ONKI3 | Medical Subject Headings

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Steroid 21-Hydroxylase

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Hierarchy:	Medical Subject Headings (MeSH) ∟ Amino Acids, Peptides, and Proteins ∟ Proteins ∟ Hemeproteins ∟ Cytochromes ∟ Cytochrome P-450 Enzyme System ∟ Steroid Hydroxylases ∟ Steroid 21-Hydroxylase 10 coordinate concepts 1 subordinate concept ∟ D013255Q000172* ∟ 25-Hydroxyvitamin D3 1-alpha-Hydroxylase \| ∟ Aldosterone Synthase \| ∟ Aromatase \| ∟ Cholesterol 7-alpha-Hydroxylase \| ∟ Cholesterol Side-Chain Cleavage Enzyme \| ∟ Cytochrome P-450 CYP27A1 \| ∟ Steroid 11-beta-Hydroxylase \| ∟ Steroid 12-alpha-Hydroxylase \| ∟ Steroid 16-alpha-Hydroxylase \| ∟ Steroid 17-alpha-Hydroxylase Medical Subject Headings (MeSH) ∟ Enzymes and Coenzymes ∟ Cytochromes ∟ Cytochrome P-450 Enzyme System ∟ Steroid Hydroxylases ∟ Steroid 21-Hydroxylase 10 coordinate concepts 1 subordinate concept ∟ D013255Q000172* ∟ 25-Hydroxyvitamin D3 1-alpha-Hydroxylase \| ∟ Aldosterone Synthase \| ∟ Aromatase \| ∟ Cholesterol 7-alpha-Hydroxylase \| ∟ Cholesterol Side-Chain Cleavage Enzyme \| ∟ Cytochrome P-450 CYP27A1 \| ∟ Steroid 11-beta-Hydroxylase \| ∟ Steroid 12-alpha-Hydroxylase \| ∟ Steroid 16-alpha-Hydroxylase \| ∟ Steroid 17-alpha-Hydroxylase Medical Subject Headings (MeSH) ∟ Enzymes and Coenzymes ∟ Enzymes ∟ Oxidoreductases ∟ Oxygenases ∟ Mixed Function Oxygenases ∟ Cytochrome P-450 Enzyme System ∟ Steroid Hydroxylases ∟ Steroid 21-Hydroxylase 10 coordinate concepts 1 subordinate concept ∟ D013255Q000172* ∟ 25-Hydroxyvitamin D3 1-alpha-Hydroxylase \| ∟ Aldosterone Synthase \| ∟ Aromatase \| ∟ Cholesterol 7-alpha-Hydroxylase \| ∟ Cholesterol Side-Chain Cleavage Enzyme \| ∟ Cytochrome P-450 CYP27A1 \| ∟ Steroid 11-beta-Hydroxylase \| ∟ Steroid 12-alpha-Hydroxylase \| ∟ Steroid 16-alpha-Hydroxylase \| ∟ Steroid 17-alpha-Hydroxylase Medical Subject Headings (MeSH) ∟ Enzymes and Coenzymes ∟ Enzymes ∟ Oxidoreductases ∟ Oxygenases ∟ Mixed Function Oxygenases ∟ Steroid Hydroxylases ∟ Steroid 21-Hydroxylase 10 coordinate concepts 1 subordinate concept ∟ D013255Q000172* ∟ 25-Hydroxyvitamin D3 1-alpha-Hydroxylase \| ∟ Aldosterone Synthase \| ∟ Aromatase \| ∟ Cholesterol 7-alpha-Hydroxylase \| ∟ Cholesterol Side-Chain Cleavage Enzyme \| ∟ Cytochrome P-450 CYP27A1 \| ∟ Steroid 11-beta-Hydroxylase \| ∟ Steroid 12-alpha-Hydroxylase \| ∟ Steroid 16-alpha-Hydroxylase \| ∟ Steroid 17-alpha-Hydroxylase X
Broader terms:	Medical Subject Headings (MeSH) ∟ Amino Acids, Peptides, and Proteins ∟ Proteins ∟ Hemeproteins ∟ Cytochromes ∟ Cytochrome P-450 Enzyme System ∟ Steroid Hydroxylases ∟ Steroid 21-Hydroxylase Medical Subject Headings (MeSH) ∟ Enzymes and Coenzymes ∟ Cytochromes ∟ Cytochrome P-450 Enzyme System ∟ Steroid Hydroxylases ∟ Steroid 21-Hydroxylase Medical Subject Headings (MeSH) ∟ Enzymes and Coenzymes ∟ Enzymes ∟ Oxidoreductases ∟ Oxygenases ∟ Mixed Function Oxygenases ∟ Cytochrome P-450 Enzyme System ∟ Steroid Hydroxylases ∟ Steroid 21-Hydroxylase Medical Subject Headings (MeSH) ∟ Enzymes and Coenzymes ∟ Enzymes ∟ Oxidoreductases ∟ Oxygenases ∟ Mixed Function Oxygenases ∟ Steroid Hydroxylases ∟ Steroid 21-Hydroxylase Steroid Hydroxylases > Cytochrome P-450 Enzyme System > Cytochromes > Hemeproteins > Proteins > Amino Acids, Peptides, and Proteins > Medical Subject Headings (MeSH) Steroid Hydroxylases > Cytochrome P-450 Enzyme System > Cytochromes > Enzymes and Coenzymes > Medical Subject Headings (MeSH) Steroid Hydroxylases > Cytochrome P-450 Enzyme System > Mixed Function Oxygenases > Oxygenases > Oxidoreductases > Enzymes > Enzymes and Coenzymes > Medical Subject Headings (MeSH) Steroid Hydroxylases > Mixed Function Oxygenases > Oxygenases > Oxidoreductases > Enzymes > Enzymes and Coenzymes > Medical Subject Headings (MeSH) X
Narrower terms:	D013255Q000172* X
History note:	Steroid Hydroxylases (1973-1977)X
historyNote*:	2003 (1978) X
publicMeSHNote*:	2003; see STE see STEROID 21-MONOOXYGENASE 1997-2002, see STEROID 21-HYDROXYLASE 1991-1996, see STEROID HYDROXYLASES 1978-1990; for STEROID 21-MONOOXYGENASE see STEROID 21-HYDROXYLASE 1978-1996; CYTOCHROME P-450 C21 was indexed under STEROID 21-HYDROXYLASE 2004 & under CYTOCHROME P-450 ENZYME SYSTEM 1996-2003 X
Scope note:	An adrenal microsomal cytochrome P450 enzyme that catalyzes the 21-hydroxylation of steroids in the presence of molecular oxygen and NADPH-FERRIHEMOPROTEIN REDUCTASE. This enzyme, encoded by CYP21 gene, converts progesterones to precursors of adrenal steroid hormones (CORTICOSTERONE; HYDROCORTISONE). Defects in CYP21 cause congenital adrenal hyperplasia (ADRENAL HYPERPLASIA, CONGENITAL). X
activeMeSHYear*:	2005 \| 2006 \| 2007X
dateCreated*:	1977-04-15X
dateEstablished*:	1991-01-01X
dateRevised*:	2004-07-07X
recordAuthorizer*:	sjnX
recordMaintainer*:	jmpX
recordOriginator*:	RLSX
Type:	Concept X
Coordinate terms:	25-Hydroxyvitamin D3 1-alpha-Hydroxylase \| Aldosterone Synthase \| Aromatase \| Cholesterol 7-alpha-Hydroxylase \| Cholesterol Side-Chain Cleavage Enzyme \| Cytochrome P-450 CYP27A1 \| Steroid 11-beta-Hydroxylase \| Steroid 12-alpha-Hydroxylase \| Steroid 16-alpha-Hydroxylase \| Steroid 17-alpha-Hydroxylase X
URI:	X
Labels and equivalent concepts:	Steroidi-21-hydroksylaasi (fi) Steroid-21-monooxygenas (sv) Progesterone 21-Hydroxylase (en, replaced) Steroid 21-Monooxygenase (en, replaced) Steroid-21-Hydroxylase (en, replaced) Cytochrome P450c21 (en, replaced) Cytochrome P-450(c-21) (en, replaced) Cytochrome P-450 21-Hydroxylase (en, replaced) Cytochrome P-450 c21 (en, replaced) Cytochrome P-450 CYP21 (en, replaced) 21-Hydroxylase (en, replaced) X
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