ONKI3 | Medical Subject Headings

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The way property values are displayed: value/row values side by side

The way concept relations are shown: separately in hierarchy

Integrin alpha6beta1

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Hierarchy:	Medical Subject Headings (MeSH) ∟ Amino Acids, Peptides, and Proteins ∟ Proteins ∟ Glycoproteins ∟ Membrane Glycoproteins ∟ Platelet Membrane Glycoproteins ∟ Integrin alpha6beta1 13 coordinate concepts ∟ Integrin alpha1beta1 \| ∟ Integrin alpha2beta1 \| ∟ Integrin alpha3beta1 \| ∟ Integrin alpha5beta1 \| ∟ Integrin alpha6beta4 \| ∟ Integrin alpha4beta1 \| ∟ Antigens, CD36 \| ∟ Integrin alphaVbeta3 \| ∟ Lysosomal-Associated Membrane Protein 1 \| ∟ P-Selectin \| ∟ Platelet Glycoprotein GPIb-IX Complex \| ∟ Platelet Glycoprotein GPIIb-IIIa Complex \| ∟ Receptors, Thrombin Medical Subject Headings (MeSH) ∟ Amino Acids, Peptides, and Proteins ∟ Proteins ∟ Membrane Proteins ∟ Membrane Glycoproteins ∟ Platelet Membrane Glycoproteins ∟ Integrin alpha6beta1 13 coordinate concepts ∟ Integrin alpha1beta1 \| ∟ Integrin alpha2beta1 \| ∟ Integrin alpha3beta1 \| ∟ Integrin alpha5beta1 \| ∟ Integrin alpha6beta4 \| ∟ Integrin alpha4beta1 \| ∟ Antigens, CD36 \| ∟ Integrin alphaVbeta3 \| ∟ Lysosomal-Associated Membrane Protein 1 \| ∟ P-Selectin \| ∟ Platelet Glycoprotein GPIb-IX Complex \| ∟ Platelet Glycoprotein GPIIb-IIIa Complex \| ∟ Receptors, Thrombin Medical Subject Headings (MeSH) ∟ Amino Acids, Peptides, and Proteins ∟ Proteins ∟ Membrane Proteins ∟ Receptors, Cell Surface ∟ Receptors, Immunologic ∟ Integrins ∟ Receptors, Very Late Antigen ∟ Integrin alpha6beta1 13 coordinate concepts ∟ Integrin alpha1beta1 \| ∟ Integrin alpha2beta1 \| ∟ Integrin alpha3beta1 \| ∟ Integrin alpha5beta1 \| ∟ Integrin alpha6beta4 \| ∟ Integrin alpha4beta1 \| ∟ Antigens, CD36 \| ∟ Integrin alphaVbeta3 \| ∟ Lysosomal-Associated Membrane Protein 1 \| ∟ P-Selectin \| ∟ Platelet Glycoprotein GPIb-IX Complex \| ∟ Platelet Glycoprotein GPIIb-IIIa Complex \| ∟ Receptors, Thrombin Medical Subject Headings (MeSH) ∟ Amino Acids, Peptides, and Proteins ∟ Proteins ∟ Membrane Proteins ∟ Receptors, Cell Surface ∟ Receptors, Immunologic ∟ Platelet Membrane Glycoproteins ∟ Integrin alpha6beta1 13 coordinate concepts ∟ Integrin alpha1beta1 \| ∟ Integrin alpha2beta1 \| ∟ Integrin alpha3beta1 \| ∟ Integrin alpha5beta1 \| ∟ Integrin alpha6beta4 \| ∟ Integrin alpha4beta1 \| ∟ Antigens, CD36 \| ∟ Integrin alphaVbeta3 \| ∟ Lysosomal-Associated Membrane Protein 1 \| ∟ P-Selectin \| ∟ Platelet Glycoprotein GPIb-IX Complex \| ∟ Platelet Glycoprotein GPIIb-IIIa Complex \| ∟ Receptors, Thrombin Medical Subject Headings (MeSH) ∟ Amino Acids, Peptides, and Proteins ∟ Proteins ∟ Membrane Proteins ∟ Receptors, Cell Surface ∟ Receptors, Immunologic ∟ Receptors, Laminin ∟ Integrin alpha6beta1 13 coordinate concepts ∟ Integrin alpha1beta1 \| ∟ Integrin alpha2beta1 \| ∟ Integrin alpha3beta1 \| ∟ Integrin alpha5beta1 \| ∟ Integrin alpha6beta4 \| ∟ Integrin alpha4beta1 \| ∟ Antigens, CD36 \| ∟ Integrin alphaVbeta3 \| ∟ Lysosomal-Associated Membrane Protein 1 \| ∟ P-Selectin \| ∟ Platelet Glycoprotein GPIb-IX Complex \| ∟ Platelet Glycoprotein GPIIb-IIIa Complex \| ∟ Receptors, Thrombin Medical Subject Headings (MeSH) ∟ Carbohydrates ∟ Glycoconjugates ∟ Glycoproteins ∟ Membrane Glycoproteins ∟ Platelet Membrane Glycoproteins ∟ Integrin alpha6beta1 13 coordinate concepts ∟ Integrin alpha1beta1 \| ∟ Integrin alpha2beta1 \| ∟ Integrin alpha3beta1 \| ∟ Integrin alpha5beta1 \| ∟ Integrin alpha6beta4 \| ∟ Integrin alpha4beta1 \| ∟ Antigens, CD36 \| ∟ Integrin alphaVbeta3 \| ∟ Lysosomal-Associated Membrane Protein 1 \| ∟ P-Selectin \| ∟ Platelet Glycoprotein GPIb-IX Complex \| ∟ Platelet Glycoprotein GPIIb-IIIa Complex \| ∟ Receptors, Thrombin X
Broader terms:	Medical Subject Headings (MeSH) ∟ Amino Acids, Peptides, and Proteins ∟ Proteins ∟ Glycoproteins ∟ Membrane Glycoproteins ∟ Platelet Membrane Glycoproteins ∟ Integrin alpha6beta1 Medical Subject Headings (MeSH) ∟ Amino Acids, Peptides, and Proteins ∟ Proteins ∟ Membrane Proteins ∟ Membrane Glycoproteins ∟ Platelet Membrane Glycoproteins ∟ Integrin alpha6beta1 Medical Subject Headings (MeSH) ∟ Amino Acids, Peptides, and Proteins ∟ Proteins ∟ Membrane Proteins ∟ Receptors, Cell Surface ∟ Receptors, Immunologic ∟ Integrins ∟ Receptors, Very Late Antigen ∟ Integrin alpha6beta1 Medical Subject Headings (MeSH) ∟ Amino Acids, Peptides, and Proteins ∟ Proteins ∟ Membrane Proteins ∟ Receptors, Cell Surface ∟ Receptors, Immunologic ∟ Platelet Membrane Glycoproteins ∟ Integrin alpha6beta1 Medical Subject Headings (MeSH) ∟ Amino Acids, Peptides, and Proteins ∟ Proteins ∟ Membrane Proteins ∟ Receptors, Cell Surface ∟ Receptors, Immunologic ∟ Receptors, Laminin ∟ Integrin alpha6beta1 Medical Subject Headings (MeSH) ∟ Carbohydrates ∟ Glycoconjugates ∟ Glycoproteins ∟ Membrane Glycoproteins ∟ Platelet Membrane Glycoproteins ∟ Integrin alpha6beta1 Platelet Membrane Glycoproteins > Membrane Glycoproteins > Glycoproteins > Proteins > Amino Acids, Peptides, and Proteins > Medical Subject Headings (MeSH) Platelet Membrane Glycoproteins > Membrane Glycoproteins > Membrane Proteins > Proteins > Amino Acids, Peptides, and Proteins > Medical Subject Headings (MeSH) Receptors, Very Late Antigen > Integrins > Receptors, Immunologic > Receptors, Cell Surface > Membrane Proteins > Proteins > Amino Acids, Peptides, and Proteins > Medical Subject Headings (MeSH) Platelet Membrane Glycoproteins > Receptors, Immunologic > Receptors, Cell Surface > Membrane Proteins > Proteins > Amino Acids, Peptides, and Proteins > Medical Subject Headings (MeSH) Receptors, Laminin > Receptors, Immunologic > Receptors, Cell Surface > Membrane Proteins > Proteins > Amino Acids, Peptides, and Proteins > Medical Subject Headings (MeSH) Platelet Membrane Glycoproteins > Membrane Glycoproteins > Glycoproteins > Glycoconjugates > Carbohydrates > Medical Subject Headings (MeSH) X
History note:	Integrins (1992-2002)X
historyNote*:	2003; use INTEGRIN ALPHA6BETA1 (NM) 1992-2002 X
publicMeSHNote*:	2003; INTEGRIN ALPHA5BETA1 was indexed under INTEGRINS 1992-2002 X
Scope note:	A cell surface receptor mediating cell adhesion to the EXTRACELLULAR MATRIX and to other cells via binding to LAMININ. It is involved in cell migration, embryonic development, leukocyte activation and tumor cell invasiveness. Integrin alpha6beta1 is the major laminin receptor on PLATELETS; LEUKOCYTES; and many EPITHELIAL CELLS, and ligand binding may activate a number of signal transduction pathways. Alternative splicing of the cytoplasmic domain of the alpha6 subunit (INTEGRIN ALPHA6) results in the formation of A and B isoforms of the heterodimer, which are expressed in a tissue-specific manner. X
activeMeSHYear*:	2004 \| 2005 \| 2006 \| 2006A \| 2007X
dateCreated*:	2002-07-02X
dateEstablished*:	2003-01-01X
dateRevised*:	2005-07-27X
recordAuthorizer*:	agsX
recordMaintainer*:	agsX
recordOriginator*:	MDJX
Type:	Concept X
Coordinate terms:	Integrin alpha1beta1 \| Integrin alpha2beta1 \| Integrin alpha3beta1 \| Integrin alpha5beta1 \| Integrin alpha6beta4 \| Integrin alpha4beta1 \| Antigens, CD36 \| Integrin alphaVbeta3 \| Lysosomal-Associated Membrane Protein 1 \| P-Selectin \| Platelet Glycoprotein GPIb-IX Complex \| Platelet Glycoprotein GPIIb-IIIa Complex \| Receptors, Thrombin X
URI:	X
Labels and equivalent concepts:	Alfa6beeta1-integriini (fi) Alfa6beta1-integrin (sv) Platelet Glycoprotein I'c-IIa (en, replaced) VLA-6 (en, replaced) Integrin alpha(6)beta(1) (en, replaced) CD49f-CD29 (en, replaced) alpha6beta1 Integrin (en, replaced) alpha 6 beta 1 Integrin (en, replaced) X
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