ONKI3 | Medical Subject Headings

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Hierarchy:	Medical Subject Headings (MeSH) ∟ Heterocyclic Compounds ∟ Heterocyclic Compounds, 1-Ring ∟ Pyrimidines ∟ Trimethoprim 18 coordinate concepts 1 subordinate concept ∟ Trimethoprim-Sulfamethoxazole Combination ∟ Buspirone \| ∟ Dipyridamole \| ∟ Epirizole \| ∟ Fursultiamin \| ∟ Hexetidine \| ∟ Minoxidil \| ∟ Mopidamol \| ∟ Morantel \| ∟ Nicarbazin \| ∟ Oxypurinol \| ∟ Pyrantel \| ∟ Pyrimethamine \| ∟ Pyrimidine Nucleosides \| ∟ Pyrimidine Nucleotides \| ∟ Pyrimidinones \| ∟ Pyrithiamine \| ∟ Thiamine \| ∟ Trapidil X
Broader terms:	Medical Subject Headings (MeSH) ∟ Heterocyclic Compounds ∟ Heterocyclic Compounds, 1-Ring ∟ Pyrimidines ∟ Trimethoprim Pyrimidines > Heterocyclic Compounds, 1-Ring > Heterocyclic Compounds > Medical Subject Headings (MeSH) X
Narrower terms:	Trimethoprim-Sulfamethoxazole Combination X
Annotation:	consider TRIMETHOPRIM RESISTANCE for nonsusceptibility of bacteria X
History note:	Anti-Infective Agents (1966-1971) \| Folic Acid Antagonists (1966-1971) \| Pyrimidines (1966-1971)X
historyNote*:	74(72) X
publicMeSHNote*:	74 X
Scope note:	A pyrimidine inhibitor of dihydrofolate reductase, it is an antibacterial related to PYRIMETHAMINE. The interference with folic acid metabolism may cause a depression of hematopoiesis. It is potentiated by SULFONAMIDES and the TRIMETHOPRIM-SULFAMETHOXAZOLE COMBINATION is the form most often used. It is sometimes used alone as an antimalarial. TRIMETHOPRIM RESISTANCE has been reported. X
activeMeSHYear*:	2002 \| 2003 \| 2004 \| 2005 \| 2006 \| 2007X
dateCreated*:	1999-01-01X
dateEstablished*:	1974-01-01X
dateRevised*:	2001-07-25X
recordAuthorizer*:	sjnX
recordMaintainer*:	ssbX
recordOriginator*:	NLMX
Related term:	Trimethoprim Resistance X
Type:	Concept X
Coordinate terms:	Buspirone \| Dipyridamole \| Epirizole \| Fursultiamin \| Hexetidine \| Minoxidil \| Mopidamol \| Morantel \| Nicarbazin \| Oxypurinol \| Pyrantel \| Pyrimethamine \| Pyrimidine Nucleosides \| Pyrimidine Nucleotides \| Pyrimidinones \| Pyrithiamine \| Thiamine \| Trapidil X
URI:	X
Labels and equivalent concepts:	Trimetopriimi (fi) Trimetoprim (sv) Trimethoprimum (la-FI, replaced) X
Share:	X