ONKI3 | Medical Subject Headings

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Hierarchy:	Medical Subject Headings (MeSH) ∟ Carbohydrates ∟ Glycosides ∟ Macrolides ∟ Sirolimus 21 coordinate concepts ∟ Amphotericin B \| ∟ Antimycin A \| ∟ Brefeldin A \| ∟ Candicidin \| ∟ Cytochalasins \| ∟ Epothilones \| ∟ Erythromycin \| ∟ Filipin \| ∟ Ivermectin \| ∟ Josamycin \| ∟ Leucomycins \| ∟ Lucensomycin \| ∟ Maytansine \| ∟ Mepartricin \| ∟ Miocamycin \| ∟ Natamycin \| ∟ Nystatin \| ∟ Oleandomycin \| ∟ Oligomycins \| ∟ Tacrolimus \| ∟ Tylosin Medical Subject Headings (MeSH) ∟ Organic Chemicals ∟ Lactones ∟ Macrolides ∟ Sirolimus 21 coordinate concepts ∟ Amphotericin B \| ∟ Antimycin A \| ∟ Brefeldin A \| ∟ Candicidin \| ∟ Cytochalasins \| ∟ Epothilones \| ∟ Erythromycin \| ∟ Filipin \| ∟ Ivermectin \| ∟ Josamycin \| ∟ Leucomycins \| ∟ Lucensomycin \| ∟ Maytansine \| ∟ Mepartricin \| ∟ Miocamycin \| ∟ Natamycin \| ∟ Nystatin \| ∟ Oleandomycin \| ∟ Oligomycins \| ∟ Tacrolimus \| ∟ Tylosin Medical Subject Headings (MeSH) ∟ Polycyclic Compounds ∟ Macrocyclic Compounds ∟ Macrolides ∟ Sirolimus 21 coordinate concepts ∟ Amphotericin B \| ∟ Antimycin A \| ∟ Brefeldin A \| ∟ Candicidin \| ∟ Cytochalasins \| ∟ Epothilones \| ∟ Erythromycin \| ∟ Filipin \| ∟ Ivermectin \| ∟ Josamycin \| ∟ Leucomycins \| ∟ Lucensomycin \| ∟ Maytansine \| ∟ Mepartricin \| ∟ Miocamycin \| ∟ Natamycin \| ∟ Nystatin \| ∟ Oleandomycin \| ∟ Oligomycins \| ∟ Tacrolimus \| ∟ Tylosin X
Broader terms:	Medical Subject Headings (MeSH) ∟ Carbohydrates ∟ Glycosides ∟ Macrolides ∟ Sirolimus Medical Subject Headings (MeSH) ∟ Organic Chemicals ∟ Lactones ∟ Macrolides ∟ Sirolimus Medical Subject Headings (MeSH) ∟ Polycyclic Compounds ∟ Macrocyclic Compounds ∟ Macrolides ∟ Sirolimus Macrolides > Glycosides > Carbohydrates > Medical Subject Headings (MeSH) Macrolides > Lactones > Organic Chemicals > Medical Subject Headings (MeSH) Macrolides > Macrocyclic Compounds > Polycyclic Compounds > Medical Subject Headings (MeSH) X
History note:	Polyenes (1976-1998)X
historyNote*:	99; use SIROLIMUS (NM) 1980-97 X
publicMeSHNote*:	99; RAPAMYCIN (now SIROLIMUS) was indexed under POLYENES 1976-98 X
Scope note:	A macrolide compound obtained from Streptomyces hygroscopicus that acts by selectively blocking the transcriptional activation of cytokines thereby inhibiting cytokine production. It is bioactive only when bound to IMMUNOPHILINS. Sirolimus is a potent immunosuppressant and possesses both antifungal and antineoplastic properties. X
activeMeSHYear*:	2006 \| 2007X
dateCreated*:	1998-06-11X
dateEstablished*:	1999-01-01X
dateRevised*:	2005-06-30X
recordAuthorizer*:	sjnX
recordMaintainer*:	CCRX
recordOriginator*:	ADPX
Type:	Concept X
Coordinate terms:	Amphotericin B \| Antimycin A \| Brefeldin A \| Candicidin \| Cytochalasins \| Epothilones \| Erythromycin \| Filipin \| Ivermectin \| Josamycin \| Leucomycins \| Lucensomycin \| Maytansine \| Mepartricin \| Miocamycin \| Natamycin \| Nystatin \| Oleandomycin \| Oligomycins \| Tacrolimus \| Tylosin X
URI:	X
Labels and equivalent concepts:	Sirolimuusi (fi) Rapamysiini (fi, replaced) Rapamycin (sv, replaced) Rapamun (sv, replaced) Wyeth Brand of Sirolimus (en, replaced) Rapamycin (en, replaced) X
Share:	X