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The way concept relations are shown:
Vascular Endothelial Growth Factor A
Hierarchy: | ∟ ∟ ∟ ∟ ∟ ∟ Vascular Endothelial Growth Factor A 4 coordinate concepts∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ Vascular Endothelial Growth Factor A 4 coordinate concepts∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ Vascular Endothelial Growth Factor A 4 coordinate concepts∟ ∟ ∟ ∟ |
Broader terms: | |
History note: | Endothelial Growth Factors (2000-2003)X |
historyNote*: | 2004; use VASCULAR ENDOTHELIAL GROWTH FACTOR A (NM) 2000-2002
X |
publicMeSHNote*: | 2004; VASCULAR ENDOTHELIAL GROWTH FACTOR was indexed under ENDOTHELIAL GROWTH FACTORS 2000-2002
X |
Scope note: | The original member of the family of endothelial cell growth factors referred to as VASCULAR ENDOTHELIAL GROWTH FACTORS. Vascular endothelial growth factor-A was originally isolated from tumor cells and referred to as "tumor angiogenesis factor" and "vascular permeability factor". Although expressed at high levels in certain tumor-derived cells it is produced by a wide variety of cell types. In addition to stimulating vascular growth and vascular permeability it may play a role in stimulating VASODILATION via NITRIC OXIDE-dependent pathways. Alternative splicing of the mRNA for vascular endothelial growth factor A results in several isoforms of the protein being produced.
X |
activeMeSHYear*: | 2007X |
dateCreated*: | 2003-07-09X |
dateEstablished*: | 2004-01-01X |
dateRevised*: | 2006-07-05X |
recordAuthorizer*: | sjnX |
recordMaintainer*: | jmpX |
recordOriginator*: | jmpX |
Type: | |
Coordinate terms: | |
URI: | |
Labels and equivalent concepts: | Verisuonten endoteelikasvutekijä A (fi) XVEGF-A (fi, replaced) Vaskulär endotelcellstillväxtfaktor A (sv) VEGF (en, replaced) VEGF-A (en, replaced) Vasculotropin (en, replaced) Vascular Permeability Factor (en, replaced) Vascular Endothelial Growth Factor (en, replaced) Vascular Endothelial Growth Factor-A (en, replaced) GD-VEGF (en, replaced) |
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