ONKI3 | Medical Subject Headings

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The way property values are displayed: value/row values side by side

The way concept relations are shown: separately in hierarchy

Apolipoprotein E4

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Hierarchy:	Medical Subject Headings (MeSH) ∟ Amino Acids, Peptides, and Proteins ∟ Proteins ∟ Apoproteins ∟ Apolipoproteins ∟ Apolipoproteins E ∟ Apolipoprotein E4 2 coordinate concepts ∟ Apolipoprotein E2 \| ∟ Apolipoprotein E3 Medical Subject Headings (MeSH) ∟ Amino Acids, Peptides, and Proteins ∟ Proteins ∟ Lipoproteins ∟ Apolipoproteins ∟ Apolipoproteins E ∟ Apolipoprotein E4 2 coordinate concepts ∟ Apolipoprotein E2 \| ∟ Apolipoprotein E3 Medical Subject Headings (MeSH) ∟ Lipids ∟ Lipoproteins ∟ Apolipoproteins ∟ Apolipoproteins E ∟ Apolipoprotein E4 2 coordinate concepts ∟ Apolipoprotein E2 \| ∟ Apolipoprotein E3 X
Broader terms:	Medical Subject Headings (MeSH) ∟ Amino Acids, Peptides, and Proteins ∟ Proteins ∟ Apoproteins ∟ Apolipoproteins ∟ Apolipoproteins E ∟ Apolipoprotein E4 Medical Subject Headings (MeSH) ∟ Amino Acids, Peptides, and Proteins ∟ Proteins ∟ Lipoproteins ∟ Apolipoproteins ∟ Apolipoproteins E ∟ Apolipoprotein E4 Medical Subject Headings (MeSH) ∟ Lipids ∟ Lipoproteins ∟ Apolipoproteins ∟ Apolipoproteins E ∟ Apolipoprotein E4 Apolipoproteins E > Apolipoproteins > Apoproteins > Proteins > Amino Acids, Peptides, and Proteins > Medical Subject Headings (MeSH) Apolipoproteins E > Apolipoproteins > Lipoproteins > Proteins > Amino Acids, Peptides, and Proteins > Medical Subject Headings (MeSH) Apolipoproteins E > Apolipoproteins > Lipoproteins > Lipids > Medical Subject Headings (MeSH) X
History note:	Apolipoproteins E (1982-2006)X
historyNote*:	2007 (1982) X
publicMeSHNote*:	2007; APOLIPOPROTEIN E-4 was indexed under APOLIPOPROTEINS E 1985-2006 & under APOLIPPROTEINS 1982-1984 X
Scope note:	A major and the second most common isoform of apolipoprotein E. In humans, Apo E4 differs from APOLIPOPROTEIN E3 at only one residue 112 (cysteine is replaced by arginine), and exhibits a lower resistance to denaturation and greater propensity to form folded intermediates. Apo E4 is a risk factor for ALZHEIMER DISEASE and CARDIOVASCULAR DISEASES. X
activeMeSHYear*:	2007X
dateCreated*:	2006-07-05X
dateEstablished*:	2007-01-01X
recordAuthorizer*:	sjnX
recordMaintainer*:	lktX
recordOriginator*:	lktX
Type:	Concept X
Coordinate terms:	Apolipoprotein E2 \| Apolipoprotein E3 X
URI:	X
Labels and equivalent concepts:	Apolipoproteiini E4 (fi) Apolipoprotein E-4 (en, replaced) ApoE4 (en, replaced) Apo E4 (en, replaced) Apo E-4 (en, replaced) Apo E epsilon 4 (en, replaced) X
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