The way property values are displayed:
The way concept relations are shown:
The way concept relations are shown:
Receptor, trkA
Hierarchy: | ∟ ∟ ∟ ∟ ∟ ∟ Receptor, trkA 23 coordinate concepts∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ Receptor, trkA 23 coordinate concepts∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ Receptor, trkA 23 coordinate concepts∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ ∟ |
Broader terms: | |
Annotation: | DF: RECEPT TRKA
X |
History note: | Proto-Oncogene Proteins (1990-1999) | Receptor Protein-Tyrosine Kinases (1994-1999) | Receptors, Nerve Growth Factor (1994-1999)X |
historyNote*: | 2000; use RECEPTOR, TYPE 1 NEUROTROPHIC TYROSINE KINASE(NM) 1990-1999
X |
publicMeSHNote*: | 2000; PROTO-ONCOGENE PROTEIN TRK (now RECEPTOR, TYPE 1 NEUROTROPHIC TYROSINE KINASE) was indexed under PROTO-ONCOGENE PROTEINS 1990-1999, RECEPTOR PROTEIN-TYROSINE KINASE 1994-1999 & RECEPTORS, NERVE GROWTH FACTOR 1994-1999
X |
Scope note: | A protein-tyrosine kinase receptor that is specific for NERVE GROWTH FACTOR; NEUROTROPHIN 3; neurotrophin 4, neurotrophin 5. It plays a crucial role in pain sensation and thermoregulation in humans. Gene mutations that cause loss of receptor function are associated with congenital insensitivity to pain with anhidrosis, while gene rearrangements that activate the protein-tyrosine kinase function are associated with tumorigenesis.
X |
activeMeSHYear*: | |
dateCreated*: | 1999-11-04X |
dateEstablished*: | 2000-01-01X |
dateRevised*: | 2005-06-30X |
recordAuthorizer*: | sjnX |
recordMaintainer*: | jmpX |
recordOriginator*: | jmpX |
Type: | |
Coordinate terms: | |
URI: | |
Labels and equivalent concepts: | TrkA-reseptori (fi) XNeurotrofisen tyrosiinikinaasi tyyppi 1:n reseptori (fi, replaced) Gp140(c-TRK) (fi, replaced) NTRK1-reseptori (fi, replaced) Proto-onkogeeniproteiini trk (fi, replaced) TrkA-reseptori (fi, replaced) Trk proto-onkogeeniproteiini (fi, replaced) trkA-receptor (sv) Receptor, trkA (sv, replaced) trkA Receptor (en, replaced) trk1 Transforming Tryrosine Kinase (en, replaced) trk Proto-Oncogene Protein (en, replaced) Neurotrophic Tyrosine Kinase Receptor Type 1 (en, replaced) gp140(c-TRK) (en, replaced) gp140 c-trk (en, replaced) NTRK1 Receptor (en, replaced) p140-trkA (en, replaced) Receptor, Neurotrophic Tyrosine Kinase Type 1 (en, replaced) Proto-Oncogene Protein trk (en, replaced) Proto-Oncogene Products c-trk (en, replaced) c-trk Protein (en, replaced) |
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