och motsvarande begrepp: | Tsalsitabiini (fi) XDideoxicytidin (sv, ersatt) Hivid (sv, ersatt) Zalcitabine (en) Roche Brand of Zalcitabine (en, ersatt) Hoffman-La Roche Brand of Zalcitabine (en, ersatt) HIVID Roche (en, ersatt) ddC (Antiviral) (en, ersatt) Dideoxycytidine (en, ersatt) 2',3'-Dideoxycytidine (en, ersatt) |
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