ONKI3 | Medical Subject Headings

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Hierarchy:	Medical Subject Headings (MeSH) ∟ Heterocyclic Compounds ∟ Heterocyclic Compounds with 4 or More Rings ∟ Rifamycins ∟ Rifampin 1 coordinate concept ∟ Rifabutin Medical Subject Headings (MeSH) ∟ Heterocyclic Compounds ∟ Heterocyclic Compounds, 1-Ring ∟ Lactams ∟ Lactams, Macrocyclic ∟ Rifamycins ∟ Rifampin 1 coordinate concept ∟ Rifabutin Medical Subject Headings (MeSH) ∟ Organic Chemicals ∟ Amides ∟ Lactams ∟ Lactams, Macrocyclic ∟ Rifamycins ∟ Rifampin 1 coordinate concept ∟ Rifabutin Medical Subject Headings (MeSH) ∟ Polycyclic Compounds ∟ Macrocyclic Compounds ∟ Lactams, Macrocyclic ∟ Rifamycins ∟ Rifampin 1 coordinate concept ∟ Rifabutin X
Broader terms:	Medical Subject Headings (MeSH) ∟ Heterocyclic Compounds ∟ Heterocyclic Compounds with 4 or More Rings ∟ Rifamycins ∟ Rifampin Medical Subject Headings (MeSH) ∟ Heterocyclic Compounds ∟ Heterocyclic Compounds, 1-Ring ∟ Lactams ∟ Lactams, Macrocyclic ∟ Rifamycins ∟ Rifampin Medical Subject Headings (MeSH) ∟ Organic Chemicals ∟ Amides ∟ Lactams ∟ Lactams, Macrocyclic ∟ Rifamycins ∟ Rifampin Medical Subject Headings (MeSH) ∟ Polycyclic Compounds ∟ Macrocyclic Compounds ∟ Lactams, Macrocyclic ∟ Rifamycins ∟ Rifampin Rifamycins > Heterocyclic Compounds with 4 or More Rings > Heterocyclic Compounds > Medical Subject Headings (MeSH) Rifamycins > Lactams, Macrocyclic > Lactams > Heterocyclic Compounds, 1-Ring > Heterocyclic Compounds > Medical Subject Headings (MeSH) Rifamycins > Lactams, Macrocyclic > Lactams > Amides > Organic Chemicals > Medical Subject Headings (MeSH) Rifamycins > Lactams, Macrocyclic > Macrocyclic Compounds > Polycyclic Compounds > Medical Subject Headings (MeSH) X
History note:	Rifamycins (1966-1972)X
historyNote*:	73 X
publicMeSHNote*:	73 X
Scope note:	A semisynthetic antibiotic produced from Streptomyces mediterranei. It has a broad antibacterial spectrum, including activity against several forms of Mycobacterium. In susceptible organisms it inhibits DNA-dependent RNA polymerase activity by forming a stable complex with the enzyme. It thus suppresses the initiation of RNA synthesis. Rifampin is bactericidal, and acts on both intracellular and extracellular organisms. (From Gilman et al., Goodman and Gilman's The Pharmacological Basis of Therapeutics, 9th ed, p1160) X
activeMeSHYear*:	2005 \| 2006 \| 2007X
dateCreated*:	1999-01-01X
dateEstablished*:	1973-01-01X
dateRevised*:	2004-07-07X
recordAuthorizer*:	sjnX
recordMaintainer*:	ssbX
recordOriginator*:	NLMX
Type:	Concept X
Coordinate terms:	Rifabutin X
URI:	X
Labels and equivalent concepts:	Rifampisiini (fi) RMP (fi, replaced) Rifampiini (fi, replaced) RIfadin (sv, replaced) Rifampicin (sv, replaced) Rimactan (sv, replaced) Rifampicin (en, replaced) Benemycin (en, replaced) Rifampicinum (la-FI, replaced) X
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