ONKI3 | Medical Subject Headings

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Hierarchy:	Medical Subject Headings (MeSH) ∟ Amino Acids, Peptides, and Proteins ∟ Proteins ∟ Membrane Proteins ∟ Receptors, Cell Surface ∟ Receptors, Immunologic ∟ Receptors, Cytokine ∟ Receptors, Tumor Necrosis Factor ∟ Tumor Necrosis Factor Decoy Receptors ∟ Osteoprotegerin 2 coordinate concepts ∟ Receptors, Tumor Necrosis Factor, Member 10c \| ∟ Receptors, Tumor Necrosis Factor, Member 6b X
Broader terms:	Medical Subject Headings (MeSH) ∟ Amino Acids, Peptides, and Proteins ∟ Proteins ∟ Membrane Proteins ∟ Receptors, Cell Surface ∟ Receptors, Immunologic ∟ Receptors, Cytokine ∟ Receptors, Tumor Necrosis Factor ∟ Tumor Necrosis Factor Decoy Receptors ∟ Osteoprotegerin Tumor Necrosis Factor Decoy Receptors > Receptors, Tumor Necrosis Factor > Receptors, Cytokine > Receptors, Immunologic > Receptors, Cell Surface > Membrane Proteins > Proteins > Amino Acids, Peptides, and Proteins > Medical Subject Headings (MeSH) X
historyNote*:	2007(1997) X
publicMeSHNote*:	2007; OSTEOPROTEGERIN was indexed under RECEPTORS, TUMOR NECROSIS FACTOR, RECEPTORS, CYTOPLASMIC AND NUCLEAR & GLYCOPROTEINS 1997-2006 X
Scope note:	A secreted member of the TNF receptor superfamily that negatively regulates osteoclastogenesis. It is a soluble decoy receptor of RANK LIGAND that inhibits both CELL DIFFERENTIATION and function of OSTEOCLASTS by inhibiting the interaction between RANK LIGAND and RECEPTOR ACTIVATOR OF NUCLEAR FACTOR-KAPPA B. X
activeMeSHYear*:	2007X
dateCreated*:	2006-07-05X
dateEstablished*:	2007-01-01X
recordAuthorizer*:	sjnX
recordMaintainer*:	jmpX
recordOriginator*:	jmpX
Type:	Concept X
Coordinate terms:	Receptors, Tumor Necrosis Factor, Member 10c \| Receptors, Tumor Necrosis Factor, Member 6b X
URI:	X
Labels and equivalent concepts:	Osteoprotegeriini (fi) Tumor Necrosis Factor Receptor 11b (en, replaced) Tumor Necrosis Factor Receptor Superfamily, Member 11b (en, replaced) Receptors, Tumor Necrosis Factor, Member 11b (en, replaced) Osteoclastogenesis Inhibitory Factor (en, replaced) Follicular Dendritic Cell-Derived Receptor-1 (en, replaced) OCIF Protein (en, replaced) FDCR-1 Protein (en, replaced) X
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