ONKI3 | Medical Subject Headings

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The way property values are displayed: value/row values side by side

The way concept relations are shown: separately in hierarchy

alpha Karyopherins

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Hierarchy:	Medical Subject Headings (MeSH) ∟ Amino Acids, Peptides, and Proteins ∟ Proteins ∟ Carrier Proteins ∟ Membrane Transport Proteins ∟ Nucleocytoplasmic Transport Proteins ∟ Karyopherins ∟ alpha Karyopherins 1 coordinate concept ∟ beta Karyopherins Medical Subject Headings (MeSH) ∟ Amino Acids, Peptides, and Proteins ∟ Proteins ∟ Membrane Proteins ∟ Membrane Transport Proteins ∟ Nucleocytoplasmic Transport Proteins ∟ Karyopherins ∟ alpha Karyopherins 1 coordinate concept ∟ beta Karyopherins Medical Subject Headings (MeSH) ∟ Amino Acids, Peptides, and Proteins ∟ Proteins ∟ Nuclear Proteins ∟ Karyopherins ∟ alpha Karyopherins 1 coordinate concept ∟ beta Karyopherins X
Broader terms:	Medical Subject Headings (MeSH) ∟ Amino Acids, Peptides, and Proteins ∟ Proteins ∟ Carrier Proteins ∟ Membrane Transport Proteins ∟ Nucleocytoplasmic Transport Proteins ∟ Karyopherins ∟ alpha Karyopherins Medical Subject Headings (MeSH) ∟ Amino Acids, Peptides, and Proteins ∟ Proteins ∟ Membrane Proteins ∟ Membrane Transport Proteins ∟ Nucleocytoplasmic Transport Proteins ∟ Karyopherins ∟ alpha Karyopherins Medical Subject Headings (MeSH) ∟ Amino Acids, Peptides, and Proteins ∟ Proteins ∟ Nuclear Proteins ∟ Karyopherins ∟ alpha Karyopherins Karyopherins > Nucleocytoplasmic Transport Proteins > Membrane Transport Proteins > Carrier Proteins > Proteins > Amino Acids, Peptides, and Proteins > Medical Subject Headings (MeSH) Karyopherins > Nucleocytoplasmic Transport Proteins > Membrane Transport Proteins > Membrane Proteins > Proteins > Amino Acids, Peptides, and Proteins > Medical Subject Headings (MeSH) Karyopherins > Nuclear Proteins > Proteins > Amino Acids, Peptides, and Proteins > Medical Subject Headings (MeSH) X
History note:	Nuclear Proteins (1994-2001)X
historyNote*:	2002; use ALPHA KARYOPHERINS (NM) 1994-2001; for IMPORTIN-ALPHA use KARYOPHERINS 1995-2001; for NLS-BINDING PROTEIN, NLSBP & NUCLEAR LOCALIZATION SIGNAL-BINDING PROTEIN use NOPP140 (NM) 1992-2001 X
publicMeSHNote*:	2002; KARYOPHERIN ALPHA (now ALPHA KARYOPHERINS) was indexed under NUCLEAR PROTEINS 1994-2001; IMPORTIN-ALPHA was indexed under NUCLEAR PROTEINS 1995-2001; NLS-BINDING PROTEIN, NLSBP & NUCLEAR LOCALIZATION SIGNAL-BINDING PROTEIN were indexed under NUCLEAR PROTEINS & PHOSPHOPROTEINS 1992-2001 X
Scope note:	Nucleocytoplasmic transport molecules that bind to the NUCLEAR LOCALIZATION SIGNALS of cytoplasmic molecules destined to be imported into the CELL NUCLEUS. Once attached to their cargo they bind to BETA KARYOPHERINS and are transported through the NUCLEAR PORE COMPLEX. Inside the CELL NUCLEUS alpha karyopherins dissociate from beta karypherins and their cargo. They then form a complex with CELLULAR APOPTOSIS SUSCEPTIBILITY PROTEIN and RAN GTP-BINDING PROTEIN which is exported to the CYTOPLASM. X
activeMeSHYear*:	2006 \| 2006A \| 2007X
dateCreated*:	2001-07-25X
dateEstablished*:	2002-01-01X
dateRevised*:	2005-07-12X
recordAuthorizer*:	agsX
recordMaintainer*:	agsX
recordOriginator*:	jmpX
Related term:	Nuclear Localization Signals X
Type:	Concept X
Coordinate terms:	beta Karyopherins X
URI:	X
Labels and equivalent concepts:	Alfakaryoferiinit (fi) Alfa-karyoferiini (fi, replaced) Alfa-karyoferiinit (fi, replaced) Alfakaryoferiini (fi, replaced) alfakaryoferiner (sv) Nuclear Localization Signal-Binding Protein (en, replaced) Nuclear Localization Sequence Receptor (en, replaced) NLSBP (en, replaced) Karyopherin alpha (en, replaced) NLS Receptor (en, replaced) NLS-Binding Protein (en, replaced) Importin-alpha (en, replaced) X
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