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The way concept relations are shown:
Transforming Growth Factor beta1
Hierarchy: | ∟ ∟ ∟ ∟ ∟ ∟ Transforming Growth Factor beta1 2 coordinate concepts1 subordinate concept∟ ∟ ∟ ∟ ∟ ∟ Transforming Growth Factor beta1 2 coordinate concepts1 subordinate concept∟ ∟ ∟ ∟ ∟ ∟ Transforming Growth Factor beta1 2 coordinate concepts1 subordinate concept∟ ∟ ∟ ∟ ∟ ∟ Transforming Growth Factor beta1 2 coordinate concepts1 subordinate concept∟ ∟ ∟ ∟ ∟ Transforming Growth Factor beta1 2 coordinate concepts1 subordinate concept∟ ∟ ∟ ∟ ∟ Transforming Growth Factor beta1 2 coordinate concepts1 subordinate conceptX |
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historyNote*: | 2007(1992)
X |
publicMeSHNote*: | 2007; TRANSFORMING GROWTH FACTOR BETA1 was indexed under TRANSFORMING GROWTH FACTOR 2000-2006; TRANSFORMING GROWTH FACTOR BETA 1 LATENCY ASSOCIATED PEPTIDE was indexed under TRANSFORMING GROWTH FACTOR 1992-2006; TRANSFORMING GROWTH FACTOR BETA I was indexed under PROTEINS 2005-2006
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Scope note: | A subtype of transforming growth factor beta that is synthesized by a wide variety of cells. It is synthesized as a precursor molecule that is cleaved to form mature TGF-beta 1 and TGF-beta1 latency-associated peptide. The association of the cleavage products results in the formation a latent protein which must be activated to bind its receptor. Defects in the gene that encodes TGF-beta1 are the cause of CAMURATI-ENGELMANN SYNDROME.
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activeMeSHYear*: | 2007X |
dateCreated*: | 2006-07-05X |
dateEstablished*: | 2007-01-01X |
recordAuthorizer*: | sjnX |
recordMaintainer*: | jmpX |
recordOriginator*: | jmpX |
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Labels and equivalent concepts: | TGF-beeta1 (fi) XTransforming Growth Factor beta I (en, replaced) TGF-beta1LAP (en, replaced) TGF-beta1 Latency-Associated Protein (en, replaced) TGF-beta1 (en, replaced) TGF-beta-1 (en, replaced) |
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