ONKI3 | Medical Subject Headings

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Uroporphyrinogen Decarboxylase

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Hierarchy:	Medical Subject Headings (MeSH) ∟ Enzymes and Coenzymes ∟ Enzymes ∟ Lyases ∟ Carbon-Carbon Lyases ∟ Carboxy-Lyases ∟ Uroporphyrinogen Decarboxylase 14 coordinate concepts ∟ Adenosylmethionine Decarboxylase \| ∟ Aromatic-L-Amino-Acid Decarboxylases \| ∟ Glutamate Decarboxylase \| ∟ Histidine Decarboxylase \| ∟ Indole-3-Glycerol-Phosphate Synthase \| ∟ Methylmalonyl-CoA Decarboxylase \| ∟ Ornithine Decarboxylase \| ∟ Orotidine-5'-Phosphate Decarboxylase \| ∟ Phosphoenolpyruvate Carboxykinase (ATP) \| ∟ Phosphoenolpyruvate Carboxykinase (GTP) \| ∟ Phosphoenolpyruvate Carboxylase \| ∟ Pyruvate Decarboxylase \| ∟ Ribulose-Bisphosphate Carboxylase \| ∟ Tyrosine Decarboxylase X
Broader terms:	Medical Subject Headings (MeSH) ∟ Enzymes and Coenzymes ∟ Enzymes ∟ Lyases ∟ Carbon-Carbon Lyases ∟ Carboxy-Lyases ∟ Uroporphyrinogen Decarboxylase Carboxy-Lyases > Carbon-Carbon Lyases > Lyases > Enzymes > Enzymes and Coenzymes > Medical Subject Headings (MeSH) X
Annotation:	/defic permitted but consider also PORPHYRIA CUTANEA TARDA and HEPATOERYTHROPOIETIC PORPHYRIA X
History note:	Carboxy-Lyases (1974-1975) \| Porphyrinogens (1975) \| Porphyrins (1974)X
historyNote*:	91(76); was see under CARBOXY-LYASES 1976-90 X
publicMeSHNote*:	91; was see under CARBOXY-LYASES 1976-90 X
Scope note:	An enzyme that catalyzes the decarboxylation of UROPORPHYRINOGEN III to coproporphyrinogen III by the conversion of four acetate groups to four methyl groups. It is the fifth enzyme in the 8-enzyme biosynthetic pathway of HEME. Several forms of cutaneous PORPHYRIAS are results of this enzyme deficiency as in PORPHYRIA CUTANEA TARDA; and HEPATOERYTHROPOIETIC PORPHYRIA. X
activeMeSHYear*:	2005 \| 2006 \| 2006A \| 2007X
dateCreated*:	1975-07-25X
dateEstablished*:	1991-01-01X
dateRevised*:	2005-07-12X
recordAuthorizer*:	agsX
recordMaintainer*:	agsX
recordOriginator*:	RLSX
Type:	Concept X
Coordinate terms:	Adenosylmethionine Decarboxylase \| Aromatic-L-Amino-Acid Decarboxylases \| Glutamate Decarboxylase \| Histidine Decarboxylase \| Indole-3-Glycerol-Phosphate Synthase \| Methylmalonyl-CoA Decarboxylase \| Ornithine Decarboxylase \| Orotidine-5'-Phosphate Decarboxylase \| Phosphoenolpyruvate Carboxykinase (ATP) \| Phosphoenolpyruvate Carboxykinase (GTP) \| Phosphoenolpyruvate Carboxylase \| Pyruvate Decarboxylase \| Ribulose-Bisphosphate Carboxylase \| Tyrosine Decarboxylase X
URI:	X
Labels and equivalent concepts:	Uroporfyrinogeenidekarboksylaasi (fi) Uroporfyrinogen dekarboxylas (sv) Uroporphyrinogen III Decarboxylase (en, replaced) Uroporphyrinogen Carboxy-Lyase (en, replaced) X
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