ONKI3 | Medical Subject Headings

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The way property values are displayed: value/row values side by side

The way concept relations are shown: separately in hierarchy

Hypoxanthine Phosphoribosyltransferase

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Hierarchy:	Medical Subject Headings (MeSH) ∟ Enzymes and Coenzymes ∟ Enzymes ∟ Transferases ∟ Glycosyltransferases ∟ Pentosyltransferases ∟ Hypoxanthine Phosphoribosyltransferase 9 coordinate concepts ∟ Adenine Phosphoribosyltransferase \| ∟ ADP Ribose Transferases \| ∟ Amidophosphoribosyltransferase \| ∟ Anthranilate Phosphoribosyltransferase \| ∟ ATP Phosphoribosyltransferase \| ∟ Orotate Phosphoribosyltransferase \| ∟ Purine-Nucleoside Phosphorylase \| ∟ Thymidine Phosphorylase \| ∟ Uridine Phosphorylase X
Broader terms:	Medical Subject Headings (MeSH) ∟ Enzymes and Coenzymes ∟ Enzymes ∟ Transferases ∟ Glycosyltransferases ∟ Pentosyltransferases ∟ Hypoxanthine Phosphoribosyltransferase Pentosyltransferases > Glycosyltransferases > Transferases > Enzymes > Enzymes and Coenzymes > Medical Subject Headings (MeSH) X
Annotation:	/defic: consider also LESCH-NYHAN SYNDROME or GOUT; DF: note short X ref X
History note:	Pentosephosphates (1972-1974) \| Pentosyltransferases (1972-1974)X
historyNote*:	75; GUANINE PHOSPHORIBOSYLTRANSFERASE was GUANINE PHOSPHORIBOSYLTRANSFERASE (NM) 1978-91 X
onlineNote*:	use HYPOXANTHINE PHOSPHORIBOSYLTRANSFERASE (NM) to search GUANINE PHOSPHORIBOSYLTRANSFERASE (NM) 1980-91 X
publicMeSHNote*:	75; GUANINE PHOSPHORIBOSYLTRANSFERASE was indexed under PENTOSYLTRANSFERASES 1978-91 X
Scope note:	An enzyme that catalyzes the conversion of 5-phosphoribosyl-1-pyrophosphate and hypoxanthine, guanine, or 6-mercaptopurine to the corresponding 5'-mononucleotides and pyrophosphate. The enzyme is important in purine biosynthesis as well as central nervous system functions. Complete lack of enzyme activity is associated with the LESCH-NYHAN SYNDROME, while partial deficiency results in overproduction of uric acid. EC 2.4.2.8. X
activeMeSHYear*:	2004 \| 2005 \| 2006 \| 2007X
dateCreated*:	1974-11-11X
dateEstablished*:	1975-09-01X
dateRevised*:	2003-07-09X
recordAuthorizer*:	sjnX
recordMaintainer*:	ssbX
recordOriginator*:	NLMX
Related term:	Gout \| Lesch-Nyhan Syndrome X
Type:	Concept X
Coordinate terms:	Adenine Phosphoribosyltransferase \| ADP Ribose Transferases \| Amidophosphoribosyltransferase \| Anthranilate Phosphoribosyltransferase \| ATP Phosphoribosyltransferase \| Orotate Phosphoribosyltransferase \| Purine-Nucleoside Phosphorylase \| Thymidine Phosphorylase \| Uridine Phosphorylase X
URI:	X
Labels and equivalent concepts:	Hypoksantiinifosforibosyylitransferaasi (fi) Hypoxantinfosforibosyltransferas (sv) Hypoxanthine-Guanine Phosphoribosyltransferase (en, replaced) IMP Pyrophosphorylase (en, replaced) HPRTase (en, replaced) HPRT (en, replaced) HGPRT (en, replaced) Guanine Phosphoribosyltransferase (en, replaced) X
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