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DNA Gyrase
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History note: | DNA Topoisomerases (1977-1978) | DNA Topoisomerases, Type II (1979-2001) | DNA, Circular (1976-1977)X |
historyNote*: | 2002; use DNA TOPOISOMERASE (ATP-HYDROLYZING) 1994-2001, use DNA GYRASE 1980-1993; for GYRA PROTEIN use DNA TOPOISOMERASE (ATP-HYDROLYZING) (NM) 1992-2001; GYRB PROTEIN use DNA TOPOISOMERASE (ATP-HYDROLYZING) (NM) 1991-2001
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publicMeSHNote*: | 2002; see DNA TOPOISOMERASE (ATP-HYDROLYZING) 1994-2001, see DNA GYRASE 1980-1993; GYRA PROTEIN was indexed under DNA TOPOISOMERASE (ATP-HYDROLYZING) (NM) 1992-2001; GYRB PROTEIN was indexed under DNA TOPOISOMERASE (ATP-HYDROLYZING) (NM) 1991-2001
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Scope note: | A bacterial DNA topoisomerase II that catalyzes ATP-dependent breakage of both strands of DNA, passage of the unbroken strands through the breaks, and rejoining of the broken strands. Gyrase binds to DNA as a heterotetramer consisting two A and two B subunits. In the presence of ATP, gyrase is able to convert relaxed circular DNA duplex into a superhelix. In the absence of ATP, supercoiled DNA is relaxed by DNA gyrase.
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activeMeSHYear*: | |
dateCreated*: | 2001-07-25X |
dateEstablished*: | 2002-01-01X |
dateRevised*: | 2003-07-09X |
recordAuthorizer*: | sjnX |
recordMaintainer*: | ssbX |
recordOriginator*: | lktX |
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Labels and equivalent concepts: | Gyraasi (fi) XDNA-gyraasi (fi, replaced) DNA-gyras (sv) gyrB Protein (en, replaced) gyrB Gene Product (en, replaced) gyrA Protein (en, replaced) gyrA Gene product (en, replaced) DNA-Gyrase (en, replaced) |
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