ONKI3 | Medical Subject Headings

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The way property values are displayed: value/row values side by side

The way concept relations are shown: separately in hierarchy

Caspases, Initiator

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Hierarchy:	Medical Subject Headings (MeSH) ∟ Amino Acids, Peptides, and Proteins ∟ Peptides ∟ Intracellular Signaling Peptides and Proteins ∟ Apoptosis Regulatory Proteins ∟ Caspases ∟ Caspases, Initiator 1 coordinate concept 6 subordinate concepts ∟ Caspase 1 \| ∟ Caspase 10 \| ∟ Caspase 12 \| ∟ Caspase 2 \| ∟ Caspase 8 \| ∟ Caspase 9 ∟ Caspases, Effector Medical Subject Headings (MeSH) ∟ Amino Acids, Peptides, and Proteins ∟ Proteins ∟ Intracellular Signaling Peptides and Proteins ∟ Apoptosis Regulatory Proteins ∟ Caspases ∟ Caspases, Initiator 1 coordinate concept 6 subordinate concepts ∟ Caspase 1 \| ∟ Caspase 10 \| ∟ Caspase 12 \| ∟ Caspase 2 \| ∟ Caspase 8 \| ∟ Caspase 9 ∟ Caspases, Effector Medical Subject Headings (MeSH) ∟ Enzymes and Coenzymes ∟ Enzymes ∟ Hydrolases ∟ Peptide Hydrolases ∟ Endopeptidases ∟ Cysteine Endopeptidases ∟ Caspases ∟ Caspases, Initiator 1 coordinate concept 6 subordinate concepts ∟ Caspase 1 \| ∟ Caspase 10 \| ∟ Caspase 12 \| ∟ Caspase 2 \| ∟ Caspase 8 \| ∟ Caspase 9 ∟ Caspases, Effector X
Broader terms:	Medical Subject Headings (MeSH) ∟ Amino Acids, Peptides, and Proteins ∟ Peptides ∟ Intracellular Signaling Peptides and Proteins ∟ Apoptosis Regulatory Proteins ∟ Caspases ∟ Caspases, Initiator Medical Subject Headings (MeSH) ∟ Amino Acids, Peptides, and Proteins ∟ Proteins ∟ Intracellular Signaling Peptides and Proteins ∟ Apoptosis Regulatory Proteins ∟ Caspases ∟ Caspases, Initiator Medical Subject Headings (MeSH) ∟ Enzymes and Coenzymes ∟ Enzymes ∟ Hydrolases ∟ Peptide Hydrolases ∟ Endopeptidases ∟ Cysteine Endopeptidases ∟ Caspases ∟ Caspases, Initiator Caspases > Apoptosis Regulatory Proteins > Intracellular Signaling Peptides and Proteins > Peptides > Amino Acids, Peptides, and Proteins > Medical Subject Headings (MeSH) Caspases > Apoptosis Regulatory Proteins > Intracellular Signaling Peptides and Proteins > Proteins > Amino Acids, Peptides, and Proteins > Medical Subject Headings (MeSH) Caspases > Cysteine Endopeptidases > Endopeptidases > Peptide Hydrolases > Hydrolases > Enzymes > Enzymes and Coenzymes > Medical Subject Headings (MeSH) X
Narrower terms:	Caspase 1 \| Caspase 10 \| Caspase 12 \| Caspase 2 \| Caspase 8 \| Caspase 9 X
History note:	Caspases (1999-2006) \| Cysteine Proteinases (1997-1998)X
historyNote*:	2007 X
publicMeSHNote*:	2007 X
Scope note:	A subtype of caspases that contain long pro-domain regions that regulate the activation of the enzyme. The pro-domain regions contain protein-protein interaction motifs that can interact with specific signaling adaptor proteins such as DEATH DOMAIN RECEPTORS; DED SIGNALING ADAPTOR PROTEINS; and CARD SIGNALING ADAPTOR PROTEINS. Once activated, the initiator caspases can activate other caspases such as the EFFECTOR CASPASES. X
activeMeSHYear*:	2007X
dateCreated*:	2006-07-05X
dateEstablished*:	2007-01-01X
recordAuthorizer*:	sjnX
recordMaintainer*:	jmpX
recordOriginator*:	jmpX
Type:	Concept X
Coordinate terms:	Caspases, Effector X
URI:	X
Labels and equivalent concepts:	Initiaattorikaspaasit (fi) Initiator Caspases (en, replaced) X
Share:	X