ONKI3 | Medical Subject Headings

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Hierarchy:	Medical Subject Headings (MeSH) ∟ Amino Acids, Peptides, and Proteins ∟ Peptides ∟ Intracellular Signaling Peptides and Proteins ∟ Apoptosis Regulatory Proteins ∟ Caspases ∟ Caspases, Initiator ∟ Caspase 1 5 coordinate concepts ∟ Caspase 10 \| ∟ Caspase 12 \| ∟ Caspase 2 \| ∟ Caspase 8 \| ∟ Caspase 9 Medical Subject Headings (MeSH) ∟ Amino Acids, Peptides, and Proteins ∟ Proteins ∟ Intracellular Signaling Peptides and Proteins ∟ Apoptosis Regulatory Proteins ∟ Caspases ∟ Caspases, Initiator ∟ Caspase 1 5 coordinate concepts ∟ Caspase 10 \| ∟ Caspase 12 \| ∟ Caspase 2 \| ∟ Caspase 8 \| ∟ Caspase 9 Medical Subject Headings (MeSH) ∟ Enzymes and Coenzymes ∟ Enzymes ∟ Hydrolases ∟ Peptide Hydrolases ∟ Endopeptidases ∟ Cysteine Endopeptidases ∟ Caspases ∟ Caspases, Initiator ∟ Caspase 1 5 coordinate concepts ∟ Caspase 10 \| ∟ Caspase 12 \| ∟ Caspase 2 \| ∟ Caspase 8 \| ∟ Caspase 9 X
Broader terms:	Medical Subject Headings (MeSH) ∟ Amino Acids, Peptides, and Proteins ∟ Peptides ∟ Intracellular Signaling Peptides and Proteins ∟ Apoptosis Regulatory Proteins ∟ Caspases ∟ Caspases, Initiator ∟ Caspase 1 Medical Subject Headings (MeSH) ∟ Amino Acids, Peptides, and Proteins ∟ Proteins ∟ Intracellular Signaling Peptides and Proteins ∟ Apoptosis Regulatory Proteins ∟ Caspases ∟ Caspases, Initiator ∟ Caspase 1 Medical Subject Headings (MeSH) ∟ Enzymes and Coenzymes ∟ Enzymes ∟ Hydrolases ∟ Peptide Hydrolases ∟ Endopeptidases ∟ Cysteine Endopeptidases ∟ Caspases ∟ Caspases, Initiator ∟ Caspase 1 Caspases, Initiator > Caspases > Apoptosis Regulatory Proteins > Intracellular Signaling Peptides and Proteins > Peptides > Amino Acids, Peptides, and Proteins > Medical Subject Headings (MeSH) Caspases, Initiator > Caspases > Apoptosis Regulatory Proteins > Intracellular Signaling Peptides and Proteins > Proteins > Amino Acids, Peptides, and Proteins > Medical Subject Headings (MeSH) Caspases, Initiator > Caspases > Cysteine Endopeptidases > Endopeptidases > Peptide Hydrolases > Hydrolases > Enzymes > Enzymes and Coenzymes > Medical Subject Headings (MeSH) X
History note:	Cysteine Proteinases (1995-1998) \| Metalloproteinases (1989-1994)X
historyNote*:	99; use CASPASE 1 (NM) 1989-98 X
publicMeSHNote*:	99; INTERLEUKIN 1BETA CONVERTING ENZYME (now CASPASE 1) was indexed under CYSTEINE PROTEINASES 1995-98 & METALLOPROTEINASES 1989-94 X
Scope note:	A long pro-domain caspase that has specificity for the precursor form of INTERLEUKIN-1BETA. It plays a role in INFLAMMATION by catalytically converting the inactive forms of CYTOKINES such as interleukin-1beta to their active, secreted form. Caspase 1 is referred as interleukin-1beta converting enzyme and is frequently abbreviated ICE. X
activeMeSHYear*:	2007X
dateCreated*:	1998-06-10X
dateEstablished*:	1999-01-01X
dateRevised*:	2006-07-05X
recordAuthorizer*:	sjnX
recordMaintainer*:	jmpX
recordOriginator*:	ADPX
Related term:	Apoptosis \| Interleukin-1 X
Type:	Concept X
Coordinate terms:	Caspase 10 \| Caspase 12 \| Caspase 2 \| Caspase 8 \| Caspase 9 X
URI:	X
Labels and equivalent concepts:	Kaspaasi 1 (fi) IL-1-beetaa konvertoiva entsyymi (fi, replaced) ICE-proteaasi (fi, replaced) IL-1beetaa konvertoiva entsyymi (fi, replaced) Interleukiini-1-beetaa konvertoiva entsyymi (fi, replaced) Interleukiini-1beetaa konvertoiva entsyymi (fi, replaced) Kaspas-1 (sv) Pro-Caspase-1 (en, replaced) Interleukin-1beta Converting Enzyme (en, replaced) IL-1 beta Convertase (en, replaced) ICE Protease (en, replaced) IL-1 beta-Converting Enzyme (en, replaced) IL1BC Enzyme (en, replaced) Interleukin-1 Converting Enzyme (en, replaced) CASP1 Caspase (en, replaced) X
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