ONKI3 | Medical Subject Headings

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Hierarchy:	Medical Subject Headings (MeSH) ∟ Amino Acids, Peptides, and Proteins ∟ Peptides ∟ Intracellular Signaling Peptides and Proteins ∟ Apoptosis Regulatory Proteins ∟ Caspases ∟ Caspases, Initiator ∟ Caspase 2 5 coordinate concepts ∟ Caspase 1 \| ∟ Caspase 10 \| ∟ Caspase 12 \| ∟ Caspase 8 \| ∟ Caspase 9 Medical Subject Headings (MeSH) ∟ Amino Acids, Peptides, and Proteins ∟ Proteins ∟ Intracellular Signaling Peptides and Proteins ∟ Apoptosis Regulatory Proteins ∟ Caspases ∟ Caspases, Initiator ∟ Caspase 2 5 coordinate concepts ∟ Caspase 1 \| ∟ Caspase 10 \| ∟ Caspase 12 \| ∟ Caspase 8 \| ∟ Caspase 9 Medical Subject Headings (MeSH) ∟ Enzymes and Coenzymes ∟ Enzymes ∟ Hydrolases ∟ Peptide Hydrolases ∟ Endopeptidases ∟ Cysteine Endopeptidases ∟ Caspases ∟ Caspases, Initiator ∟ Caspase 2 5 coordinate concepts ∟ Caspase 1 \| ∟ Caspase 10 \| ∟ Caspase 12 \| ∟ Caspase 8 \| ∟ Caspase 9 X
Broader terms:	Medical Subject Headings (MeSH) ∟ Amino Acids, Peptides, and Proteins ∟ Peptides ∟ Intracellular Signaling Peptides and Proteins ∟ Apoptosis Regulatory Proteins ∟ Caspases ∟ Caspases, Initiator ∟ Caspase 2 Medical Subject Headings (MeSH) ∟ Amino Acids, Peptides, and Proteins ∟ Proteins ∟ Intracellular Signaling Peptides and Proteins ∟ Apoptosis Regulatory Proteins ∟ Caspases ∟ Caspases, Initiator ∟ Caspase 2 Medical Subject Headings (MeSH) ∟ Enzymes and Coenzymes ∟ Enzymes ∟ Hydrolases ∟ Peptide Hydrolases ∟ Endopeptidases ∟ Cysteine Endopeptidases ∟ Caspases ∟ Caspases, Initiator ∟ Caspase 2 Caspases, Initiator > Caspases > Apoptosis Regulatory Proteins > Intracellular Signaling Peptides and Proteins > Peptides > Amino Acids, Peptides, and Proteins > Medical Subject Headings (MeSH) Caspases, Initiator > Caspases > Apoptosis Regulatory Proteins > Intracellular Signaling Peptides and Proteins > Proteins > Amino Acids, Peptides, and Proteins > Medical Subject Headings (MeSH) Caspases, Initiator > Caspases > Cysteine Endopeptidases > Endopeptidases > Peptide Hydrolases > Hydrolases > Enzymes > Enzymes and Coenzymes > Medical Subject Headings (MeSH) X
historyNote*:	2007(1994) X
publicMeSHNote*:	2007; CASPASE 2 was indexed under CASPASES 1994-2006 X
Scope note:	A long pro-domain caspase that contains a caspase recruitment domain in its pro-domain region. Activation of this enzyme can occur via the interaction of its caspase recruitment domain with CARD SIGNALING ADAPTOR PROTEINS. Caspase 2 plays a role in APOPTOSIS by cleaving and activating effector pro-caspases. Several isoforms of this protein exist due to multiple alternative splicing of its MESSENGER RNA. X
activeMeSHYear*:	2007X
dateCreated*:	2006-07-05X
dateEstablished*:	2007-01-01X
recordAuthorizer*:	sjnX
recordMaintainer*:	jmpX
recordOriginator*:	jmpX
Type:	Concept X
Coordinate terms:	Caspase 1 \| Caspase 10 \| Caspase 12 \| Caspase 8 \| Caspase 9 X
URI:	X
Labels and equivalent concepts:	Kaspaasi 2 (fi) Pro-Caspase-2 (en, replaced) ICH-1 Protease (en, replaced) Caspase-2 (en, replaced) X
Share:	X