ONKI3 | Medical Subject Headings

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Glutamate Decarboxylase

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Hierarchy:	Medical Subject Headings (MeSH) ∟ Enzymes and Coenzymes ∟ Enzymes ∟ Lyases ∟ Carbon-Carbon Lyases ∟ Carboxy-Lyases ∟ Glutamate Decarboxylase 14 coordinate concepts ∟ Adenosylmethionine Decarboxylase \| ∟ Aromatic-L-Amino-Acid Decarboxylases \| ∟ Histidine Decarboxylase \| ∟ Indole-3-Glycerol-Phosphate Synthase \| ∟ Methylmalonyl-CoA Decarboxylase \| ∟ Ornithine Decarboxylase \| ∟ Orotidine-5'-Phosphate Decarboxylase \| ∟ Phosphoenolpyruvate Carboxykinase (ATP) \| ∟ Phosphoenolpyruvate Carboxykinase (GTP) \| ∟ Phosphoenolpyruvate Carboxylase \| ∟ Pyruvate Decarboxylase \| ∟ Ribulose-Bisphosphate Carboxylase \| ∟ Tyrosine Decarboxylase \| ∟ Uroporphyrinogen Decarboxylase X
Broader terms:	Medical Subject Headings (MeSH) ∟ Enzymes and Coenzymes ∟ Enzymes ∟ Lyases ∟ Carbon-Carbon Lyases ∟ Carboxy-Lyases ∟ Glutamate Decarboxylase Carboxy-Lyases > Carbon-Carbon Lyases > Lyases > Enzymes > Enzymes and Coenzymes > Medical Subject Headings (MeSH) X
History note:	Carboxy-Lyases (1973-1974) \| Glutamates (1973-1974)X
historyNote*:	84(75); was see under CARBOXY-LYASES 1975-83 X
publicMeSHNote*:	84; was see under CARBOXY-LYASES 1975-83 X
Scope note:	A pyridoxal-phosphate protein that catalyzes the alpha-decarboxylation of L-glutamic acid to form gamma-aminobutyric acid and carbon dioxide. The enzyme is found in bacteria and in invertebrate and vertebrate nervous systems. It is the rate-limiting enzyme in determining GAMMA-AMINOBUTYRIC ACID levels in normal nervous tissues. The brain enzyme also acts on L-cysteate, L-cysteine sulfinate, and L-aspartate. EC 4.1.1.15. X
activeMeSHYear*:	2004 \| 2005 \| 2006 \| 2007X
dateCreated*:	1974-11-19X
dateEstablished*:	1984-01-01X
dateRevised*:	2003-07-09X
recordAuthorizer*:	sjnX
recordMaintainer*:	ssbX
recordOriginator*:	NLMX
Type:	Concept X
Coordinate terms:	Adenosylmethionine Decarboxylase \| Aromatic-L-Amino-Acid Decarboxylases \| Histidine Decarboxylase \| Indole-3-Glycerol-Phosphate Synthase \| Methylmalonyl-CoA Decarboxylase \| Ornithine Decarboxylase \| Orotidine-5'-Phosphate Decarboxylase \| Phosphoenolpyruvate Carboxykinase (ATP) \| Phosphoenolpyruvate Carboxykinase (GTP) \| Phosphoenolpyruvate Carboxylase \| Pyruvate Decarboxylase \| Ribulose-Bisphosphate Carboxylase \| Tyrosine Decarboxylase \| Uroporphyrinogen Decarboxylase X
URI:	X
Labels and equivalent concepts:	Glutamaattidekarboksylaasi (fi) GAD (fi, replaced) Glutamatdekarboxylas (sv) Glutamic Acid Decarboxylase (en, replaced) Glutamate Carboxy-Lyase (en, replaced) X
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