ONKI3 | Medical Subject Headings

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Hierarchy:	Medical Subject Headings (MeSH) ∟ Disorders of Environmental Origin ∟ Poisoning ∟ Neurotoxicity Syndromes ∟ MPTP Poisoning 8 coordinate concepts ∟ Akathisia, Drug-Induced \| ∟ Alcohol-Induced Disorders, Nervous System \| ∟ Botulism \| ∟ Dyskinesia, Drug-Induced \| ∟ Heavy Metal Poisoning, Nervous System \| ∟ Neuroleptic Malignant Syndrome \| ∟ D010302Q000139* \| ∟ Parkinson Disease, Postencephalitic Medical Subject Headings (MeSH) ∟ Nervous System Diseases ∟ Central Nervous System Diseases ∟ Brain Diseases ∟ Basal Ganglia Diseases ∟ Parkinsonian Disorders ∟ Parkinson Disease, Secondary ∟ MPTP Poisoning 8 coordinate concepts ∟ Akathisia, Drug-Induced \| ∟ Alcohol-Induced Disorders, Nervous System \| ∟ Botulism \| ∟ Dyskinesia, Drug-Induced \| ∟ Heavy Metal Poisoning, Nervous System \| ∟ Neuroleptic Malignant Syndrome \| ∟ D010302Q000139* \| ∟ Parkinson Disease, Postencephalitic Medical Subject Headings (MeSH) ∟ Nervous System Diseases ∟ Central Nervous System Diseases ∟ Movement Disorders ∟ Parkinsonian Disorders ∟ Parkinson Disease, Secondary ∟ MPTP Poisoning 8 coordinate concepts ∟ Akathisia, Drug-Induced \| ∟ Alcohol-Induced Disorders, Nervous System \| ∟ Botulism \| ∟ Dyskinesia, Drug-Induced \| ∟ Heavy Metal Poisoning, Nervous System \| ∟ Neuroleptic Malignant Syndrome \| ∟ D010302Q000139* \| ∟ Parkinson Disease, Postencephalitic Medical Subject Headings (MeSH) ∟ Nervous System Diseases ∟ Neurotoxicity Syndromes ∟ MPTP Poisoning 8 coordinate concepts ∟ Akathisia, Drug-Induced \| ∟ Alcohol-Induced Disorders, Nervous System \| ∟ Botulism \| ∟ Dyskinesia, Drug-Induced \| ∟ Heavy Metal Poisoning, Nervous System \| ∟ Neuroleptic Malignant Syndrome \| ∟ D010302Q000139* \| ∟ Parkinson Disease, Postencephalitic X
Broader terms:	Medical Subject Headings (MeSH) ∟ Disorders of Environmental Origin ∟ Poisoning ∟ Neurotoxicity Syndromes ∟ MPTP Poisoning Medical Subject Headings (MeSH) ∟ Nervous System Diseases ∟ Central Nervous System Diseases ∟ Brain Diseases ∟ Basal Ganglia Diseases ∟ Parkinsonian Disorders ∟ Parkinson Disease, Secondary ∟ MPTP Poisoning Medical Subject Headings (MeSH) ∟ Nervous System Diseases ∟ Central Nervous System Diseases ∟ Movement Disorders ∟ Parkinsonian Disorders ∟ Parkinson Disease, Secondary ∟ MPTP Poisoning Medical Subject Headings (MeSH) ∟ Nervous System Diseases ∟ Neurotoxicity Syndromes ∟ MPTP Poisoning Neurotoxicity Syndromes > Poisoning > Disorders of Environmental Origin > Medical Subject Headings (MeSH) Parkinson Disease, Secondary > Parkinsonian Disorders > Basal Ganglia Diseases > Brain Diseases > Central Nervous System Diseases > Nervous System Diseases > Medical Subject Headings (MeSH) Parkinson Disease, Secondary > Parkinsonian Disorders > Movement Disorders > Central Nervous System Diseases > Nervous System Diseases > Medical Subject Headings (MeSH) Neurotoxicity Syndromes > Nervous System Diseases > Medical Subject Headings (MeSH) X
History note:	1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine/poisoning (1990-1999) \| Parkinson Disease, Secondary (1983-1999)X
historyNote*:	2000 X
publicMeSHNote*:	2000 X
Scope note:	A condition caused by the neurotoxin MPTP which causes selective destruction of nigrostriatal dopaminergic neurons. Clinical features include irreversible parkinsonian signs including rigidity and bradykinesia (PARKINSON DISEASE, SECONDARY). MPTP toxicity is also used as an animal model for the study of PARKINSON DISEASE. (Adams et al., Principles of Neurology, 6th ed, p1072; Neurology 1986 Feb;36(2):250-8) X
activeMeSHYear*:	2006 \| 2007X
dateCreated*:	1999-11-08X
dateEstablished*:	2000-01-01X
dateRevised*:	2005-06-30X
recordAuthorizer*:	sjnX
recordMaintainer*:	ssbX
recordOriginator*:	KEVX
Related term:	1-Methyl-4-phenylpyridinium X
Type:	Concept X
Coordinate terms:	Akathisia, Drug-Induced \| Alcohol-Induced Disorders, Nervous System \| Botulism \| Dyskinesia, Drug-Induced \| Heavy Metal Poisoning, Nervous System \| Neuroleptic Malignant Syndrome \| D010302Q000139* \| Parkinson Disease, Postencephalitic X
URI:	X
Labels and equivalent concepts:	MPTP-myrkytys (fi) MPTP-intoksikaatiot (fi, replaced) MPTP-myrkytykset (fi, replaced) Myrkytys, MPTP- (fi, replaced) MPTP-intoksikaatio (fi, replaced) MPTP-förgiftning (sv) Poisoning, 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine (en, replaced) MPTP-Induced Parkinsonism (en, replaced) Neurotoxicity Syndrome, MPTP (en, replaced) MPTP Neurotoxicity Syndrome (en, replaced) X
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