ONKI3 | Medical Subject Headings

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Hierarchy:	Medical Subject Headings (MeSH) ∟ Amino Acids, Peptides, and Proteins ∟ Amino Acids ∟ Amino Acids, Cyclic ∟ Imino Acids ∟ Proline ∟ Captopril 2 coordinate concepts ∟ Fosinopril \| ∟ Hydroxyproline Medical Subject Headings (MeSH) ∟ Organic Chemicals ∟ Carboxylic Acids ∟ Acids, Acyclic ∟ Imino Acids ∟ Proline ∟ Captopril 2 coordinate concepts ∟ Fosinopril \| ∟ Hydroxyproline Medical Subject Headings (MeSH) ∟ Organic Chemicals ∟ Imines ∟ Imino Acids ∟ Proline ∟ Captopril 2 coordinate concepts ∟ Fosinopril \| ∟ Hydroxyproline X
Broader terms:	Medical Subject Headings (MeSH) ∟ Amino Acids, Peptides, and Proteins ∟ Amino Acids ∟ Amino Acids, Cyclic ∟ Imino Acids ∟ Proline ∟ Captopril Medical Subject Headings (MeSH) ∟ Organic Chemicals ∟ Carboxylic Acids ∟ Acids, Acyclic ∟ Imino Acids ∟ Proline ∟ Captopril Medical Subject Headings (MeSH) ∟ Organic Chemicals ∟ Imines ∟ Imino Acids ∟ Proline ∟ Captopril Proline > Imino Acids > Amino Acids, Cyclic > Amino Acids > Amino Acids, Peptides, and Proteins > Medical Subject Headings (MeSH) Proline > Imino Acids > Acids, Acyclic > Carboxylic Acids > Organic Chemicals > Medical Subject Headings (MeSH) Proline > Imino Acids > Imines > Organic Chemicals > Medical Subject Headings (MeSH) X
History note:	Kininase II/antagonists & inhibitors (1973-1979) \| Peptide Peptidohydrolases (1966-1967) /antagonists & inhibitors (1968-1972) \| Proline (1966-1974) /antagonists & inhibitors (1975-1979)X
historyNote*:	86(80); was see under PROLINE 1980-85; SQ 14225 was see CAPTOPRIL 1980-93 X
onlineNote*:	use CAPTOPRIL to search SQ 14225 1980-93 X
publicMeSHNote*:	86; was see under PROLINE 1980-85; SQ 14225 was see CAPTOPRIL 1980-93 X
Scope note:	A potent and specific inhibitor of PEPTIDYL-DIPEPTIDASE A. It blocks the conversion of ANGIOTENSIN I to ANGIOTENSIN II, a vasoconstrictor and important regulator of arterial blood pressure. Captopril acts to suppress the RENIN-ANGIOTENSIN SYSTEM and inhibits pressure responses to exogenous angiotensin. X
activeMeSHYear*:	2000 \| 2000A \| 2000B \| 2001 \| 2002 \| 2003 \| 2004 \| 2005 \| 2006 \| 2007X
dateCreated*:	1979-05-23X
dateEstablished*:	1986-01-01X
dateRevised*:	2000-01-19X
recordAuthorizer*:	agsX
recordMaintainer*:	agsX
recordOriginator*:	RLSX
Type:	Concept X
Coordinate terms:	Fosinopril \| Hydroxyproline X
URI:	X
Labels and equivalent concepts:	Kaptopriili (fi) Kaptopril (sv) Capoten (sv, replaced) SQ-14534 (en, replaced) SQ-14225 (en, replaced) (S)-1-(3-Mercapto-2-methyl-1-oxopropyl)-L-proline (en, replaced) X
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