ONKI3 | Medical Subject Headings

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Hierarchy:	Medical Subject Headings (MeSH) ∟ Genetic Phenomena ∟ Inheritance Patterns ∟ Genes, Recessive ∟ Genes, Tumor Suppressor ∟ Genes, BRCA2 10 coordinate concepts ∟ Genes, APC \| ∟ Genes, BRCA1 \| ∟ Genes, DCC \| ∟ Genes, MCC \| ∟ Genes, Neurofibromatosis 1 \| ∟ Genes, Neurofibromatosis 2 \| ∟ Genes, p16 \| ∟ Genes, p53 \| ∟ Genes, Retinoblastoma \| ∟ Genes, Wilms Tumor Medical Subject Headings (MeSH) ∟ Genetic Structures ∟ Genome ∟ Genome Components ∟ Genes ∟ Genes, Neoplasm ∟ Genes, Tumor Suppressor ∟ Genes, BRCA2 10 coordinate concepts ∟ Genes, APC \| ∟ Genes, BRCA1 \| ∟ Genes, DCC \| ∟ Genes, MCC \| ∟ Genes, Neurofibromatosis 1 \| ∟ Genes, Neurofibromatosis 2 \| ∟ Genes, p16 \| ∟ Genes, p53 \| ∟ Genes, Retinoblastoma \| ∟ Genes, Wilms Tumor Medical Subject Headings (MeSH) ∟ Genetic Structures ∟ Genome ∟ Genome Components ∟ Genes ∟ Genes, Recessive ∟ Genes, Tumor Suppressor ∟ Genes, BRCA2 10 coordinate concepts ∟ Genes, APC \| ∟ Genes, BRCA1 \| ∟ Genes, DCC \| ∟ Genes, MCC \| ∟ Genes, Neurofibromatosis 1 \| ∟ Genes, Neurofibromatosis 2 \| ∟ Genes, p16 \| ∟ Genes, p53 \| ∟ Genes, Retinoblastoma \| ∟ Genes, Wilms Tumor X
Broader terms:	Medical Subject Headings (MeSH) ∟ Genetic Phenomena ∟ Inheritance Patterns ∟ Genes, Recessive ∟ Genes, Tumor Suppressor ∟ Genes, BRCA2 Medical Subject Headings (MeSH) ∟ Genetic Structures ∟ Genome ∟ Genome Components ∟ Genes ∟ Genes, Neoplasm ∟ Genes, Tumor Suppressor ∟ Genes, BRCA2 Medical Subject Headings (MeSH) ∟ Genetic Structures ∟ Genome ∟ Genome Components ∟ Genes ∟ Genes, Recessive ∟ Genes, Tumor Suppressor ∟ Genes, BRCA2 Genes, Tumor Suppressor > Genes, Recessive > Inheritance Patterns > Genetic Phenomena > Medical Subject Headings (MeSH) Genes, Tumor Suppressor > Genes, Neoplasm > Genes > Genome Components > Genome > Genetic Structures > Medical Subject Headings (MeSH) Genes, Tumor Suppressor > Genes, Recessive > Genes > Genome Components > Genome > Genetic Structures > Medical Subject Headings (MeSH) X
Annotation:	BRCA stands for "BReast CAncer" X
History note:	Genes, Tumor Suppressor (1995-2001)X
historyNote*:	2002 X
publicMeSHNote*:	2002 X
Scope note:	A tumor suppressor gene (GENES, TUMOR SUPPRESSOR) located on human chromosome 13 at locus 13q12.3. Mutations in this gene predispose humans to breast and ovarian cancer. It encodes a large, nuclear protein that is an essential component of DNA repair pathways, suppressing the formation of gross chromosomal rearrangements. (from Genes Dev 2000;14(11):1400-6) X
activeMeSHYear*:	2006 \| 2006A \| 2007X
dateCreated*:	2001-07-25X
dateEstablished*:	2002-01-01X
dateRevised*:	2005-07-14X
recordAuthorizer*:	agsX
recordMaintainer*:	agsX
recordOriginator*:	nnsX
Related term:	BRCA2 Protein X
Type:	Concept X
Coordinate terms:	Genes, APC \| Genes, BRCA1 \| Genes, DCC \| Genes, MCC \| Genes, Neurofibromatosis 1 \| Genes, Neurofibromatosis 2 \| Genes, p16 \| Genes, p53 \| Genes, Retinoblastoma \| Genes, Wilms Tumor X
URI:	X
Labels and equivalent concepts:	BRCA2-geenit (fi) BRCA2-geeni (fi, replaced) BRCA2 (fi, replaced) BRCA2-gener (sv) Gener, BRCA2 (sv, replaced) BRCA2 Gene (en, replaced) X
Share:	X