ONKI3 | Medical Subject Headings

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Nod2 Signaling Adaptor Protein

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Hierarchy:	Medical Subject Headings (MeSH) ∟ Amino Acids, Peptides, and Proteins ∟ Peptides ∟ Intracellular Signaling Peptides and Proteins ∟ Adaptor Proteins, Signal Transducing ∟ CARD Signaling Adaptor Proteins ∟ Nod2 Signaling Adaptor Protein 4 coordinate concepts ∟ Nod1 Signaling Adaptor Protein \| ∟ Apoptotic Protease-Activating Factor 1 \| ∟ CRADD Signaling Adaptor Protein \| ∟ Receptor-Interacting Protein Serine-Threonine Kinase 2 Medical Subject Headings (MeSH) ∟ Amino Acids, Peptides, and Proteins ∟ Peptides ∟ Intracellular Signaling Peptides and Proteins ∟ Adaptor Proteins, Signal Transducing ∟ Nod Signaling Adaptor Proteins ∟ Nod2 Signaling Adaptor Protein 4 coordinate concepts ∟ Nod1 Signaling Adaptor Protein \| ∟ Apoptotic Protease-Activating Factor 1 \| ∟ CRADD Signaling Adaptor Protein \| ∟ Receptor-Interacting Protein Serine-Threonine Kinase 2 Medical Subject Headings (MeSH) ∟ Amino Acids, Peptides, and Proteins ∟ Peptides ∟ Intracellular Signaling Peptides and Proteins ∟ Apoptosis Regulatory Proteins ∟ CARD Signaling Adaptor Proteins ∟ Nod2 Signaling Adaptor Protein 4 coordinate concepts ∟ Nod1 Signaling Adaptor Protein \| ∟ Apoptotic Protease-Activating Factor 1 \| ∟ CRADD Signaling Adaptor Protein \| ∟ Receptor-Interacting Protein Serine-Threonine Kinase 2 Medical Subject Headings (MeSH) ∟ Amino Acids, Peptides, and Proteins ∟ Proteins ∟ Carrier Proteins ∟ Adaptor Proteins, Signal Transducing ∟ CARD Signaling Adaptor Proteins ∟ Nod2 Signaling Adaptor Protein 4 coordinate concepts ∟ Nod1 Signaling Adaptor Protein \| ∟ Apoptotic Protease-Activating Factor 1 \| ∟ CRADD Signaling Adaptor Protein \| ∟ Receptor-Interacting Protein Serine-Threonine Kinase 2 Medical Subject Headings (MeSH) ∟ Amino Acids, Peptides, and Proteins ∟ Proteins ∟ Carrier Proteins ∟ Adaptor Proteins, Signal Transducing ∟ Nod Signaling Adaptor Proteins ∟ Nod2 Signaling Adaptor Protein 4 coordinate concepts ∟ Nod1 Signaling Adaptor Protein \| ∟ Apoptotic Protease-Activating Factor 1 \| ∟ CRADD Signaling Adaptor Protein \| ∟ Receptor-Interacting Protein Serine-Threonine Kinase 2 Medical Subject Headings (MeSH) ∟ Amino Acids, Peptides, and Proteins ∟ Proteins ∟ Intracellular Signaling Peptides and Proteins ∟ Adaptor Proteins, Signal Transducing ∟ CARD Signaling Adaptor Proteins ∟ Nod2 Signaling Adaptor Protein 4 coordinate concepts ∟ Nod1 Signaling Adaptor Protein \| ∟ Apoptotic Protease-Activating Factor 1 \| ∟ CRADD Signaling Adaptor Protein \| ∟ Receptor-Interacting Protein Serine-Threonine Kinase 2 Medical Subject Headings (MeSH) ∟ Amino Acids, Peptides, and Proteins ∟ Proteins ∟ Intracellular Signaling Peptides and Proteins ∟ Adaptor Proteins, Signal Transducing ∟ Nod Signaling Adaptor Proteins ∟ Nod2 Signaling Adaptor Protein 4 coordinate concepts ∟ Nod1 Signaling Adaptor Protein \| ∟ Apoptotic Protease-Activating Factor 1 \| ∟ CRADD Signaling Adaptor Protein \| ∟ Receptor-Interacting Protein Serine-Threonine Kinase 2 Medical Subject Headings (MeSH) ∟ Amino Acids, Peptides, and Proteins ∟ Proteins ∟ Intracellular Signaling Peptides and Proteins ∟ Apoptosis Regulatory Proteins ∟ CARD Signaling Adaptor Proteins ∟ Nod2 Signaling Adaptor Protein 4 coordinate concepts ∟ Nod1 Signaling Adaptor Protein \| ∟ Apoptotic Protease-Activating Factor 1 \| ∟ CRADD Signaling Adaptor Protein \| ∟ Receptor-Interacting Protein Serine-Threonine Kinase 2 X
Broader terms:	Medical Subject Headings (MeSH) ∟ Amino Acids, Peptides, and Proteins ∟ Peptides ∟ Intracellular Signaling Peptides and Proteins ∟ Adaptor Proteins, Signal Transducing ∟ CARD Signaling Adaptor Proteins ∟ Nod2 Signaling Adaptor Protein Medical Subject Headings (MeSH) ∟ Amino Acids, Peptides, and Proteins ∟ Peptides ∟ Intracellular Signaling Peptides and Proteins ∟ Adaptor Proteins, Signal Transducing ∟ Nod Signaling Adaptor Proteins ∟ Nod2 Signaling Adaptor Protein Medical Subject Headings (MeSH) ∟ Amino Acids, Peptides, and Proteins ∟ Peptides ∟ Intracellular Signaling Peptides and Proteins ∟ Apoptosis Regulatory Proteins ∟ CARD Signaling Adaptor Proteins ∟ Nod2 Signaling Adaptor Protein Medical Subject Headings (MeSH) ∟ Amino Acids, Peptides, and Proteins ∟ Proteins ∟ Carrier Proteins ∟ Adaptor Proteins, Signal Transducing ∟ CARD Signaling Adaptor Proteins ∟ Nod2 Signaling Adaptor Protein Medical Subject Headings (MeSH) ∟ Amino Acids, Peptides, and Proteins ∟ Proteins ∟ Carrier Proteins ∟ Adaptor Proteins, Signal Transducing ∟ Nod Signaling Adaptor Proteins ∟ Nod2 Signaling Adaptor Protein Medical Subject Headings (MeSH) ∟ Amino Acids, Peptides, and Proteins ∟ Proteins ∟ Intracellular Signaling Peptides and Proteins ∟ Adaptor Proteins, Signal Transducing ∟ CARD Signaling Adaptor Proteins ∟ Nod2 Signaling Adaptor Protein Medical Subject Headings (MeSH) ∟ Amino Acids, Peptides, and Proteins ∟ Proteins ∟ Intracellular Signaling Peptides and Proteins ∟ Adaptor Proteins, Signal Transducing ∟ Nod Signaling Adaptor Proteins ∟ Nod2 Signaling Adaptor Protein Medical Subject Headings (MeSH) ∟ Amino Acids, Peptides, and Proteins ∟ Proteins ∟ Intracellular Signaling Peptides and Proteins ∟ Apoptosis Regulatory Proteins ∟ CARD Signaling Adaptor Proteins ∟ Nod2 Signaling Adaptor Protein CARD Signaling Adaptor Proteins > Adaptor Proteins, Signal Transducing > Intracellular Signaling Peptides and Proteins > Peptides > Amino Acids, Peptides, and Proteins > Medical Subject Headings (MeSH) Nod Signaling Adaptor Proteins > Adaptor Proteins, Signal Transducing > Intracellular Signaling Peptides and Proteins > Peptides > Amino Acids, Peptides, and Proteins > Medical Subject Headings (MeSH) CARD Signaling Adaptor Proteins > Apoptosis Regulatory Proteins > Intracellular Signaling Peptides and Proteins > Peptides > Amino Acids, Peptides, and Proteins > Medical Subject Headings (MeSH) CARD Signaling Adaptor Proteins > Adaptor Proteins, Signal Transducing > Carrier Proteins > Proteins > Amino Acids, Peptides, and Proteins > Medical Subject Headings (MeSH) Nod Signaling Adaptor Proteins > Adaptor Proteins, Signal Transducing > Carrier Proteins > Proteins > Amino Acids, Peptides, and Proteins > Medical Subject Headings (MeSH) CARD Signaling Adaptor Proteins > Adaptor Proteins, Signal Transducing > Intracellular Signaling Peptides and Proteins > Proteins > Amino Acids, Peptides, and Proteins > Medical Subject Headings (MeSH) Nod Signaling Adaptor Proteins > Adaptor Proteins, Signal Transducing > Intracellular Signaling Peptides and Proteins > Proteins > Amino Acids, Peptides, and Proteins > Medical Subject Headings (MeSH) CARD Signaling Adaptor Proteins > Apoptosis Regulatory Proteins > Intracellular Signaling Peptides and Proteins > Proteins > Amino Acids, Peptides, and Proteins > Medical Subject Headings (MeSH) X
History note:	Carrier Proteins (2001-2004) \| Intracellular Signaling Peptides and Proteins (2005-2006)X
historyNote*:	2007 X
publicMeSHNote*:	2007 X
Scope note:	A NOD signaling adaptor protein that contains two C-terminal leucine-rich domains which recognize bacterial PEPTIDOGLYCAN. It signals via an N-terminal capase recruitment domain that interacts with other CARD SIGNALING ADAPTOR PROTEINS such as RIP SERINE-THEONINE KINASES. The protein plays a role in the host defense response by signaling the activation of CASPASES and the MAP KINASE SIGNALING SYSTEM. Mutations of the gene encoding the nucleotide oligomerization domain 2 protein have been associated with increased susceptibility to CROHN DISEASE. X
activeMeSHYear*:	2007X
dateCreated*:	2006-07-05X
dateEstablished*:	2007-01-01X
recordAuthorizer*:	sjnX
recordMaintainer*:	jmpX
recordOriginator*:	jmpX
Type:	Concept X
Coordinate terms:	Nod1 Signaling Adaptor Protein \| Apoptotic Protease-Activating Factor 1 \| CRADD Signaling Adaptor Protein \| Receptor-Interacting Protein Serine-Threonine Kinase 2 X
URI:	X
Labels and equivalent concepts:	Nucleotide Oligomerization Domain 2 Protein (en, replaced) Caspase Recruitment Domain Protein 15 (en, replaced) CARD15 Protein (en, replaced) X
Share:	X