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Calgranulin A
Hierarchy: | ∟ ∟ ∟ ∟ ∟ ∟ ∟ Calgranulin A 1 coordinate concept∟ ∟ ∟ ∟ ∟ ∟ Calgranulin A 1 coordinate concept∟ ∟ ∟ ∟ ∟ Calgranulin A 1 coordinate conceptX |
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History note: | |
historyNote*: | 2003; use CALGRANULIN A (NM) 1998-2002;
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publicMeSHNote*: | 2003; CALGRANULIN A was indexed under CALCIUM-BINDING BINDING PROTEINS 1989-2002; MRP-8 PROTEIN (now CALGRANULIN A) was indexed under ANTIGENS, DIFFERENTIATION & CALCIUM-BINDING PROTEINS 1989-2002
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Scope note: | A 10.8-kDa member of the S-100 family of calcium-binding proteins that can form homo- or heterocomplexes with CALGRANULIN B and a variety of other proteins. The calgranulin A/B heterodimer is known as LEUKOCYTE L1 ANTIGEN COMPLEX. Calgranulin A is found in many cell types including GRANULOCYTES; KERATINOCYTES; and myelomonocytes, and has been shown to act as a chemotactic substance for NEUTROPHILS. Because it is present in acute inflammation but absent in chronic inflammation, it is a useful biological marker for a number of pathological conditions.
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activeMeSHYear*: | |
dateCreated*: | 2002-07-02X |
dateEstablished*: | 2003-01-01X |
dateRevised*: | 2005-07-15X |
recordAuthorizer*: | agsX |
recordMaintainer*: | agsX |
recordOriginator*: | MDJX |
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Labels and equivalent concepts: | Kalgranuliini A (fi) XMRP8 Protein (en, replaced) Myeloid Calcium-Binding Protein P8 (en, replaced) S100 A8 Protein (en, replaced) S100A8 Protein (en, replaced) MRP-8 Protein (en, replaced) Macrophage-Related Protein-8 (en, replaced) CABP-P8 (en, replaced) Cystic Fibrosis Antigen (en, replaced) Leukocyte L1 Protein Light Chain (en, replaced) 60B8-B Antigen (en, replaced) |
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