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The way concept relations are shown:
Oncogene Proteins v-erbA
Hierarchy: | ∟ ∟ ∟ ∟ ∟ ∟ ∟ Oncogene Proteins v-erbA 19 coordinate concepts∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ Oncogene Proteins v-erbA 19 coordinate concepts∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ Oncogene Proteins v-erbA 19 coordinate concepts∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ |
Broader terms: | |
Annotation: | IM; coord with specific virus (IM); /drug eff /ultrastruct permitted; DF: note short X ref
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History note: | |
historyNote*: | 95; was ONCOGENE PROTEIN ERBA (NM) 1987-94
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onlineNote*: | use ONCOGENE PROTEINS V-ERBA (NM) to search ONCOGENE PROTEIN ERBA 1987-94
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publicMeSHNote*: | 95; ONCOGENE PROTEIN ERBA was indexed under RETROVIRIDAE PROTEINS, ONCOGENIC 1990-94 & RETROVIRIDAE PROTEINS 1987-89
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Scope note: | Transforming proteins encoded by erbA oncogenes from the avian erythroblastosis virus. They are truncated versions of c-erbA, the thyroid hormone receptor (RECEPTORS, THYROID HORMONE) that have retained both the DNA-binding and hormone-binding domains. Mutations in the hormone-binding domains abolish the transcriptional activation function. v-erbA acts as a dominant repressor of c-erbA, inducing transformation by disinhibiting proliferation.
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activeMeSHYear*: | |
dateCreated*: | 1994-05-23X |
dateEstablished*: | 1995-01-01X |
dateRevised*: | 2005-06-30X |
recordAuthorizer*: | sjnX |
recordMaintainer*: | SYSTEMX |
recordOriginator*: | AGSX |
Type: | |
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URI: | |
Labels and equivalent concepts: | V-erbA-onkogeeniproteiinit (fi) XV-erbA-syöpägeeniproteiinit (fi, replaced) V-erbA-syöpägeeniproteiini (fi, replaced) V-erbA-onkogeeniproteiini (fi, replaced) Onkogenproteiner v-erbA (sv) Onkgenproteiner v-erbA (sv, replaced) Oncogene Products v-erbA (en, replaced) v-erbA Proteins (en, replaced) erbA Oncogene Proteins (en, replaced) |
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