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In Situ Nick-End Labeling
Hierarchy: | ∟ ∟ ∟ In Situ Nick-End Labeling 27 coordinate conceptsX |
Broader terms: | |
History note: | Apoptosis (1994-1998)X |
historyNote*: | 99
X |
publicMeSHNote*: | 99
X |
Scope note: | An in situ method for detecting areas of DNA which are nicked during APOPTOSIS. Terminal deoxynucleotidyl transferase is used to add labeled dUTP, in a template-independent manner, to the 3 prime OH ends of either single- or double-stranded DNA. The terminal deoxynucleotidyl transferase nick end labeling, or TUNEL, assay labels apoptosis on a single-cell level, making it more sensitive than agarose gel electrophoresis for analysis of DNA FRAGMENTATION.
X |
activeMeSHYear*: | 2007X |
dateCreated*: | 1998-06-10X |
dateEstablished*: | 1999-01-01X |
dateRevised*: | 2006-07-05X |
recordAuthorizer*: | sjnX |
recordMaintainer*: | nnsX |
recordOriginator*: | NDWX |
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Labels and equivalent concepts: | Nick End-Labelling, In Situ (en, replaced) XNick-End Labeling, In Situ (en, replaced) Nick-End Labelling, In Situ (en, replaced) TUNEL (en, replaced) Nick End-Labeling, In Situ (en, replaced) In Situ Nick-End Labelling (en, replaced) In Situ Nick End Labelling (en, replaced) In Situ Nick End-Labeling (en, replaced) In Situ Nick End-Labelling (en, replaced) In Situ Nick End Labeling (en, replaced) |
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