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Conotoxins
Hierarchy: | ∟ ∟ ∟ ∟ ∟ Conotoxins 1 coordinate concept1 subordinate concept∟ ∟ ∟ ∟ ∟ Conotoxins 1 coordinate concept1 subordinate concept∟ ∟ ∟ ∟ Conotoxins 1 coordinate concept1 subordinate concept∟ ∟ ∟ ∟ ∟ Conotoxins 1 coordinate concept1 subordinate conceptX |
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Annotation: | OMEGA-CONOTOXINS and OMEGA-CONOTOXIN GVIA are available
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History note: | Mollusk Venoms (1986-1999)X |
historyNote*: | 2000
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publicMeSHNote*: | 2000
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Scope note: | Peptide neurotoxins from the marine fish-hunting snails of the genus CONUS. They contain 13 to 29 amino acids which are strongly basic and are highly cross-linked by disulfide bonds. There are three types of conotoxins, omega-, alpha-, and mu-. OMEGA-CONOTOXINS inhibit voltage-activated entry of calcium into the presynaptic membrane and therefore the release of ACETYLCHOLINE. Alpha-conotoxins inhibit the postsynaptic acetylcholine receptor. Mu-conotoxins prevent the generation of muscle action potentials. (From Concise Encyclopedia Biochemistry and Molecular Biology, 3rd ed)
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activeMeSHYear*: | |
dateCreated*: | 1999-11-03X |
dateEstablished*: | 2000-01-01X |
dateRevised*: | 2005-06-30X |
recordAuthorizer*: | sjnX |
recordMaintainer*: | ssbX |
recordOriginator*: | adpX |
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Labels and equivalent concepts: | Konotoksiinit (fi) XKonotoksiini (fi, replaced) Mu-konotoksiini (fi, replaced) Mu-konotoksiinit (fi, replaced) Alfa-konotoksiinit (fi, replaced) Alfa-konotoksiini (fi, replaced) Konotoxiner (sv) Conotoxin (en, replaced) mu-Conotoxin (en, replaced) alpha-Conotoxin (en, replaced) |
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