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The way concept relations are shown:
Dextromethorphan
Hierarchy: | ∟ ∟ ∟ ∟ ∟ ∟ Dextromethorphan ∟ ∟ ∟ ∟ ∟ Dextromethorphan ∟ ∟ ∟ ∟ ∟ Dextromethorphan ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ Dextromethorphan ∟ ∟ ∟ ∟ ∟ ∟ Dextromethorphan X |
Broader terms: | ∟ ∟ ∟ ∟ ∟ ∟ Dextromethorphan ∟ ∟ ∟ ∟ ∟ Dextromethorphan ∟ ∟ ∟ ∟ ∟ Dextromethorphan ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ Dextromethorphan ∟ ∟ ∟ ∟ ∟ ∟ Dextromethorphan |
History note: | |
historyNote*: | 91(72); was see under LEVORPHANOL 1972-90
X |
publicMeSHNote*: | 91; was see under LEVORPHANOL 1972-90
X |
Scope note: | The d-isomer of the codeine analog of LEVORPHANOL. Dextromethorphan shows high affinity binding to several regions of the brain, including the medullary cough center. This compound is an NMDA receptor antagonist (RECEPTORS, N-METHYL-D-ASPARTATE) and acts as a non-competitive channel blocker. It is one of the widely used ANTITUSSIVES, and is also used to study the involvement of glutamate receptors in neurotoxicity.
X |
activeMeSHYear*: | 2007X |
dateCreated*: | 1999-01-01X |
dateEstablished*: | 1991-01-01X |
dateRevised*: | 2006-07-05X |
recordAuthorizer*: | sjnX |
recordMaintainer*: | ssbX |
recordOriginator*: | NLMX |
Type: | |
URI: | |
Labels and equivalent concepts: | Dekstrometorfaani (fi) XDextrometorfan (sv) d-Methorphan (en, replaced) |
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