ONKI3 | Medical Subject Headings

The ONKI is provided as a part of the ONKI Living Lab - an open lab for testing the latest semantic web technologies in practice, with real users like you. Currently, over 10 000 people are using ONKI each month.

We hope you like the ONKI service and enjoy using it for your purposes!

If you encounter any problems or have improvement ideas, please contact the ONKI team. We are also very much interested in your success stories in using ONKI - please share your experiences!

The ONKI Team

Jouni Tuominen, Living Lab contact person, APIs, widgets, publishing of ontologies, etc.
Eero Hyvönen, professor, head of research group

Former members: Kim Viljanen, Rami Alatalo.

Building the future of the Semantic Web and beyond.

SeCo's homepage
For the latest semantic news, follow us on Twitter and fan us on Facebook!

How can we help you?

Live presentations about ONKI: what it is? how to use it?
Support for creating and publishing ontologies.
Online technical support for using ONKI.
Co-operation in projects.
And more, please ask.


Hierarchy:	Medical Subject Headings (MeSH) ∟ Amino Acids, Peptides, and Proteins ∟ Proteins ∟ Blood Proteins ∟ Immunoproteins ∟ Complement System Proteins ∟ Anaphylatoxins ∟ Complement C5a 3 coordinate concepts 1 subordinate concept ∟ Complement C5a, des-Arginine ∟ Complement C3a \| ∟ Complement C4a \| ∟ Complement C5b Medical Subject Headings (MeSH) ∟ Amino Acids, Peptides, and Proteins ∟ Proteins ∟ Blood Proteins ∟ Immunoproteins ∟ Complement System Proteins ∟ Complement C5 ∟ Complement C5a 3 coordinate concepts 1 subordinate concept ∟ Complement C5a, des-Arginine ∟ Complement C3a \| ∟ Complement C4a \| ∟ Complement C5b X
Broader terms:	Medical Subject Headings (MeSH) ∟ Amino Acids, Peptides, and Proteins ∟ Proteins ∟ Blood Proteins ∟ Immunoproteins ∟ Complement System Proteins ∟ Anaphylatoxins ∟ Complement C5a Medical Subject Headings (MeSH) ∟ Amino Acids, Peptides, and Proteins ∟ Proteins ∟ Blood Proteins ∟ Immunoproteins ∟ Complement System Proteins ∟ Complement C5 ∟ Complement C5a Anaphylatoxins > Complement System Proteins > Immunoproteins > Blood Proteins > Proteins > Amino Acids, Peptides, and Proteins > Medical Subject Headings (MeSH) Complement C5 > Complement System Proteins > Immunoproteins > Blood Proteins > Proteins > Amino Acids, Peptides, and Proteins > Medical Subject Headings (MeSH) X
Narrower terms:	Complement C5a, des-Arginine X
History note:	Anaphylatoxins (1977-1989) \| Complement (1972-1975) \| Complement 5 (1975-1989)X
historyNote*:	2006 (1990) X
publicMeSHNote*:	2006; see COMPLEMENT 5A 1990-2005 X
Scope note:	The minor fragment formed when C5 convertase cleaves C5 into C5a and COMPLEMENT C5B. C5a is a 74-amino-acid glycopeptide with a carboxy-terminal ARGININE that is crucial for its spasmogenic activity. Of all the complement-derived anaphylatoxins, C5a is the most potent in mediating immediate hypersensitivity (HYPERSENSITIVITY, IMMEDIATE), smooth MUSCLE CONTRACTION; HISTAMINE RELEASE; and migration of LEUKOCYTES to site of INFLAMMATION. X
activeMeSHYear*:	2006 \| 2007X
dateCreated*:	1989-07-14X
dateEstablished*:	1990-01-01X
dateRevised*:	2005-06-30X
recordAuthorizer*:	sjnX
recordMaintainer*:	ssbX
recordOriginator*:	AGSX
Type:	Concept X
Coordinate terms:	Complement C3a \| Complement C4a \| Complement C5b X
URI:	X
Labels and equivalent concepts:	Komplementti C5a (fi) C5a (fi, replaced) Komplement 5a (sv) Complement Component 5a (en, replaced) Complement 5a (en, replaced) C5a Complement (en, replaced) X
Share:	X