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Apolipoprotein C-III
Hierarchy: | ∟ ∟ ∟ ∟ ∟ ∟ Apolipoprotein C-III 2 coordinate concepts∟ ∟ ∟ ∟ ∟ ∟ Apolipoprotein C-III 2 coordinate concepts∟ ∟ ∟ ∟ ∟ Apolipoprotein C-III 2 coordinate conceptsX |
Broader terms: | |
History note: | Apolipoproteins C (1977-2006)X |
historyNote*: | 2007; use APOLIPOPROTEIN C-III (NM) 1979-2006
X |
publicMeSHNote*: | 2007; APOLIPOPROTEIN C-III was indexed under APOLIPOPROTEINS C 1985-2006 & under APOLIPOPROTEINS 1979-1984
X |
Scope note: | A 9-kDa protein component of VERY-LOW-DENSITY LIPOPROTEINS and CHYLOMICRON REMNANTS. Apo C-III, synthesized in the liver, is an inhibitor of LIPOPROTEIN LIPASE. Apo C-III modulates the binding of chylomicron remnants and VLDL to receptors (RECEPTORS, LDL) thus decreases the uptake of triglyceride-rich particles by the liver cells and subsequent degradation. The normal Apo C-III is glycosylated. There are several polymorphic forms with varying amounts of SIALIC ACID (Apo C-III-0, Apo C-III-1, and Apo C-III-2).
X |
activeMeSHYear*: | 2007X |
dateCreated*: | 2006-07-05X |
dateEstablished*: | 2007-01-01X |
recordAuthorizer*: | sjnX |
recordMaintainer*: | lktX |
recordOriginator*: | lktX |
Type: | |
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URI: | |
Labels and equivalent concepts: | Apolipoproteiini C-III (fi) XSialyl Apolipoprotein C-III (en, replaced) Apolipoprotein CIII (en, replaced) Apo C-III (en, replaced) |
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