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The way concept relations are shown:
The way concept relations are shown:
Integrin alphaVbeta3
Hierarchy: | ∟ ∟ ∟ ∟ ∟ ∟ Integrin alphaVbeta3 9 coordinate concepts∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ Integrin alphaVbeta3 9 coordinate concepts∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ Integrin alphaVbeta3 9 coordinate concepts∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ Integrin alphaVbeta3 9 coordinate concepts∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ Integrin alphaVbeta3 9 coordinate concepts∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ Integrin alphaVbeta3 9 coordinate concepts∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ |
Broader terms: | |
Annotation: | do not confuse X ref VITRONECTIN RECEPTOR with VITRONECTIN RECEPTORS
X |
historyNote*: | 2003; use RECEPTORS, VITRONECTIN 1996-2002
X |
publicMeSHNote*: | 2003; see RECEPTORS, VITRONECTIN 1996-2002
X |
Scope note: | An integrin that binds to a variety of plasma and extracellular matrix proteins containing the conserved RGD amino acid sequence and modulates cell adhesion. Integrin alphavbeta3 is highly expressed in OSTEOCLASTS where it may play role in BONE RESORPTION. It is also abundant in vascular smooth muscle and endothelial cells, and in some tumor cells, where it is involved in angiogenesis and cell migration. Although often referred to as the vitronectin receptor there is more than one receptor for vitronectin (RECEPTORS, VITRONECTIN).
X |
activeMeSHYear*: | |
dateCreated*: | 2002-07-02X |
dateEstablished*: | 2003-01-01X |
dateRevised*: | 2003-07-09X |
recordAuthorizer*: | sjnX |
recordMaintainer*: | jmpX |
recordOriginator*: | MDJX |
Type: | |
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URI: | |
Labels and equivalent concepts: | AlfaVbeeta3-integriini (fi) XAlfaVbeta3-integrin (sv) Vitronectin Receptor (en, replaced) Receptors, alpha-v beta-3 Integrin (en, replaced) Integrin alpha-v beta-3 (en, replaced) alpha-v beta-3 Integrin Receptors (en, replaced) |
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