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Wnt Proteins
Hierarchy: | ∟ ∟ ∟ ∟ Wnt Proteins 18 coordinate concepts2 subordinate concepts∟ ∟ ∟ ∟ Wnt Proteins 18 coordinate concepts2 subordinate concepts∟ ∟ ∟ Wnt Proteins 18 coordinate concepts2 subordinate conceptsX |
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historyNote*: | 2006(1987)
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publicMeSHNote*: | 2006; WNT PROTEINS was indexed under INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS 2005, & under PROTO-ONCOGENE PROTEINS 1987-2005
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Scope note: | Wnt proteins are a large family of secreted glycoproteins that play essential roles in EMBRYONIC AND FETAL DEVELOPMENT, and tissue maintenance. They bind to FRIZZLED RECEPTORS and act as PARACRINE PROTEIN FACTORS to initiate a variety of SIGNAL TRANSDUCTION PATHWAYS. The canonical Wnt signaling pathway stabilizes the transcriptional coactivator BETA CATENIN.
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activeMeSHYear*: | 2007X |
dateCreated*: | 2005-06-30X |
dateEstablished*: | 2006-01-01X |
dateRevised*: | 2006-07-05X |
recordAuthorizer*: | sjnX |
recordMaintainer*: | jmpX |
recordOriginator*: | DRCX |
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Labels and equivalent concepts: | Wnt-proteiinit (fi) XWnt Factors (en, replaced) Wingless Type Proteins (en, replaced) |
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