ONKI3 | Medical Subject Headings

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Gangliosidoses, GM2

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Hierarchy:	Medical Subject Headings (MeSH) ∟ Congenital, Hereditary, and Neonatal Diseases and Abnormalities ∟ Genetic Diseases, Inborn ∟ Metabolism, Inborn Errors ∟ Brain Diseases, Metabolic, Inborn ∟ Lysosomal Storage Diseases, Nervous System ∟ Sphingolipidoses ∟ Gangliosidoses ∟ Gangliosidoses, GM2 2 coordinate concepts 3 subordinate concepts ∟ Sandhoff Disease \| ∟ Tay-Sachs Disease \| ∟ Tay-Sachs Disease, AB Variant ∟ Gangliosidosis, GM1 \| ∟ Sandhoff Disease Medical Subject Headings (MeSH) ∟ Congenital, Hereditary, and Neonatal Diseases and Abnormalities ∟ Genetic Diseases, Inborn ∟ Metabolism, Inborn Errors ∟ Lipid Metabolism, Inborn Errors ∟ Lipidoses ∟ Sphingolipidoses ∟ Gangliosidoses ∟ Gangliosidoses, GM2 2 coordinate concepts 3 subordinate concepts ∟ Sandhoff Disease \| ∟ Tay-Sachs Disease \| ∟ Tay-Sachs Disease, AB Variant ∟ Gangliosidosis, GM1 \| ∟ Sandhoff Disease Medical Subject Headings (MeSH) ∟ Congenital, Hereditary, and Neonatal Diseases and Abnormalities ∟ Genetic Diseases, Inborn ∟ Metabolism, Inborn Errors ∟ Lysosomal Storage Diseases ∟ Lysosomal Storage Diseases, Nervous System ∟ Sphingolipidoses ∟ Gangliosidoses ∟ Gangliosidoses, GM2 2 coordinate concepts 3 subordinate concepts ∟ Sandhoff Disease \| ∟ Tay-Sachs Disease \| ∟ Tay-Sachs Disease, AB Variant ∟ Gangliosidosis, GM1 \| ∟ Sandhoff Disease Medical Subject Headings (MeSH) ∟ Nervous System Diseases ∟ Central Nervous System Diseases ∟ Brain Diseases ∟ Brain Diseases, Metabolic ∟ Brain Diseases, Metabolic, Inborn ∟ Lysosomal Storage Diseases, Nervous System ∟ Sphingolipidoses ∟ Gangliosidoses ∟ Gangliosidoses, GM2 2 coordinate concepts 3 subordinate concepts ∟ Sandhoff Disease \| ∟ Tay-Sachs Disease \| ∟ Tay-Sachs Disease, AB Variant ∟ Gangliosidosis, GM1 \| ∟ Sandhoff Disease Medical Subject Headings (MeSH) ∟ Nutritional and Metabolic Diseases ∟ Metabolic Diseases ∟ Brain Diseases, Metabolic ∟ Brain Diseases, Metabolic, Inborn ∟ Lysosomal Storage Diseases, Nervous System ∟ Sphingolipidoses ∟ Gangliosidoses ∟ Gangliosidoses, GM2 2 coordinate concepts 3 subordinate concepts ∟ Sandhoff Disease \| ∟ Tay-Sachs Disease \| ∟ Tay-Sachs Disease, AB Variant ∟ Gangliosidosis, GM1 \| ∟ Sandhoff Disease Medical Subject Headings (MeSH) ∟ Nutritional and Metabolic Diseases ∟ Metabolic Diseases ∟ Lipid Metabolism Disorders ∟ Lipidoses ∟ Sphingolipidoses ∟ Gangliosidoses ∟ Gangliosidoses, GM2 2 coordinate concepts 3 subordinate concepts ∟ Sandhoff Disease \| ∟ Tay-Sachs Disease \| ∟ Tay-Sachs Disease, AB Variant ∟ Gangliosidosis, GM1 \| ∟ Sandhoff Disease Medical Subject Headings (MeSH) ∟ Nutritional and Metabolic Diseases ∟ Metabolic Diseases ∟ Metabolism, Inborn Errors ∟ Brain Diseases, Metabolic, Inborn ∟ Lysosomal Storage Diseases, Nervous System ∟ Sphingolipidoses ∟ Gangliosidoses ∟ Gangliosidoses, GM2 2 coordinate concepts 3 subordinate concepts ∟ Sandhoff Disease \| ∟ Tay-Sachs Disease \| ∟ Tay-Sachs Disease, AB Variant ∟ Gangliosidosis, GM1 \| ∟ Sandhoff Disease Medical Subject Headings (MeSH) ∟ Nutritional and Metabolic Diseases ∟ Metabolic Diseases ∟ Metabolism, Inborn Errors ∟ Lipid Metabolism, Inborn Errors ∟ Lipidoses ∟ Sphingolipidoses ∟ Gangliosidoses ∟ Gangliosidoses, GM2 2 coordinate concepts 3 subordinate concepts ∟ Sandhoff Disease \| ∟ Tay-Sachs Disease \| ∟ Tay-Sachs Disease, AB Variant ∟ Gangliosidosis, GM1 \| ∟ Sandhoff Disease Medical Subject Headings (MeSH) ∟ Nutritional and Metabolic Diseases ∟ Metabolic Diseases ∟ Metabolism, Inborn Errors ∟ Lysosomal Storage Diseases ∟ Lysosomal Storage Diseases, Nervous System ∟ Sphingolipidoses ∟ Gangliosidoses ∟ Gangliosidoses, GM2 2 coordinate concepts 3 subordinate concepts ∟ Sandhoff Disease \| ∟ Tay-Sachs Disease \| ∟ Tay-Sachs Disease, AB Variant ∟ Gangliosidosis, GM1 \| ∟ Sandhoff Disease X
Broader terms:	Medical Subject Headings (MeSH) ∟ Congenital, Hereditary, and Neonatal Diseases and Abnormalities ∟ Genetic Diseases, Inborn ∟ Metabolism, Inborn Errors ∟ Brain Diseases, Metabolic, Inborn ∟ Lysosomal Storage Diseases, Nervous System ∟ Sphingolipidoses ∟ Gangliosidoses ∟ Gangliosidoses, GM2 Medical Subject Headings (MeSH) ∟ Congenital, Hereditary, and Neonatal Diseases and Abnormalities ∟ Genetic Diseases, Inborn ∟ Metabolism, Inborn Errors ∟ Lipid Metabolism, Inborn Errors ∟ Lipidoses ∟ Sphingolipidoses ∟ Gangliosidoses ∟ Gangliosidoses, GM2 Medical Subject Headings (MeSH) ∟ Congenital, Hereditary, and Neonatal Diseases and Abnormalities ∟ Genetic Diseases, Inborn ∟ Metabolism, Inborn Errors ∟ Lysosomal Storage Diseases ∟ Lysosomal Storage Diseases, Nervous System ∟ Sphingolipidoses ∟ Gangliosidoses ∟ Gangliosidoses, GM2 Medical Subject Headings (MeSH) ∟ Nervous System Diseases ∟ Central Nervous System Diseases ∟ Brain Diseases ∟ Brain Diseases, Metabolic ∟ Brain Diseases, Metabolic, Inborn ∟ Lysosomal Storage Diseases, Nervous System ∟ Sphingolipidoses ∟ Gangliosidoses ∟ Gangliosidoses, GM2 Medical Subject Headings (MeSH) ∟ Nutritional and Metabolic Diseases ∟ Metabolic Diseases ∟ Brain Diseases, Metabolic ∟ Brain Diseases, Metabolic, Inborn ∟ Lysosomal Storage Diseases, Nervous System ∟ Sphingolipidoses ∟ Gangliosidoses ∟ Gangliosidoses, GM2 Medical Subject Headings (MeSH) ∟ Nutritional and Metabolic Diseases ∟ Metabolic Diseases ∟ Lipid Metabolism Disorders ∟ Lipidoses ∟ Sphingolipidoses ∟ Gangliosidoses ∟ Gangliosidoses, GM2 Medical Subject Headings (MeSH) ∟ Nutritional and Metabolic Diseases ∟ Metabolic Diseases ∟ Metabolism, Inborn Errors ∟ Brain Diseases, Metabolic, Inborn ∟ Lysosomal Storage Diseases, Nervous System ∟ Sphingolipidoses ∟ Gangliosidoses ∟ Gangliosidoses, GM2 Medical Subject Headings (MeSH) ∟ Nutritional and Metabolic Diseases ∟ Metabolic Diseases ∟ Metabolism, Inborn Errors ∟ Lipid Metabolism, Inborn Errors ∟ Lipidoses ∟ Sphingolipidoses ∟ Gangliosidoses ∟ Gangliosidoses, GM2 Medical Subject Headings (MeSH) ∟ Nutritional and Metabolic Diseases ∟ Metabolic Diseases ∟ Metabolism, Inborn Errors ∟ Lysosomal Storage Diseases ∟ Lysosomal Storage Diseases, Nervous System ∟ Sphingolipidoses ∟ Gangliosidoses ∟ Gangliosidoses, GM2 Gangliosidoses > Sphingolipidoses > Lysosomal Storage Diseases, Nervous System > Brain Diseases, Metabolic, Inborn > Metabolism, Inborn Errors > Genetic Diseases, Inborn > Congenital, Hereditary, and Neonatal Diseases and Abnormalities > Medical Subject Headings (MeSH) Gangliosidoses > Sphingolipidoses > Lipidoses > Lipid Metabolism, Inborn Errors > Metabolism, Inborn Errors > Genetic Diseases, Inborn > Congenital, Hereditary, and Neonatal Diseases and Abnormalities > Medical Subject Headings (MeSH) Gangliosidoses > Sphingolipidoses > Lysosomal Storage Diseases, Nervous System > Lysosomal Storage Diseases > Metabolism, Inborn Errors > Genetic Diseases, Inborn > Congenital, Hereditary, and Neonatal Diseases and Abnormalities > Medical Subject Headings (MeSH) Gangliosidoses > Sphingolipidoses > Lysosomal Storage Diseases, Nervous System > Brain Diseases, Metabolic, Inborn > Brain Diseases, Metabolic > Brain Diseases > Central Nervous System Diseases > Nervous System Diseases > Medical Subject Headings (MeSH) Gangliosidoses > Sphingolipidoses > Lysosomal Storage Diseases, Nervous System > Brain Diseases, Metabolic, Inborn > Brain Diseases, Metabolic > Metabolic Diseases > Nutritional and Metabolic Diseases > Medical Subject Headings (MeSH) Gangliosidoses > Sphingolipidoses > Lipidoses > Lipid Metabolism Disorders > Metabolic Diseases > Nutritional and Metabolic Diseases > Medical Subject Headings (MeSH) Gangliosidoses > Sphingolipidoses > Lysosomal Storage Diseases, Nervous System > Brain Diseases, Metabolic, Inborn > Metabolism, Inborn Errors > Metabolic Diseases > Nutritional and Metabolic Diseases > Medical Subject Headings (MeSH) Gangliosidoses > Sphingolipidoses > Lipidoses > Lipid Metabolism, Inborn Errors > Metabolism, Inborn Errors > Metabolic Diseases > Nutritional and Metabolic Diseases > Medical Subject Headings (MeSH) Gangliosidoses > Sphingolipidoses > Lysosomal Storage Diseases, Nervous System > Lysosomal Storage Diseases > Metabolism, Inborn Errors > Metabolic Diseases > Nutritional and Metabolic Diseases > Medical Subject Headings (MeSH) X
Narrower terms:	Sandhoff Disease \| Tay-Sachs Disease \| Tay-Sachs Disease, AB Variant X
History note:	Sandhoff Disease (1966-1999) \| Tay-Sachs Disease (1966-1999)X
historyNote*:	2007 (2000) X
publicMeSHNote*:	2007; see GANGLIOSIDOSES GM2 2000-2006 X
Scope note:	A group of recessively inherited diseases characterized by the intralysosomal accumulation of G(M2) GANGLIOSIDE in the neuronal cells. Subtypes include mutations of enzymes in the BETA-N-ACETYLHEXOSAMINIDASE system or G(M2) ACTIVATOR PROTEIN leading to disruption of normal degradation of GANGLIOSIDES, a subclass of ACIDIC GLYCOSPHINGOLIPIDS. X
activeMeSHYear*:	2007X
dateCreated*:	1999-11-08X
dateEstablished*:	2000-01-01X
dateRevised*:	2006-07-05X
recordAuthorizer*:	sjnX
recordMaintainer*:	lktX
recordOriginator*:	KEVX
Related term:	beta-N-Acetylhexosaminidase X
Type:	Concept X
Coordinate terms:	Gangliosidosis, GM1 \| Sandhoff Disease X
URI:	X
Labels and equivalent concepts:	GM2-gangliosidoosit (fi) GM2-gangliosidoosi (fi, replaced) GM2-proteiiniaktivaatorin puute (fi, replaced) Gangliosidoosit, GM2 (fi, replaced) Gangliosidoosi GM2 (fi, replaced) Gangliosidoses GM2 (en, replaced) GM2 Gangliosidosis (en, replaced) G(M2) Gangliosidoses (en, replaced) X
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