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The way concept relations are shown:
Integrin alpha1beta1
Hierarchy: | ∟ ∟ ∟ ∟ ∟ ∟ Integrin alpha1beta1 6 coordinate concepts∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ Integrin alpha1beta1 6 coordinate concepts∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ Integrin alpha1beta1 6 coordinate concepts∟ ∟ ∟ ∟ ∟ ∟ |
Broader terms: | |
History note: | Integrins (1994-2002)X |
historyNote*: | 2003; use INTEGRIN ALPHA1BETA1 (NM) 1994-2002
X |
publicMeSHNote*: | 2003; INTEGRIN ALPHA1BETA1 was indexed under INTEGRINS 1994-2002
X |
Scope note: | Integrin alpha1beta1 functions as a receptor for LAMININ and COLLAGEN. It is widely expressed during development, but in the adult is the predominant laminin receptor (RECEPTORS, LAMININ) in mature SMOOTH MUSCLE CELLS, where it is important for maintenance of the differentiated phenotype of these cells. Integrin alpha1beta1 is also found in LYMPHOCYTES and microvascular endothelial cells, and may play a role in angiogenesis. In SCHWANN CELLS and neural crest cells, it is involved in cell migration. Integrin alpha1beta1 is also known as VLA-1 and CD49a-CD29.
X |
activeMeSHYear*: | |
dateCreated*: | 2002-07-02X |
dateEstablished*: | 2003-01-01X |
dateRevised*: | 2005-06-30X |
recordAuthorizer*: | sjnX |
recordMaintainer*: | jmpX |
recordOriginator*: | MDJX |
Type: | |
Coordinate terms: | |
URI: | |
Labels and equivalent concepts: | Alfa1beeta1-integriini (fi) XAlpha1beta1-integrin (sv) VLA-1 (en, replaced) Integrin alpha(1)beta(1) (en, replaced) CD49a-CD29 (en, replaced) alpha1beta1 Integrin (en, replaced) |
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