ONKI3 | Medical Subject Headings

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The way property values are displayed: value/row values side by side

The way concept relations are shown: separately in hierarchy

Histocompatibility Antigens Class I

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Hierarchy:	Medical Subject Headings (MeSH) ∟ Biological Factors ∟ Antigens ∟ Antigens, Surface ∟ Histocompatibility Antigens ∟ Histocompatibility Antigens Class I 3 coordinate concepts 4 subordinate concepts ∟ H-2 Antigens \| ∟ HLA-A Antigens \| ∟ HLA-B Antigens \| ∟ HLA-C Antigens ∟ Histocompatibility Antigens Class II \| ∟ HLA Antigens \| ∟ Minor Histocompatibility Antigens Medical Subject Headings (MeSH) ∟ Biological Factors ∟ Antigens ∟ Isoantigens ∟ Histocompatibility Antigens ∟ Histocompatibility Antigens Class I 3 coordinate concepts 4 subordinate concepts ∟ H-2 Antigens \| ∟ HLA-A Antigens \| ∟ HLA-B Antigens \| ∟ HLA-C Antigens ∟ Histocompatibility Antigens Class II \| ∟ HLA Antigens \| ∟ Minor Histocompatibility Antigens X
Broader terms:	Medical Subject Headings (MeSH) ∟ Biological Factors ∟ Antigens ∟ Antigens, Surface ∟ Histocompatibility Antigens ∟ Histocompatibility Antigens Class I Medical Subject Headings (MeSH) ∟ Biological Factors ∟ Antigens ∟ Isoantigens ∟ Histocompatibility Antigens ∟ Histocompatibility Antigens Class I Histocompatibility Antigens > Antigens, Surface > Antigens > Biological Factors > Medical Subject Headings (MeSH) Histocompatibility Antigens > Isoantigens > Antigens > Biological Factors > Medical Subject Headings (MeSH) X
Narrower terms:	H-2 Antigens \| HLA-A Antigens \| HLA-B Antigens \| HLA-C Antigens X
Annotation:	human & animal X
History note:	Histocompatibility Antigens (1973-1988) \| HLA Antigens (1978-1988)X
historyNote*:	89 X
publicMeSHNote*:	89 X
Scope note:	Large transmembrane, polymorphic glycoproteins noncovalently associated with nonpolymorphic beta 2-microglobulin. In humans, three structural genes on chromosome 6 code for the HLA-A; HLA-B and HLA-C antigens. In mice, three genes named K, D, and L on chromosome 17 code for the H-2 antigens. Class I antigens are found on most nucleated cells and are generally detected by their reactivity with alloantisera. These antigens are recognized during graft rejection and restrict cell-mediated lysis of virus-infected cells. They are primarily associated with rheumatologic diseases and certain malignant disorders. X
activeMeSHYear*:	2006 \| 2007X
dateCreated*:	1988-06-06X
dateEstablished*:	1988-01-01X
dateRevised*:	2005-06-30X
recordAuthorizer*:	sjnX
recordMaintainer*:	ssbX
recordOriginator*:	RLSX
Type:	Concept X
Coordinate terms:	Histocompatibility Antigens Class II \| HLA Antigens \| Minor Histocompatibility Antigens X
URI:	X
Labels and equivalent concepts:	Kudossopeutuvuusantigeenit luokka I (fi) Histokompatibiliteettiantigeenit luokka I (fi, replaced) Kudossopeutuvuusantigeeni luokka I (fi, replaced) Histokompatibiliteettiantigeeni luokka I (fi, replaced) Histokompatibilitetsantigener klass I (sv) Class I Major Histocompatibility Antigens (en, replaced) Class I Histocompatibility Antigens (en, replaced) Class I Human Antigens (en, replaced) Class I Antigens (en, replaced) X
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