ONKI3 | Medical Subject Headings

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Hierarchy:	Medical Subject Headings (MeSH) ∟ Genetic Structures ∟ Genome ∟ Genome Components ∟ Genes ∟ Genes, Neoplasm ∟ Oncogenes ∟ Proto-Oncogenes ∟ Genes, erbA 14 coordinate concepts ∟ Genes, abl \| ∟ Genes, bcl-1 \| ∟ Genes, bcl-2 \| ∟ Genes, erbB \| ∟ Genes, fms \| ∟ Genes, fos \| ∟ Genes, jun \| ∟ Genes, mos \| ∟ Genes, myb \| ∟ Genes, myc \| ∟ Genes, ras \| ∟ Genes, rel \| ∟ Genes, sis \| ∟ Genes, src X
Broader terms:	Medical Subject Headings (MeSH) ∟ Genetic Structures ∟ Genome ∟ Genome Components ∟ Genes ∟ Genes, Neoplasm ∟ Oncogenes ∟ Proto-Oncogenes ∟ Genes, erbA Proto-Oncogenes > Oncogenes > Genes, Neoplasm > Genes > Genome Components > Genome > Genetic Structures > Medical Subject Headings (MeSH) X
Annotation:	erbA stands for "ERythroBlastosis virus, Avian"; GENES, ERBB & its specifics are also available; in titles & translations spell as erbA X
History note:	Oncogenes (1984-1994) \| Proto-Oncogenes (1987-1994)X
historyNote*:	95 X
publicMeSHNote*:	95 X
Scope note:	Genes related to the erbA DNA sequence that was first isolated from the avian erythroblastosis virus (ERYTHROBLASTOSIS VIRUS, AVIAN), v-erbA. In cells, erbA genes encode thyroid hormone receptors (RECEPTORS, THYROID HORMONE). Two distinct c-erbA genes have been identified: erbA-alpha located at 17q21; and erbA-beta located at 3p24. Truncations at the N- and C-terminals of erbA result in products resembling v-erbA. Truncations affect hormone responsiveness but not DNA binding capacity. X
activeMeSHYear*:	2006 \| 2007X
dateCreated*:	1994-05-23X
dateEstablished*:	1995-01-01X
dateRevised*:	2005-06-30X
recordAuthorizer*:	sjnX
recordMaintainer*:	nnsX
recordOriginator*:	AGSX
Related term:	Oncogene Proteins v-erbA \| Receptors, Thyroid Hormone X
Type:	Concept X
Coordinate terms:	Genes, abl \| Genes, bcl-1 \| Genes, bcl-2 \| Genes, erbB \| Genes, fms \| Genes, fos \| Genes, jun \| Genes, mos \| Genes, myb \| Genes, myc \| Genes, ras \| Genes, rel \| Genes, sis \| Genes, src X
URI:	X
Labels and equivalent concepts:	ErbA-geenit (fi) ErbA-geeni (fi, replaced) erbA-gener (sv) Gener, erbA (sv, replaced) Genes, TR-beta (en, replaced) Genes, TR-alpha (en, replaced) v-erbA Oncogenes (en, replaced) Genes, TR beta (en, replaced) Genes, TR alpha (en, replaced) Genes, erbA alpha (en, replaced) erbA Genes (en, replaced) Genes, erbA beta (en, replaced) Genes, THRA (en, replaced) Genes, THRB (en, replaced) c-erbA Proto-Oncogenes (en, replaced) X
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