ONKI3 | Medical Subject Headings

The ONKI is provided as a part of the ONKI Living Lab - an open lab for testing the latest semantic web technologies in practice, with real users like you. Currently, over 10 000 people are using ONKI each month.

We hope you like the ONKI service and enjoy using it for your purposes!

If you encounter any problems or have improvement ideas, please contact the ONKI team. We are also very much interested in your success stories in using ONKI - please share your experiences!

The ONKI Team

Jouni Tuominen, Living Lab contact person, APIs, widgets, publishing of ontologies, etc.
Eero Hyvönen, professor, head of research group

Former members: Kim Viljanen, Rami Alatalo.

Building the future of the Semantic Web and beyond.

SeCo's homepage
For the latest semantic news, follow us on Twitter and fan us on Facebook!

How can we help you?

Live presentations about ONKI: what it is? how to use it?
Support for creating and publishing ontologies.
Online technical support for using ONKI.
Co-operation in projects.
And more, please ask.


Hierarchy:	Medical Subject Headings (MeSH) ∟ Biological Factors ∟ Antigens ∟ Superantigens 19 coordinate concepts 1 subordinate concept ∟ Minor Lymphocyte Stimulatory Antigens ∟ Allergens \| ∟ Antigen-Antibody Complex \| ∟ Antigens, Archaeal \| ∟ Antigens, Bacterial \| ∟ Antigens, Dermatophagoides \| ∟ Antigens, Fungal \| ∟ Antigens, Helminth \| ∟ Antigens, Heterophile \| ∟ Antigens, Neoplasm \| ∟ Antigens, Nuclear \| ∟ Antigens, Plant \| ∟ Antigens, Protozoan \| ∟ Antigens, Surface \| ∟ Antigens, T-Independent \| ∟ Antigens, Viral \| ∟ Autoantigens \| ∟ Epitopes \| ∟ Isoantigens \| ∟ Vaccines, Synthetic X
Broader terms:	Medical Subject Headings (MeSH) ∟ Biological Factors ∟ Antigens ∟ Superantigens Antigens > Biological Factors > Medical Subject Headings (MeSH) X
Narrower terms:	Minor Lymphocyte Stimulatory Antigens X
Annotation:	microbial antigens; coord IM with specific microbe /immunol (IM) X
History note:	specific antigens (1989-1993)X
historyNote*:	94 X
publicMeSHNote*:	94 X
Scope note:	Microbial antigens that have in common an extremely potent activating effect on T-cells that bear a specific variable region. Superantigens cross-link the variable region with class II MHC proteins regardless of the peptide binding in the T-cell receptor's pocket. The result is a transient expansion and subsequent death and anergy of the T-cells with the appropriate variable regions. X
activeMeSHYear*:	2006 \| 2007X
dateCreated*:	1993-07-01X
dateEstablished*:	1994-01-01X
dateRevised*:	2005-06-30X
recordAuthorizer*:	sjnX
recordMaintainer*:	ssbX
recordOriginator*:	AGSX
Related term:	Apoptosis \| Clonal Anergy \| Receptors, Antigen, T-Cell, alpha-beta X
Type:	Concept X
Coordinate terms:	Allergens \| Antigen-Antibody Complex \| Antigens, Archaeal \| Antigens, Bacterial \| Antigens, Dermatophagoides \| Antigens, Fungal \| Antigens, Helminth \| Antigens, Heterophile \| Antigens, Neoplasm \| Antigens, Nuclear \| Antigens, Plant \| Antigens, Protozoan \| Antigens, Surface \| Antigens, T-Independent \| Antigens, Viral \| Autoantigens \| Epitopes \| Isoantigens \| Vaccines, Synthetic X
URI:	X
Labels and equivalent concepts:	Superantigeenit (fi) Superantigeeni (fi, replaced) Superantigener (sv) X
Share:	X