ONKI3 | Medical Subject Headings

The ONKI is provided as a part of the ONKI Living Lab - an open lab for testing the latest semantic web technologies in practice, with real users like you. Currently, over 10 000 people are using ONKI each month.

We hope you like the ONKI service and enjoy using it for your purposes!

If you encounter any problems or have improvement ideas, please contact the ONKI team. We are also very much interested in your success stories in using ONKI - please share your experiences!

The ONKI Team

Jouni Tuominen, Living Lab contact person, APIs, widgets, publishing of ontologies, etc.
Eero Hyvönen, professor, head of research group

Former members: Kim Viljanen, Rami Alatalo.

Building the future of the Semantic Web and beyond.

SeCo's homepage
For the latest semantic news, follow us on Twitter and fan us on Facebook!

How can we help you?

Live presentations about ONKI: what it is? how to use it?
Support for creating and publishing ontologies.
Online technical support for using ONKI.
Co-operation in projects.
And more, please ask.


Hierarchy:	Medical Subject Headings (MeSH) ∟ Amino Acids, Peptides, and Proteins ∟ Peptides ∟ Intracellular Signaling Peptides and Proteins ∟ Apoptosis Regulatory Proteins ∟ Caspases ∟ Caspases, Initiator ∟ Caspase 8 5 coordinate concepts ∟ Caspase 1 \| ∟ Caspase 10 \| ∟ Caspase 12 \| ∟ Caspase 2 \| ∟ Caspase 9 Medical Subject Headings (MeSH) ∟ Amino Acids, Peptides, and Proteins ∟ Proteins ∟ Intracellular Signaling Peptides and Proteins ∟ Apoptosis Regulatory Proteins ∟ Caspases ∟ Caspases, Initiator ∟ Caspase 8 5 coordinate concepts ∟ Caspase 1 \| ∟ Caspase 10 \| ∟ Caspase 12 \| ∟ Caspase 2 \| ∟ Caspase 9 Medical Subject Headings (MeSH) ∟ Enzymes and Coenzymes ∟ Enzymes ∟ Hydrolases ∟ Peptide Hydrolases ∟ Endopeptidases ∟ Cysteine Endopeptidases ∟ Caspases ∟ Caspases, Initiator ∟ Caspase 8 5 coordinate concepts ∟ Caspase 1 \| ∟ Caspase 10 \| ∟ Caspase 12 \| ∟ Caspase 2 \| ∟ Caspase 9 X
Broader terms:	Medical Subject Headings (MeSH) ∟ Amino Acids, Peptides, and Proteins ∟ Peptides ∟ Intracellular Signaling Peptides and Proteins ∟ Apoptosis Regulatory Proteins ∟ Caspases ∟ Caspases, Initiator ∟ Caspase 8 Medical Subject Headings (MeSH) ∟ Amino Acids, Peptides, and Proteins ∟ Proteins ∟ Intracellular Signaling Peptides and Proteins ∟ Apoptosis Regulatory Proteins ∟ Caspases ∟ Caspases, Initiator ∟ Caspase 8 Medical Subject Headings (MeSH) ∟ Enzymes and Coenzymes ∟ Enzymes ∟ Hydrolases ∟ Peptide Hydrolases ∟ Endopeptidases ∟ Cysteine Endopeptidases ∟ Caspases ∟ Caspases, Initiator ∟ Caspase 8 Caspases, Initiator > Caspases > Apoptosis Regulatory Proteins > Intracellular Signaling Peptides and Proteins > Peptides > Amino Acids, Peptides, and Proteins > Medical Subject Headings (MeSH) Caspases, Initiator > Caspases > Apoptosis Regulatory Proteins > Intracellular Signaling Peptides and Proteins > Proteins > Amino Acids, Peptides, and Proteins > Medical Subject Headings (MeSH) Caspases, Initiator > Caspases > Cysteine Endopeptidases > Endopeptidases > Peptide Hydrolases > Hydrolases > Enzymes > Enzymes and Coenzymes > Medical Subject Headings (MeSH) X
historyNote*:	2007(2000) X
publicMeSHNote*:	2007; CASPASE 8 was indexed under CASPASES 1999-2006 & under CYSTEINE PROTEINASES 1997-1998 X
Scope note:	A long pro-domain caspase that contains a death effector domain in its pro-domain region. Caspase 8 plays a role in APOPTOSIS by cleaving and activating EFFECTOR CASPASES. Activation of this enzyme can occur via the interaction of its N-terminal death effector domain with DEATH DOMAIN RECEPTOR SIGNALING ADAPTOR PROTEINS. X
activeMeSHYear*:	2007X
dateCreated*:	2006-07-05X
dateEstablished*:	2007-01-01X
recordAuthorizer*:	sjnX
recordMaintainer*:	jmpX
recordOriginator*:	jmpX
Type:	Concept X
Coordinate terms:	Caspase 1 \| Caspase 10 \| Caspase 12 \| Caspase 2 \| Caspase 9 X
URI:	X
Labels and equivalent concepts:	Kaspaasi 8 (fi) Mch5 Protease (en, replaced) Pro-Caspase-8 (en, replaced) MACH Protein (en, replaced) FLICE Protein (en, replaced) Caspase-8 (en, replaced) CAP4 Protease (en, replaced) X
Share:	X