ONKI3 | Medical Subject Headings

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Histamine H1 Antagonists, Non-Sedating

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Hierarchy:	Medical Subject Headings (MeSH) ∟ Chemical Actions and Uses ∟ Pharmacologic Actions ∟ Molecular Mechanisms of Action ∟ Neurotransmitter Agents ∟ Histamine Agents ∟ Histamine Antagonists ∟ Histamine H1 Antagonists ∟ Histamine H1 Antagonists, Non-Sedating Medical Subject Headings (MeSH) ∟ Chemical Actions and Uses ∟ Pharmacologic Actions ∟ Physiological Effects of Drugs ∟ Neurotransmitter Agents ∟ Histamine Agents ∟ Histamine Antagonists ∟ Histamine H1 Antagonists ∟ Histamine H1 Antagonists, Non-Sedating X
Broader terms:	Medical Subject Headings (MeSH) ∟ Chemical Actions and Uses ∟ Pharmacologic Actions ∟ Molecular Mechanisms of Action ∟ Neurotransmitter Agents ∟ Histamine Agents ∟ Histamine Antagonists ∟ Histamine H1 Antagonists ∟ Histamine H1 Antagonists, Non-Sedating Medical Subject Headings (MeSH) ∟ Chemical Actions and Uses ∟ Pharmacologic Actions ∟ Physiological Effects of Drugs ∟ Neurotransmitter Agents ∟ Histamine Agents ∟ Histamine Antagonists ∟ Histamine H1 Antagonists ∟ Histamine H1 Antagonists, Non-Sedating Histamine H1 Antagonists > Histamine Antagonists > Histamine Agents > Neurotransmitter Agents > Molecular Mechanisms of Action > Pharmacologic Actions > Chemical Actions and Uses > Medical Subject Headings (MeSH) Histamine H1 Antagonists > Histamine Antagonists > Histamine Agents > Neurotransmitter Agents > Physiological Effects of Drugs > Pharmacologic Actions > Chemical Actions and Uses > Medical Subject Headings (MeSH) X
History note:	Benzhydryl Compounds (1982-2002) \| Histamine H1 Antagonists (1982-2002)X
historyNote*:	2003 X
publicMeSHNote*:	2003 X
Scope note:	A class of non-sedating drugs that bind to but do not activate histamine receptors, thereby blocking the actions of histamine or histamine agonists. These antihistamines represent a heterogenous group of compounds with differing chemical structures, adverse effects, distribution, and metabolism. Compared to the early (first generation) antihistamines, these non-sedating antihistamines have greater receptor specificity, lower penetration of BLOOD-BRAIN BARRIER, and are less likely to cause drowsiness or psychomotor impairment. X
activeMeSHYear*:	2004 \| 2005 \| 2006 \| 2007X
dateCreated*:	2002-07-02X
dateEstablished*:	2003-01-01X
dateRevised*:	2003-07-09X
Type:	Concept X
URI:	X
Labels and equivalent concepts:	Väsyttämättömät antihistamiinit (fi) Väsyttämättömät H1-antagonistit (fi, replaced) Väsyttämättön H1-antagonisti (fi, replaced) Väsyttämätön antihistamiini (fi, replaced) Histamin H1-blockerare, icke-sederande (sv) Second Generation H1 Antagonists (en, replaced) Second Generation Antihistamines (en, replaced) H1 Antihistamines, Non-Sedating (en, replaced) X
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