ONKI3 | MedIEQ: Medical Subject Headings

The ONKI is provided as a part of the ONKI Living Lab - an open lab for testing the latest semantic web technologies in practice, with real users like you. Currently, over 10 000 people are using ONKI each month.

We hope you like the ONKI service and enjoy using it for your purposes!

If you encounter any problems or have improvement ideas, please contact the ONKI team. We are also very much interested in your success stories in using ONKI - please share your experiences!

The ONKI Team

Jouni Tuominen, Living Lab contact person, APIs, widgets, publishing of ontologies, etc.
Eero Hyvönen, professor, head of research group

Former members: Kim Viljanen, Rami Alatalo.

Building the future of the Semantic Web and beyond.

SeCo's homepage
For the latest semantic news, follow us on Twitter and fan us on Facebook!

How can we help you?

Live presentations about ONKI: what it is? how to use it?
Support for creating and publishing ontologies.
Online technical support for using ONKI.
Co-operation in projects.
And more, please ask.

suomeksi på svenska in English

The way property values are displayed: value/row values side by side

The way concept relations are shown: separately in hierarchy

Adrenoleukodystrophy

Loading results...


Hierarchy:	Medical Subject Headings (MeSH) ∟ Behavior and Behavior Mechanisms ∟ Neurobehavioral Manifestations ∟ Mental Retardation ∟ Mental Retardation, X-Linked ∟ Adrenoleukodystrophy 22 coordinate concepts ∟ Alexander Disease \| ∟ Canavan Disease \| ∟ Leukodystrophy, Globoid Cell \| ∟ Leukodystrophy, Metachromatic \| ∟ Pelizaeus-Merzbacher Disease \| ∟ Addison Disease \| ∟ Hypoaldosteronism \| ∟ Pseudohypoaldosteronism \| ∟ Waterhouse-Friderichsen Syndrome \| ∟ Coffin-Lowry Syndrome \| ∟ Fragile X Syndrome \| ∟ Glycogen Storage Disease Type IIb \| ∟ Lesch-Nyhan Syndrome \| ∟ Menkes Kinky Hair Syndrome \| ∟ Mucopolysaccharidosis II \| ∟ Pyruvate Dehydrogenase Complex Deficiency Disease \| ∟ Rett Syndrome \| ∟ Acatalasia \| ∟ Chondrodysplasia Punctata, Rhizomelic \| ∟ Refsum Disease \| ∟ Refsum Disease, Infantile \| ∟ Zellweger Syndrome Medical Subject Headings (MeSH) ∟ Congenital, Hereditary, and Neonatal Diseases and Abnormalities ∟ Genetic Diseases, Inborn ∟ Genetic Diseases, X-Linked ∟ Mental Retardation, X-Linked ∟ Adrenoleukodystrophy 22 coordinate concepts ∟ Alexander Disease \| ∟ Canavan Disease \| ∟ Leukodystrophy, Globoid Cell \| ∟ Leukodystrophy, Metachromatic \| ∟ Pelizaeus-Merzbacher Disease \| ∟ Addison Disease \| ∟ Hypoaldosteronism \| ∟ Pseudohypoaldosteronism \| ∟ Waterhouse-Friderichsen Syndrome \| ∟ Coffin-Lowry Syndrome \| ∟ Fragile X Syndrome \| ∟ Glycogen Storage Disease Type IIb \| ∟ Lesch-Nyhan Syndrome \| ∟ Menkes Kinky Hair Syndrome \| ∟ Mucopolysaccharidosis II \| ∟ Pyruvate Dehydrogenase Complex Deficiency Disease \| ∟ Rett Syndrome \| ∟ Acatalasia \| ∟ Chondrodysplasia Punctata, Rhizomelic \| ∟ Refsum Disease \| ∟ Refsum Disease, Infantile \| ∟ Zellweger Syndrome Medical Subject Headings (MeSH) ∟ Congenital, Hereditary, and Neonatal Diseases and Abnormalities ∟ Genetic Diseases, Inborn ∟ Heredodegenerative Disorders, Nervous System ∟ Hereditary Central Nervous System Demyelinating Diseases ∟ Adrenoleukodystrophy 22 coordinate concepts ∟ Alexander Disease \| ∟ Canavan Disease \| ∟ Leukodystrophy, Globoid Cell \| ∟ Leukodystrophy, Metachromatic \| ∟ Pelizaeus-Merzbacher Disease \| ∟ Addison Disease \| ∟ Hypoaldosteronism \| ∟ Pseudohypoaldosteronism \| ∟ Waterhouse-Friderichsen Syndrome \| ∟ Coffin-Lowry Syndrome \| ∟ Fragile X Syndrome \| ∟ Glycogen Storage Disease Type IIb \| ∟ Lesch-Nyhan Syndrome \| ∟ Menkes Kinky Hair Syndrome \| ∟ Mucopolysaccharidosis II \| ∟ Pyruvate Dehydrogenase Complex Deficiency Disease \| ∟ Rett Syndrome \| ∟ Acatalasia \| ∟ Chondrodysplasia Punctata, Rhizomelic \| ∟ Refsum Disease \| ∟ Refsum Disease, Infantile \| ∟ Zellweger Syndrome Medical Subject Headings (MeSH) ∟ Congenital, Hereditary, and Neonatal Diseases and Abnormalities ∟ Genetic Diseases, Inborn ∟ Heredodegenerative Disorders, Nervous System ∟ Mental Retardation, X-Linked ∟ Adrenoleukodystrophy 22 coordinate concepts ∟ Alexander Disease \| ∟ Canavan Disease \| ∟ Leukodystrophy, Globoid Cell \| ∟ Leukodystrophy, Metachromatic \| ∟ Pelizaeus-Merzbacher Disease \| ∟ Addison Disease \| ∟ Hypoaldosteronism \| ∟ Pseudohypoaldosteronism \| ∟ Waterhouse-Friderichsen Syndrome \| ∟ Coffin-Lowry Syndrome \| ∟ Fragile X Syndrome \| ∟ Glycogen Storage Disease Type IIb \| ∟ Lesch-Nyhan Syndrome \| ∟ Menkes Kinky Hair Syndrome \| ∟ Mucopolysaccharidosis II \| ∟ Pyruvate Dehydrogenase Complex Deficiency Disease \| ∟ Rett Syndrome \| ∟ Acatalasia \| ∟ Chondrodysplasia Punctata, Rhizomelic \| ∟ Refsum Disease \| ∟ Refsum Disease, Infantile \| ∟ Zellweger Syndrome Medical Subject Headings (MeSH) ∟ Congenital, Hereditary, and Neonatal Diseases and Abnormalities ∟ Genetic Diseases, Inborn ∟ Metabolism, Inborn Errors ∟ Brain Diseases, Metabolic, Inborn ∟ Peroxisomal Disorders ∟ Adrenoleukodystrophy 22 coordinate concepts ∟ Alexander Disease \| ∟ Canavan Disease \| ∟ Leukodystrophy, Globoid Cell \| ∟ Leukodystrophy, Metachromatic \| ∟ Pelizaeus-Merzbacher Disease \| ∟ Addison Disease \| ∟ Hypoaldosteronism \| ∟ Pseudohypoaldosteronism \| ∟ Waterhouse-Friderichsen Syndrome \| ∟ Coffin-Lowry Syndrome \| ∟ Fragile X Syndrome \| ∟ Glycogen Storage Disease Type IIb \| ∟ Lesch-Nyhan Syndrome \| ∟ Menkes Kinky Hair Syndrome \| ∟ Mucopolysaccharidosis II \| ∟ Pyruvate Dehydrogenase Complex Deficiency Disease \| ∟ Rett Syndrome \| ∟ Acatalasia \| ∟ Chondrodysplasia Punctata, Rhizomelic \| ∟ Refsum Disease \| ∟ Refsum Disease, Infantile \| ∟ Zellweger Syndrome Medical Subject Headings (MeSH) ∟ Congenital, Hereditary, and Neonatal Diseases and Abnormalities ∟ Genetic Diseases, Inborn ∟ Metabolism, Inborn Errors ∟ Peroxisomal Disorders ∟ Adrenoleukodystrophy 22 coordinate concepts ∟ Alexander Disease \| ∟ Canavan Disease \| ∟ Leukodystrophy, Globoid Cell \| ∟ Leukodystrophy, Metachromatic \| ∟ Pelizaeus-Merzbacher Disease \| ∟ Addison Disease \| ∟ Hypoaldosteronism \| ∟ Pseudohypoaldosteronism \| ∟ Waterhouse-Friderichsen Syndrome \| ∟ Coffin-Lowry Syndrome \| ∟ Fragile X Syndrome \| ∟ Glycogen Storage Disease Type IIb \| ∟ Lesch-Nyhan Syndrome \| ∟ Menkes Kinky Hair Syndrome \| ∟ Mucopolysaccharidosis II \| ∟ Pyruvate Dehydrogenase Complex Deficiency Disease \| ∟ Rett Syndrome \| ∟ Acatalasia \| ∟ Chondrodysplasia Punctata, Rhizomelic \| ∟ Refsum Disease \| ∟ Refsum Disease, Infantile \| ∟ Zellweger Syndrome Medical Subject Headings (MeSH) ∟ Endocrine System Diseases ∟ Adrenal Gland Diseases ∟ Adrenal Insufficiency ∟ Adrenoleukodystrophy 22 coordinate concepts ∟ Alexander Disease \| ∟ Canavan Disease \| ∟ Leukodystrophy, Globoid Cell \| ∟ Leukodystrophy, Metachromatic \| ∟ Pelizaeus-Merzbacher Disease \| ∟ Addison Disease \| ∟ Hypoaldosteronism \| ∟ Pseudohypoaldosteronism \| ∟ Waterhouse-Friderichsen Syndrome \| ∟ Coffin-Lowry Syndrome \| ∟ Fragile X Syndrome \| ∟ Glycogen Storage Disease Type IIb \| ∟ Lesch-Nyhan Syndrome \| ∟ Menkes Kinky Hair Syndrome \| ∟ Mucopolysaccharidosis II \| ∟ Pyruvate Dehydrogenase Complex Deficiency Disease \| ∟ Rett Syndrome \| ∟ Acatalasia \| ∟ Chondrodysplasia Punctata, Rhizomelic \| ∟ Refsum Disease \| ∟ Refsum Disease, Infantile \| ∟ Zellweger Syndrome Medical Subject Headings (MeSH) ∟ Mental Disorders ∟ Mental Disorders Diagnosed in Childhood ∟ Mental Retardation ∟ Mental Retardation, X-Linked ∟ Adrenoleukodystrophy 22 coordinate concepts ∟ Alexander Disease \| ∟ Canavan Disease \| ∟ Leukodystrophy, Globoid Cell \| ∟ Leukodystrophy, Metachromatic \| ∟ Pelizaeus-Merzbacher Disease \| ∟ Addison Disease \| ∟ Hypoaldosteronism \| ∟ Pseudohypoaldosteronism \| ∟ Waterhouse-Friderichsen Syndrome \| ∟ Coffin-Lowry Syndrome \| ∟ Fragile X Syndrome \| ∟ Glycogen Storage Disease Type IIb \| ∟ Lesch-Nyhan Syndrome \| ∟ Menkes Kinky Hair Syndrome \| ∟ Mucopolysaccharidosis II \| ∟ Pyruvate Dehydrogenase Complex Deficiency Disease \| ∟ Rett Syndrome \| ∟ Acatalasia \| ∟ Chondrodysplasia Punctata, Rhizomelic \| ∟ Refsum Disease \| ∟ Refsum Disease, Infantile \| ∟ Zellweger Syndrome Medical Subject Headings (MeSH) ∟ Nervous System Diseases ∟ Central Nervous System Diseases ∟ Brain Diseases ∟ Brain Diseases, Metabolic ∟ Brain Diseases, Metabolic, Inborn ∟ Peroxisomal Disorders ∟ Adrenoleukodystrophy 22 coordinate concepts ∟ Alexander Disease \| ∟ Canavan Disease \| ∟ Leukodystrophy, Globoid Cell \| ∟ Leukodystrophy, Metachromatic \| ∟ Pelizaeus-Merzbacher Disease \| ∟ Addison Disease \| ∟ Hypoaldosteronism \| ∟ Pseudohypoaldosteronism \| ∟ Waterhouse-Friderichsen Syndrome \| ∟ Coffin-Lowry Syndrome \| ∟ Fragile X Syndrome \| ∟ Glycogen Storage Disease Type IIb \| ∟ Lesch-Nyhan Syndrome \| ∟ Menkes Kinky Hair Syndrome \| ∟ Mucopolysaccharidosis II \| ∟ Pyruvate Dehydrogenase Complex Deficiency Disease \| ∟ Rett Syndrome \| ∟ Acatalasia \| ∟ Chondrodysplasia Punctata, Rhizomelic \| ∟ Refsum Disease \| ∟ Refsum Disease, Infantile \| ∟ Zellweger Syndrome Medical Subject Headings (MeSH) ∟ Nervous System Diseases ∟ Demyelinating Diseases ∟ Hereditary Central Nervous System Demyelinating Diseases ∟ Adrenoleukodystrophy 22 coordinate concepts ∟ Alexander Disease \| ∟ Canavan Disease \| ∟ Leukodystrophy, Globoid Cell \| ∟ Leukodystrophy, Metachromatic \| ∟ Pelizaeus-Merzbacher Disease \| ∟ Addison Disease \| ∟ Hypoaldosteronism \| ∟ Pseudohypoaldosteronism \| ∟ Waterhouse-Friderichsen Syndrome \| ∟ Coffin-Lowry Syndrome \| ∟ Fragile X Syndrome \| ∟ Glycogen Storage Disease Type IIb \| ∟ Lesch-Nyhan Syndrome \| ∟ Menkes Kinky Hair Syndrome \| ∟ Mucopolysaccharidosis II \| ∟ Pyruvate Dehydrogenase Complex Deficiency Disease \| ∟ Rett Syndrome \| ∟ Acatalasia \| ∟ Chondrodysplasia Punctata, Rhizomelic \| ∟ Refsum Disease \| ∟ Refsum Disease, Infantile \| ∟ Zellweger Syndrome Medical Subject Headings (MeSH) ∟ Nervous System Diseases ∟ Neurodegenerative Diseases ∟ Heredodegenerative Disorders, Nervous System ∟ Hereditary Central Nervous System Demyelinating Diseases ∟ Adrenoleukodystrophy 22 coordinate concepts ∟ Alexander Disease \| ∟ Canavan Disease \| ∟ Leukodystrophy, Globoid Cell \| ∟ Leukodystrophy, Metachromatic \| ∟ Pelizaeus-Merzbacher Disease \| ∟ Addison Disease \| ∟ Hypoaldosteronism \| ∟ Pseudohypoaldosteronism \| ∟ Waterhouse-Friderichsen Syndrome \| ∟ Coffin-Lowry Syndrome \| ∟ Fragile X Syndrome \| ∟ Glycogen Storage Disease Type IIb \| ∟ Lesch-Nyhan Syndrome \| ∟ Menkes Kinky Hair Syndrome \| ∟ Mucopolysaccharidosis II \| ∟ Pyruvate Dehydrogenase Complex Deficiency Disease \| ∟ Rett Syndrome \| ∟ Acatalasia \| ∟ Chondrodysplasia Punctata, Rhizomelic \| ∟ Refsum Disease \| ∟ Refsum Disease, Infantile \| ∟ Zellweger Syndrome Medical Subject Headings (MeSH) ∟ Nervous System Diseases ∟ Neurodegenerative Diseases ∟ Heredodegenerative Disorders, Nervous System ∟ Mental Retardation, X-Linked ∟ Adrenoleukodystrophy 22 coordinate concepts ∟ Alexander Disease \| ∟ Canavan Disease \| ∟ Leukodystrophy, Globoid Cell \| ∟ Leukodystrophy, Metachromatic \| ∟ Pelizaeus-Merzbacher Disease \| ∟ Addison Disease \| ∟ Hypoaldosteronism \| ∟ Pseudohypoaldosteronism \| ∟ Waterhouse-Friderichsen Syndrome \| ∟ Coffin-Lowry Syndrome \| ∟ Fragile X Syndrome \| ∟ Glycogen Storage Disease Type IIb \| ∟ Lesch-Nyhan Syndrome \| ∟ Menkes Kinky Hair Syndrome \| ∟ Mucopolysaccharidosis II \| ∟ Pyruvate Dehydrogenase Complex Deficiency Disease \| ∟ Rett Syndrome \| ∟ Acatalasia \| ∟ Chondrodysplasia Punctata, Rhizomelic \| ∟ Refsum Disease \| ∟ Refsum Disease, Infantile \| ∟ Zellweger Syndrome Medical Subject Headings (MeSH) ∟ Nervous System Diseases ∟ Neurologic Manifestations ∟ Neurobehavioral Manifestations ∟ Mental Retardation ∟ Mental Retardation, X-Linked ∟ Adrenoleukodystrophy 22 coordinate concepts ∟ Alexander Disease \| ∟ Canavan Disease \| ∟ Leukodystrophy, Globoid Cell \| ∟ Leukodystrophy, Metachromatic \| ∟ Pelizaeus-Merzbacher Disease \| ∟ Addison Disease \| ∟ Hypoaldosteronism \| ∟ Pseudohypoaldosteronism \| ∟ Waterhouse-Friderichsen Syndrome \| ∟ Coffin-Lowry Syndrome \| ∟ Fragile X Syndrome \| ∟ Glycogen Storage Disease Type IIb \| ∟ Lesch-Nyhan Syndrome \| ∟ Menkes Kinky Hair Syndrome \| ∟ Mucopolysaccharidosis II \| ∟ Pyruvate Dehydrogenase Complex Deficiency Disease \| ∟ Rett Syndrome \| ∟ Acatalasia \| ∟ Chondrodysplasia Punctata, Rhizomelic \| ∟ Refsum Disease \| ∟ Refsum Disease, Infantile \| ∟ Zellweger Syndrome Medical Subject Headings (MeSH) ∟ Nutritional and Metabolic Diseases ∟ Metabolic Diseases ∟ Brain Diseases, Metabolic ∟ Brain Diseases, Metabolic, Inborn ∟ Peroxisomal Disorders ∟ Adrenoleukodystrophy 22 coordinate concepts ∟ Alexander Disease \| ∟ Canavan Disease \| ∟ Leukodystrophy, Globoid Cell \| ∟ Leukodystrophy, Metachromatic \| ∟ Pelizaeus-Merzbacher Disease \| ∟ Addison Disease \| ∟ Hypoaldosteronism \| ∟ Pseudohypoaldosteronism \| ∟ Waterhouse-Friderichsen Syndrome \| ∟ Coffin-Lowry Syndrome \| ∟ Fragile X Syndrome \| ∟ Glycogen Storage Disease Type IIb \| ∟ Lesch-Nyhan Syndrome \| ∟ Menkes Kinky Hair Syndrome \| ∟ Mucopolysaccharidosis II \| ∟ Pyruvate Dehydrogenase Complex Deficiency Disease \| ∟ Rett Syndrome \| ∟ Acatalasia \| ∟ Chondrodysplasia Punctata, Rhizomelic \| ∟ Refsum Disease \| ∟ Refsum Disease, Infantile \| ∟ Zellweger Syndrome Medical Subject Headings (MeSH) ∟ Nutritional and Metabolic Diseases ∟ Metabolic Diseases ∟ Metabolism, Inborn Errors ∟ Brain Diseases, Metabolic, Inborn ∟ Peroxisomal Disorders ∟ Adrenoleukodystrophy 22 coordinate concepts ∟ Alexander Disease \| ∟ Canavan Disease \| ∟ Leukodystrophy, Globoid Cell \| ∟ Leukodystrophy, Metachromatic \| ∟ Pelizaeus-Merzbacher Disease \| ∟ Addison Disease \| ∟ Hypoaldosteronism \| ∟ Pseudohypoaldosteronism \| ∟ Waterhouse-Friderichsen Syndrome \| ∟ Coffin-Lowry Syndrome \| ∟ Fragile X Syndrome \| ∟ Glycogen Storage Disease Type IIb \| ∟ Lesch-Nyhan Syndrome \| ∟ Menkes Kinky Hair Syndrome \| ∟ Mucopolysaccharidosis II \| ∟ Pyruvate Dehydrogenase Complex Deficiency Disease \| ∟ Rett Syndrome \| ∟ Acatalasia \| ∟ Chondrodysplasia Punctata, Rhizomelic \| ∟ Refsum Disease \| ∟ Refsum Disease, Infantile \| ∟ Zellweger Syndrome Medical Subject Headings (MeSH) ∟ Nutritional and Metabolic Diseases ∟ Metabolic Diseases ∟ Metabolism, Inborn Errors ∟ Peroxisomal Disorders ∟ Adrenoleukodystrophy 22 coordinate concepts ∟ Alexander Disease \| ∟ Canavan Disease \| ∟ Leukodystrophy, Globoid Cell \| ∟ Leukodystrophy, Metachromatic \| ∟ Pelizaeus-Merzbacher Disease \| ∟ Addison Disease \| ∟ Hypoaldosteronism \| ∟ Pseudohypoaldosteronism \| ∟ Waterhouse-Friderichsen Syndrome \| ∟ Coffin-Lowry Syndrome \| ∟ Fragile X Syndrome \| ∟ Glycogen Storage Disease Type IIb \| ∟ Lesch-Nyhan Syndrome \| ∟ Menkes Kinky Hair Syndrome \| ∟ Mucopolysaccharidosis II \| ∟ Pyruvate Dehydrogenase Complex Deficiency Disease \| ∟ Rett Syndrome \| ∟ Acatalasia \| ∟ Chondrodysplasia Punctata, Rhizomelic \| ∟ Refsum Disease \| ∟ Refsum Disease, Infantile \| ∟ Zellweger Syndrome Medical Subject Headings (MeSH) ∟ Pathological Conditions, Signs and Symptoms ∟ Signs and Symptoms ∟ Neurologic Manifestations ∟ Neurobehavioral Manifestations ∟ Mental Retardation ∟ Mental Retardation, X-Linked ∟ Adrenoleukodystrophy 22 coordinate concepts ∟ Alexander Disease \| ∟ Canavan Disease \| ∟ Leukodystrophy, Globoid Cell \| ∟ Leukodystrophy, Metachromatic \| ∟ Pelizaeus-Merzbacher Disease \| ∟ Addison Disease \| ∟ Hypoaldosteronism \| ∟ Pseudohypoaldosteronism \| ∟ Waterhouse-Friderichsen Syndrome \| ∟ Coffin-Lowry Syndrome \| ∟ Fragile X Syndrome \| ∟ Glycogen Storage Disease Type IIb \| ∟ Lesch-Nyhan Syndrome \| ∟ Menkes Kinky Hair Syndrome \| ∟ Mucopolysaccharidosis II \| ∟ Pyruvate Dehydrogenase Complex Deficiency Disease \| ∟ Rett Syndrome \| ∟ Acatalasia \| ∟ Chondrodysplasia Punctata, Rhizomelic \| ∟ Refsum Disease \| ∟ Refsum Disease, Infantile \| ∟ Zellweger Syndrome X
Broader terms:	Medical Subject Headings (MeSH) ∟ Behavior and Behavior Mechanisms ∟ Neurobehavioral Manifestations ∟ Mental Retardation ∟ Mental Retardation, X-Linked ∟ Adrenoleukodystrophy Medical Subject Headings (MeSH) ∟ Congenital, Hereditary, and Neonatal Diseases and Abnormalities ∟ Genetic Diseases, Inborn ∟ Genetic Diseases, X-Linked ∟ Mental Retardation, X-Linked ∟ Adrenoleukodystrophy Medical Subject Headings (MeSH) ∟ Congenital, Hereditary, and Neonatal Diseases and Abnormalities ∟ Genetic Diseases, Inborn ∟ Heredodegenerative Disorders, Nervous System ∟ Hereditary Central Nervous System Demyelinating Diseases ∟ Adrenoleukodystrophy Medical Subject Headings (MeSH) ∟ Congenital, Hereditary, and Neonatal Diseases and Abnormalities ∟ Genetic Diseases, Inborn ∟ Heredodegenerative Disorders, Nervous System ∟ Mental Retardation, X-Linked ∟ Adrenoleukodystrophy Medical Subject Headings (MeSH) ∟ Congenital, Hereditary, and Neonatal Diseases and Abnormalities ∟ Genetic Diseases, Inborn ∟ Metabolism, Inborn Errors ∟ Brain Diseases, Metabolic, Inborn ∟ Peroxisomal Disorders ∟ Adrenoleukodystrophy Medical Subject Headings (MeSH) ∟ Congenital, Hereditary, and Neonatal Diseases and Abnormalities ∟ Genetic Diseases, Inborn ∟ Metabolism, Inborn Errors ∟ Peroxisomal Disorders ∟ Adrenoleukodystrophy Medical Subject Headings (MeSH) ∟ Endocrine System Diseases ∟ Adrenal Gland Diseases ∟ Adrenal Insufficiency ∟ Adrenoleukodystrophy Medical Subject Headings (MeSH) ∟ Mental Disorders ∟ Mental Disorders Diagnosed in Childhood ∟ Mental Retardation ∟ Mental Retardation, X-Linked ∟ Adrenoleukodystrophy Medical Subject Headings (MeSH) ∟ Nervous System Diseases ∟ Central Nervous System Diseases ∟ Brain Diseases ∟ Brain Diseases, Metabolic ∟ Brain Diseases, Metabolic, Inborn ∟ Peroxisomal Disorders ∟ Adrenoleukodystrophy Medical Subject Headings (MeSH) ∟ Nervous System Diseases ∟ Demyelinating Diseases ∟ Hereditary Central Nervous System Demyelinating Diseases ∟ Adrenoleukodystrophy Medical Subject Headings (MeSH) ∟ Nervous System Diseases ∟ Neurodegenerative Diseases ∟ Heredodegenerative Disorders, Nervous System ∟ Hereditary Central Nervous System Demyelinating Diseases ∟ Adrenoleukodystrophy Medical Subject Headings (MeSH) ∟ Nervous System Diseases ∟ Neurodegenerative Diseases ∟ Heredodegenerative Disorders, Nervous System ∟ Mental Retardation, X-Linked ∟ Adrenoleukodystrophy Medical Subject Headings (MeSH) ∟ Nervous System Diseases ∟ Neurologic Manifestations ∟ Neurobehavioral Manifestations ∟ Mental Retardation ∟ Mental Retardation, X-Linked ∟ Adrenoleukodystrophy Medical Subject Headings (MeSH) ∟ Nutritional and Metabolic Diseases ∟ Metabolic Diseases ∟ Brain Diseases, Metabolic ∟ Brain Diseases, Metabolic, Inborn ∟ Peroxisomal Disorders ∟ Adrenoleukodystrophy Medical Subject Headings (MeSH) ∟ Nutritional and Metabolic Diseases ∟ Metabolic Diseases ∟ Metabolism, Inborn Errors ∟ Brain Diseases, Metabolic, Inborn ∟ Peroxisomal Disorders ∟ Adrenoleukodystrophy Medical Subject Headings (MeSH) ∟ Nutritional and Metabolic Diseases ∟ Metabolic Diseases ∟ Metabolism, Inborn Errors ∟ Peroxisomal Disorders ∟ Adrenoleukodystrophy Medical Subject Headings (MeSH) ∟ Pathological Conditions, Signs and Symptoms ∟ Signs and Symptoms ∟ Neurologic Manifestations ∟ Neurobehavioral Manifestations ∟ Mental Retardation ∟ Mental Retardation, X-Linked ∟ Adrenoleukodystrophy Mental Retardation, X-Linked > Mental Retardation > Neurobehavioral Manifestations > Behavior and Behavior Mechanisms > Medical Subject Headings (MeSH) Mental Retardation, X-Linked > Genetic Diseases, X-Linked > Genetic Diseases, Inborn > Congenital, Hereditary, and Neonatal Diseases and Abnormalities > Medical Subject Headings (MeSH) Hereditary Central Nervous System Demyelinating Diseases > Heredodegenerative Disorders, Nervous System > Genetic Diseases, Inborn > Congenital, Hereditary, and Neonatal Diseases and Abnormalities > Medical Subject Headings (MeSH) Mental Retardation, X-Linked > Heredodegenerative Disorders, Nervous System > Genetic Diseases, Inborn > Congenital, Hereditary, and Neonatal Diseases and Abnormalities > Medical Subject Headings (MeSH) Peroxisomal Disorders > Brain Diseases, Metabolic, Inborn > Metabolism, Inborn Errors > Genetic Diseases, Inborn > Congenital, Hereditary, and Neonatal Diseases and Abnormalities > Medical Subject Headings (MeSH) Peroxisomal Disorders > Metabolism, Inborn Errors > Genetic Diseases, Inborn > Congenital, Hereditary, and Neonatal Diseases and Abnormalities > Medical Subject Headings (MeSH) Adrenal Insufficiency > Adrenal Gland Diseases > Endocrine System Diseases > Medical Subject Headings (MeSH) Mental Retardation, X-Linked > Mental Retardation > Mental Disorders Diagnosed in Childhood > Mental Disorders > Medical Subject Headings (MeSH) Peroxisomal Disorders > Brain Diseases, Metabolic, Inborn > Brain Diseases, Metabolic > Brain Diseases > Central Nervous System Diseases > Nervous System Diseases > Medical Subject Headings (MeSH) Hereditary Central Nervous System Demyelinating Diseases > Demyelinating Diseases > Nervous System Diseases > Medical Subject Headings (MeSH) Hereditary Central Nervous System Demyelinating Diseases > Heredodegenerative Disorders, Nervous System > Neurodegenerative Diseases > Nervous System Diseases > Medical Subject Headings (MeSH) Mental Retardation, X-Linked > Heredodegenerative Disorders, Nervous System > Neurodegenerative Diseases > Nervous System Diseases > Medical Subject Headings (MeSH) Mental Retardation, X-Linked > Mental Retardation > Neurobehavioral Manifestations > Neurologic Manifestations > Nervous System Diseases > Medical Subject Headings (MeSH) Peroxisomal Disorders > Brain Diseases, Metabolic, Inborn > Brain Diseases, Metabolic > Metabolic Diseases > Nutritional and Metabolic Diseases > Medical Subject Headings (MeSH) Peroxisomal Disorders > Brain Diseases, Metabolic, Inborn > Metabolism, Inborn Errors > Metabolic Diseases > Nutritional and Metabolic Diseases > Medical Subject Headings (MeSH) Peroxisomal Disorders > Metabolism, Inborn Errors > Metabolic Diseases > Nutritional and Metabolic Diseases > Medical Subject Headings (MeSH) Mental Retardation, X-Linked > Mental Retardation > Neurobehavioral Manifestations > Neurologic Manifestations > Signs and Symptoms > Pathological Conditions, Signs and Symptoms > Medical Subject Headings (MeSH) X
Annotation:	do not confuse with ADRENOLEUKODYSTROPHY, NEONATAL see PEROXISOMAL DISORDERS X
History note:	Adrenal Gland Hypofunction (1968-1982) \| Cerebral Sclerosis, Diffuse (1966-1982) \| Demyelinating Diseases (1966-1982)X
historyNote*:	1991(1983) X
publicMeSHNote*:	1991; see CEREBRAL SCLEROSIS, DIFFUSE 1983-1990 X
Scope note:	An X-linked recessive disorder characterized by the accumulation of saturated very long chain fatty acids in the LYSOSOMES of ADRENAL CORTEX and the white matter of CENTRAL NERVOUS SYSTEM. This disease occurs almost exclusively in the males. Clinical features include the childhood onset of ATAXIA; NEUROBEHAVIORAL MANIFESTATIONS; HYPERPIGMENTATION; ADRENAL INSUFFICIENCY; SEIZURES; MUSCLE SPASTICITY; and DEMENTIA. The slowly progressive adult form is called adrenomyeloneuropathy. The defective gene ABCD1 is located at Xq28, and encodes the adrenoleukodystrophy protein (ATP-BINDING CASSETTE TRANSPORTERS). X
activeMeSHYear*:	2007X
dateCreated*:	1982-04-27X
dateEstablished*:	1991-01-01X
dateRevised*:	2006-07-05X
recordAuthorizer*:	sjnX
recordMaintainer*:	lktX
recordOriginator*:	RCX
Type:	Concept X
Coordinate terms:	Alexander Disease \| Canavan Disease \| Leukodystrophy, Globoid Cell \| Leukodystrophy, Metachromatic \| Pelizaeus-Merzbacher Disease \| Addison Disease \| Hypoaldosteronism \| Pseudohypoaldosteronism \| Waterhouse-Friderichsen Syndrome \| Coffin-Lowry Syndrome \| Fragile X Syndrome \| Glycogen Storage Disease Type IIb \| Lesch-Nyhan Syndrome \| Menkes Kinky Hair Syndrome \| Mucopolysaccharidosis II \| Pyruvate Dehydrogenase Complex Deficiency Disease \| Rett Syndrome \| Acatalasia \| Chondrodysplasia Punctata, Rhizomelic \| Refsum Disease \| Refsum Disease, Infantile \| Zellweger Syndrome X
URI:	X
Labels and equivalent concepts:	Adrenoleukodystrofia (fi) X-Linked Adrenoleukodystrophy (en, replaced) Schilder-Addison Complex (en, replaced) ALD (Adrenoleukodystrophy) (en, replaced) Adrenoleucodistrofia (es) Adrenoleukodystrophie (de) adrenoleukodystrofie (cs) Adrenoleucodistrofia Ligada a X (es, replaced) Adrenoleucodistrofia Ligada al X (es, replaced) Adrenomieloneuropatía (es, replaced) Complejo de Schilder-Addison (es, replaced) Schilder-Addison-Komplex (de, replaced) X-chromosomale Adrenoleukodystrophie (de, replaced) Adrenomyeloneuropathie (de, replaced) X
Share:	X