ONKI3 | Medical Subject Headings

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The way property values are displayed: value/row values side by side

The way concept relations are shown: separately in hierarchy

Apolipoprotein E2

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Hierarchy:	Medical Subject Headings (MeSH) ∟ Amino Acids, Peptides, and Proteins ∟ Proteins ∟ Apoproteins ∟ Apolipoproteins ∟ Apolipoproteins E ∟ Apolipoprotein E2 2 coordinate concepts ∟ Apolipoprotein E3 \| ∟ Apolipoprotein E4 Medical Subject Headings (MeSH) ∟ Amino Acids, Peptides, and Proteins ∟ Proteins ∟ Lipoproteins ∟ Apolipoproteins ∟ Apolipoproteins E ∟ Apolipoprotein E2 2 coordinate concepts ∟ Apolipoprotein E3 \| ∟ Apolipoprotein E4 Medical Subject Headings (MeSH) ∟ Lipids ∟ Lipoproteins ∟ Apolipoproteins ∟ Apolipoproteins E ∟ Apolipoprotein E2 2 coordinate concepts ∟ Apolipoprotein E3 \| ∟ Apolipoprotein E4 X
Broader terms:	Medical Subject Headings (MeSH) ∟ Amino Acids, Peptides, and Proteins ∟ Proteins ∟ Apoproteins ∟ Apolipoproteins ∟ Apolipoproteins E ∟ Apolipoprotein E2 Medical Subject Headings (MeSH) ∟ Amino Acids, Peptides, and Proteins ∟ Proteins ∟ Lipoproteins ∟ Apolipoproteins ∟ Apolipoproteins E ∟ Apolipoprotein E2 Medical Subject Headings (MeSH) ∟ Lipids ∟ Lipoproteins ∟ Apolipoproteins ∟ Apolipoproteins E ∟ Apolipoprotein E2 Apolipoproteins E > Apolipoproteins > Apoproteins > Proteins > Amino Acids, Peptides, and Proteins > Medical Subject Headings (MeSH) Apolipoproteins E > Apolipoproteins > Lipoproteins > Proteins > Amino Acids, Peptides, and Proteins > Medical Subject Headings (MeSH) Apolipoproteins E > Apolipoproteins > Lipoproteins > Lipids > Medical Subject Headings (MeSH) X
History note:	Apolipoproteins E (1984-2006)X
historyNote*:	2007 (1984) X
publicMeSHNote*:	2007; APOLIPOPROTEIN E-2 was indexed under APOLIPOPROTEINS E 1985-2006 & under APOLIPOPROTEINS 1984 X
Scope note:	One of three major isoforms of apolipoprotein E. In humans, Apo E2 differs from APOLIPOPROTEIN E3 at one residue 158 where arginine is replaced by cysteine (R158--C). In contrast to Apo E3, Apo E2 displays extremely low binding affinity for LDL receptors (RECEPTORS, LDL) which mediate the internalization and catabolism of lipoprotein particles in liver cells. ApoE2 allelic homozygosity is associated with HYPERLIPOPROTEINEMIA TYPE III. X
activeMeSHYear*:	2007X
dateCreated*:	2006-07-05X
dateEstablished*:	2007-01-01X
recordAuthorizer*:	sjnX
recordMaintainer*:	lktX
recordOriginator*:	lktX
Type:	Concept X
Coordinate terms:	Apolipoprotein E3 \| Apolipoprotein E4 X
URI:	X
Labels and equivalent concepts:	Apolipoproteiini E2 (fi) Apolipoprotein E-2 (en, replaced) Apolipoprotein E-epsilon2 (en, replaced) ApoE2 (en, replaced) APOE-epsilon2 (en, replaced) Apo E2 (en, replaced) APOE-epsilon 2 (en, replaced) Apo E-2 (en, replaced) X
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